Association between the red blood cell distribution width-albumin ratio and cardiovascular diseases DOI Creative Commons
Yan Liu, Shougang Sun, Ling Liu

и другие.

Frontiers in Cardiovascular Medicine, Год журнала: 2025, Номер 12

Опубликована: Апрель 9, 2025

Cardiovascular disease (CVD) is the major cause of death globally, ranking first in terms morbidity and mortality among non-communicable diseases. Red blood cell distribution width (RDW) albumin (ALB) possess potential clinical application values. Moreover, ratio two, namely RAR, might hold more advantages diagnosis. However, relationship between RAR CVD general population has not been studied yet. This represents a study encompassing 12,765 subjects. Logistic regression, Cox restricted cubic splines, mediation analysis, receiver operating characteristic curves were utilized to probe into association CVD, cardiovascular rate all-cause rate. A total participants enrolled this study, The mean age was 47.47 ± 16.33 years. regression revealed that positively correlated with CVD. Furthermore, COX also illustrated non-linearly associated both (all-cause mortality: p-non-linear = 0.0322; 0.0280). Additionally, ROC results indicated at various time points, exhibited stronger discriminatory capacity for compared HbA1c partially mediated Subgroup analysis interaction findings demonstrated hypertension race exerted significant influence on significantly linked an elevated risk higher level, greater Thus, could potentially be independent factor underscores crucial value discrimination management

Язык: Английский

Association between the red blood cell distribution width-albumin ratio and cardiovascular diseases DOI Creative Commons
Yan Liu, Shougang Sun, Ling Liu

и другие.

Frontiers in Cardiovascular Medicine, Год журнала: 2025, Номер 12

Опубликована: Апрель 9, 2025

Cardiovascular disease (CVD) is the major cause of death globally, ranking first in terms morbidity and mortality among non-communicable diseases. Red blood cell distribution width (RDW) albumin (ALB) possess potential clinical application values. Moreover, ratio two, namely RAR, might hold more advantages diagnosis. However, relationship between RAR CVD general population has not been studied yet. This represents a study encompassing 12,765 subjects. Logistic regression, Cox restricted cubic splines, mediation analysis, receiver operating characteristic curves were utilized to probe into association CVD, cardiovascular rate all-cause rate. A total participants enrolled this study, The mean age was 47.47 ± 16.33 years. regression revealed that positively correlated with CVD. Furthermore, COX also illustrated non-linearly associated both (all-cause mortality: p-non-linear = 0.0322; 0.0280). Additionally, ROC results indicated at various time points, exhibited stronger discriminatory capacity for compared HbA1c partially mediated Subgroup analysis interaction findings demonstrated hypertension race exerted significant influence on significantly linked an elevated risk higher level, greater Thus, could potentially be independent factor underscores crucial value discrimination management

Язык: Английский

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