Anesthesiology Clinics, Год журнала: 2023, Номер 41(2), С. 383 - 394
Опубликована: Апрель 8, 2023
Язык: Английский
British Journal of Anaesthesia, Год журнала: 2022, Номер 130(1), С. e137 - e147
Опубликована: Сен. 13, 2022
Язык: Английский
Процитировано
49
European Journal of Pain, Год журнала: 2025, Номер 29(4)
Опубликована: Фев. 21, 2025
ABSTRACT Purpose This study aimed to investigate the association between chronic postsurgical pain (CPSP) and risk of dementia, addressing a significant gap in existing literature highlighting potential implications for clinical practice public health. Patients Methods Utilising data from Taiwan's National Health Insurance Research Database, propensity score‐matched cohort was conducted involving 142,682 patients who underwent major surgery 2004 2018. CPSP defined as prolonged analgesic use post‐surgery, dementia diagnosis tracked until December 31, 2022. Multivariable Cox regression models were employed calculate adjusted hazard ratios (aHRs) versus non‐CPSP groups. Results Before score matching, ( n = 37,438) exhibited higher with aHRs 1.35 (95% CI: 1.30–1.40). After aHR remained elevated at 1.31 1.26–1.37), indicating risk. Subgroup analysis confirmed this across various demographic factors, sensitivity reinforcing robustness findings. Conclusion establishes an independent predictor risk, importance postoperative management mitigating long‐term cognitive outcomes. Approximately 30% post‐CPSP presents opportunity reduction through effective strategies, emphasising need targeted interventions address critical healthcare issue. Significance provides compelling evidence that significantly increases previously underexplored connection decline. By establishing our findings underscore strategies surgical patients, particularly mitigate heightened improve
Язык: Английский
Процитировано
1
Pain and Therapy, Год журнала: 2022, Номер 12(1), С. 117 - 139
Опубликована: Окт. 13, 2022
Determining the prevalence of chronic postsurgical pain (CPSP) after video-assisted thoracoscopic surgery (VATS) and identifying CPSP predictors should improve prognosis patients undergoing VATS. Although several studies have investigated VATS, there were significant dissimilarities in findings due to confounding predictors.PubMed, Cochrane, MEDLINE, Web Science, Chinese Biomedical Literature, China National Knowledge Infrastructure databases comprehensively searched using Medical Subject Headings terms "pain, postoperative," "thoracic surgery, video-assisted," all related free from inception until March 27, 2022. The Stata metaprop package was used analyze incidence following Furthermore, pooled odds ratios (OR) or standardized mean differences (SMD) their corresponding 95% confidence intervals (95% CI) calculated, qualitative analyses performed for that could not be assessed quantitatively evaluate effects included risk factors on occurrence CPSP. Unadjusted utilized consider impact non-significant estimates if original study did report them.Of 4302 studies, 183 considered eligible, 17 finally this study. overall VATS 35.3% CI 27.1-43.5%). synthesis results revealed female sex, age, acute postoperative definite number ports, operation time, duration drainage, insufficient analgesia also predictors. Consistent, quantitative showed aforementioned closely Only by analysis, chemotherapy an educational level less than junior school Other displayed no evidence unclear association with VATS.This preliminarily determined based existing literature. Female identified as other potential analyzed. However, a result inclusion retrospective inevitable limitations systematic review meta-analysis, still need verified large-scale prospective clinical studies.CRD42022323179.
Язык: Английский
Процитировано
24
BMC Geriatrics, Год журнала: 2023, Номер 23(1)
Опубликована: Май 12, 2023
Abstract Background Due to the continued growth of surgical procedures in older adults and significant impact chronic postsurgical pain (CPSP), it is crucial improve our understanding occurrence CPSP as well appropriate prevention treatment. We therefore conducted this study determine incidence, characteristics risk factors elderly patients at both 3 6 months after surgery. Methods Elderly (aged ≥ 60 years) undergoing elective surgery institution between April 2018 March 2020 were prospectively enrolled study. Data on demographics, preoperative psychological well-being, intraoperative anesthesia management, acute postoperative intensity collected. At surgery, received telephone interview completed questionnaires regarding characteristics, analgesic consumption, interference with activities daily living (ADL). Results A total 1065 followed up for included final analysis. operation, incidence was 35.6% [95% confidence interval (95% CI) 32.7 − 38.8%] 21.5% CI 19.0% 23.9%), respectively. cause negative impacts patient’s ADL most particularly mood. Neuropathic features found 45.1% months. months, 31.0% those reported that had neuropathic features. Preoperative anxiety [3 months: Odds ratio (OR) 2.244, 95% 1.693 2.973; OR 2.397, 1.745 3.294], depression (3 1.709, 1.292 2.261; 1.565, 1.136–2.156), orthopedic 1.927, 1.112 3.341; 2.484, 1.220 5.061), higher severity movement within 24 h 1.317, 1.191 1.457; 1.177 1.475) associated a independently Conclusions common complication patients. depression, greater are an increased CPSP. It should be kept mind developing interventions reduce optimizing management will effective reducing development population.
Язык: Английский
Процитировано
15
Asia-Pacific Journal of Oncology Nursing, Год журнала: 2025, Номер unknown, С. 100693 - 100693
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Frontiers in Medicine, Год журнала: 2025, Номер 12
Опубликована: Март 31, 2025
Background The analgesic efficacy of liposomal bupivacaine (LB) for ultrasound-guided erector spinae plane block (ESPB) and thoracoscopic intercostal nerve (ICNB) in thoracic surgery remains uncertain. This study aims to evaluate the anesthesiologist-performed ESPB using LB versus surgeon-administrated ICNB with patients undergoing video-assisted (VATS) lung resection. Methods single-center, prospective, randomized, double-blinded trial will include 120 adult scheduled VATS Patients be randomly assigned 1:1 group or group. Each patient receive either an at end surgery, along patients-controlled intravenous analgesia (PCIA) as part a postoperative multimodal analgesia. primary outcome is average numeric rating scale (NRS) pain scores rest over 72 h postoperatively (average three 24-h time points: 24, 48, h). Secondary outcomes NRS during activity postoperatively, Quality Recovery 15 first press on PCIA device, total opioid consumption within initiate independent bedside mobilization, length hospital stay, incidence chronic (defined score ≥ 1) 3 months post-surgery. Analyses performed modified intention-to-treat population. Discussion We hypothesize that result lower compared findings this aim provide evidence optimize regimens Clinical registration http://www.chictr.org.cn , identifier ChiCTR2400092927.
Язык: Английский
Процитировано
0
BMC Pulmonary Medicine, Год журнала: 2025, Номер 25(1)
Опубликована: Апрель 7, 2025
Lung cancer surgery has evolved significantly, with minimally invasive video-assisted thoracic (VATS) procedures being compared traditional open thoracotomies. The incidence of postoperative wound infections is a significant factor influencing the choice surgical technique. This systematic review and meta-analysis aim to evaluate impact thoracoscopic versus thoracotomy on in lung patients. Following PRISMA guidelines, comprehensive search across PubMed, Embase, Web Science, Cochrane Library was conducted September 19, 2023, without time or language restrictions. Peer-reviewed randomized controlled trials, cohort studies, case-control studies reporting were included. Studies not differentiating between techniques focusing irrelevant populations excluded. Data extraction quality assessment independently carried out by two reviewers, using fixed-effect model for due absence heterogeneity (I2 = 0.0%, P 0.766). A total six articles indicated low risk bias most domains. pooled results showed that had twofold increased (OR 2.00, 95% CI: 1.04-3.85) VATS procedures. Publication funnel plots Egger's test revealed no biases (P > 0.05). findings suggest associated lower thoracotomy, which implications decision-making treatment. Not applicable.
Язык: Английский
Процитировано
0
Expert Review of Neurotherapeutics, Год журнала: 2023, Номер 23(12), С. 1297 - 1310
Опубликована: Ноя. 24, 2023
Introduction Chronic postsurgical pain (CPSP) is a prevalent condition that can diminish health-related quality of life, cause functional deficits, and lead to patient distress. Rates CPSP are higher for certain types surgeries than others (thoracic, breast, or lower extremity amputations) but occur after even uncomplicated minimally invasive procedures. has multiple mechanisms, always starts as acute pain, which involves inflammatory processes may encompass direct indirect neural injury. Risk factors largely known many, such female sex, younger age, type surgery, not modifiable. The best strategy against quickly effectively treat postoperative using multimodal analgesic regimen safe, effective, spares opioids.
Язык: Английский
Процитировано
9
Surgery, Год журнала: 2024, Номер 176(4), С. 1263 - 1272
Опубликована: Июль 12, 2024
Язык: Английский
Процитировано
2
Regional Anesthesia & Pain Medicine, Год журнала: 2023, Номер 49(8), С. 581 - 601
Опубликована: Янв. 27, 2023
Chronic pain begins with acute pain. Physicians tend to classify by duration (acute vs chronic) and mechanism (nociceptive, neuropathic nociplastic). Although this taxonomy may facilitate diagnosis documentation, such categories are some degree arbitrary constructs, significant overlap in terms of mechanisms treatments. In clinical practice, there myriad different definitions for chronic a substantial portion involves mixed phenotypes. Classification based on acuity informs management at all levels constitutes critical part guidelines treatment care. Yet specialty care is often siloed, advances understanding lagging years behind areas which these developments should be the forefront practice. For example, perioperative management, enhanced recovery protocols not standardized drive without consideration mechanisms, many cases incongruent personalized medicine mechanism-based treatment. educational document, we discuss classification as it pertains commonly performed surgical procedures. Our goal provide reference physician decision-making (both therapy) period.
Язык: Английский
Процитировано
6