Therapeutic Strategies and Genetic Implications for Periodontal Disease Management: A Systematic Review

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(13), С. 7217 - 7217

Опубликована: Июнь 29, 2024

The objective of this review is to identify the microbiological alterations caused by various therapy modalities critically analyzing current findings. We limited our search English-language papers published between 1 January 2004 and 7 May 2024 in PubMed, Scopus, Web Science that were relevant topic. In approach, Boolean keywords "microbio*" AND "periodontitis" used. A total 5152 obtained from databases (2205), PubMed (1793), Scopus (1154). This resulted 3266 articles after eliminating duplicates (1886), 1411 entries eliminated their titles abstracts examined. qualitative analysis 22 final included study. Research on periodontal disease shows periodontitis alters oral microbiome increases antibiotic resistance. Treatments like scaling root planing (SRP), especially when combined with minocycline, improve clinical outcomes reducing harmful bacteria. Comprehensive mechanical debridement antibiotics, probiotics, EMD bone grafts, other adjunctive therapies enhances health. Personalized treatment strategies advanced microbial analyses are crucial for effective management resistance control.

Язык: Английский

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The Role of Curcumin in Oral Health and Diseases: A Systematic Review

Antioxidants, Год журнала: 2024, Номер 13(6), С. 660 - 660

Опубликована: Май 28, 2024

Curcumin (Curcumin) belongs to the polyphenol family. It is extracted by drying root of a plant Asian origin, belonging Zingiberaceae The best-known species Curcumincuma Longa. has been recognized as having great therapeutic powers since ancient times. Studies on curcumin have confirmed its powerful antioxidant properties, preventing both formation free radicals and their neutralization, anti-inflammatory, antibacterial, immunological, neuroprotective well being regulator intestinal microbiota with beneficial effects clinical manifestations metabolic syndrome. Our study aimed highlight how all these aspects could benefit oral health, improving course pathological processes. effect mouthwashes, curcumin-based gels regulation bacterial plaque in control gingivitis, was largely comparable that using 0.20% chlorhexidine, fewer side effects. Being highly hydrophobic substance, it high permeability cross cell membrane. Bioavailability increases when combined liposoluble substances (e.g., olive oil) piperine, which improves absorption. also negligible degree toxicity, making an excellent alternative use gold standard products for disinfection.

Язык: Английский

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Bidirectional Association between Periodontitis and Thyroid Disease: A Scoping Review

International Journal of Environmental Research and Public Health, Год журнала: 2024, Номер 21(7), С. 860 - 860

Опубликована: Июнь 30, 2024

Periodontitis is a chronic inflammatory disease of the tissues surrounding and supporting teeth. Due to development inflammation, periodontitis can contribute several systemic diseases, including thyroid disease. Thyroid pathology includes benign, malignant, autoimmune conditions leading hypothyroidism, hyperthyroidism, or euthyroidism. Alterations in hormones, especially reveal significant oral manifestations, periodontitis. This scoping review aims explore probable causal relationship between disease, terms epidemiology, pathogenesis, treatment. The search strategy follows PRISMA-ScR guidelines. PubMed, Scopus, Web Science, Cochrane were searched from January 2014 2024, entering MESH “periodontitis” “thyroid”. Of 153 initial records, 20 articles selected discussed. There high prevalence among patients with cancer. causes at basis this association are genetic factors, microbiome, proinflammatory cytokines. Periodontal treatment, specifically scaling root planning, ameliorate parameters. Although there few randomized controlled studies literature, lays foundation for bidirectional link which is, once again, inflammation.

Язык: Английский

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Diagnosis and Orthodontic Treatment of Obstructive Sleep Apnea Syndrome Children—A Systematic Review

Diagnostics, Год журнала: 2024, Номер 14(3), С. 289 - 289

Опубликована: Янв. 29, 2024

Obstructive sleep apnea syndrome (OSAS) is a respiratory illness that associated with recurrent episodes of either partial or full obstruction the upper airways, apnea, among other disorders. This study aims to analyze, through literature review, whether orthodontic treatment can be good strategy for this type disorder. We performed database search on Scopus, Web Science, and Pubmed keywords OSA(S) orthodontics select papers under evaluation. The criteria inclusion were articles related children undergoing an clinical studies case series, excluding systematic reviews, narrative meta-analyses, adult studies, animal models, in vitro studies. screening phase ended selection 16 publications work. RME, rapid maxillary expansion, turned out preferred cases pediatric OSAS. goal procedure increase hard palate’s transverse diameter by reopening mid-palatal suture. Children contraction dental malocclusion typically undergo such have excellent results. However, OSAS multifactorial disorder; it does not seem morphology oral cavity, therefore, always possible cope problem exclusively treatment.

Язык: Английский

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Silver Diamine Fluoride in Pediatric Dentistry: Effectiveness in Preventing and Arresting Dental Caries—A Systematic Review

Children, Год журнала: 2024, Номер 11(4), С. 499 - 499

Опубликована: Апрель 22, 2024

Background: Tooth decay is considered a global scourge by the World Health Organization (WHO) starting at an early age. In recent years, silver diamine fluoride (SDF) has regained interest, particularly in pediatric dentistry, used to prevent development of carious lesions or arrest their progression. Objective: The aim this study was assess, through systematic review literature, effectiveness SDF, pedodontics, temporary teeth, preventing arresting dental caries. Material and Methods: An electronic search conducted on PubMed, Web Science Scopus. effect SDF both permanent teeth been considered. Results: inclusion criteria identified 16 randomized controlled trials involving patients aged 18 months 13 years followed over period 12–30 months. Conclusions: practical, accessible effective non-invasive way caries teeth. Its application requires regular monitoring. resulting black spot diminished immediate potassium iodide but may affect its effectiveness.

Язык: Английский

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Importance of periodontal phenotype in periodontics and restorative dentistry: a systematic review

BMC Oral Health, Год журнала: 2024, Номер 24(1)

Опубликована: Янв. 8, 2024

Abstract Background Periodontal phenotype is regarded to be one of the key factors influencing efficacy restorative therapies in dental practice. The objective systematic review was explore importance thin and thick periodontal phenotypes how they affect outcome by looking at a number academic publications from various online databases. Methods Following PRISMA guidelines (Preferred Reporting Items for Systematic Review standards), relevant data will searched retrieved three significant scientific databases, including PubMed, EBSCO, Scopus. articles with full texts that matched keywords published English between 2018 2023 were taken into consideration. Results majorities these based on type their impact treatment outcomes selected. initial search yielded total 530 articles. Only 273 review’s objectives, considered determining eligibility. 20 eligible analysis. Conclusion Understanding anatomical aspects crucial both periodontology dentistry. clinical restorative, prosthetic, orthodontic, surgical, determined large part phenotype, which also plays role failure or success treatments. Trial registration This study protocol registered International Prospective Register Reviews (PROSPERO) dated 16th June ID CRD42023432568.

Язык: Английский

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Prevalence of temporomandibular disorders diagnosis in patients treated with Herbst appliance: a systematic review and meta-analysis

BMC Oral Health, Год журнала: 2024, Номер 24(1)

Опубликована: Янв. 28, 2024

Abstract Background The Herbst appliance is an excellent therapy for treating class II malocclusions with increased overjet. Its mechanics involve propelling the mandibular bone using two pistons patient cannot remove. so-called bite-jumping keeps mandible in a more anterior position variable period, usually at least 6 months. This does not inhibit joint functions and movements, although there are scientific papers literature investigating whether this can lead to temporomandibular disorders. systematic review aims evaluate Herbst’s device cause diseases by assessing presence of TMD patients before after treatment. Methods A search up 3 May 2023 was carried out on three online databases: PubMed, Scopus Web Science. Only studies that evaluated Helkimo scores Manual functional analysis were considered, as assessed difference therapy. Review Manager version 5.2.8 (Cochrane Collaboration) used pooled analysis. We measured odds ratio (OR) between groups (pre post-Herbst). Results included 60. Fifty-seven excluded. In addition, manual performed. After phase, four articles considered study, one which found through search. overall effect showed no prevalence pre-Herbst post-Herbst (OR 0.74; 95% CI: 0.33–1.68). Conclusion seems increase incidence treated patients; contrary, it appears decrease it. Further needed assess possible influence TMDs.

Язык: Английский

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Stem Cells: Present Understanding and Prospects for Regenerative Dentistry

Journal of Functional Biomaterials, Год журнала: 2024, Номер 15(10), С. 308 - 308

Опубликована: Окт. 15, 2024

Regenerative medicine in dentistry focuses on repairing damaged oral tissues using advanced tools like stem cells, biomaterials, and tissue engineering (TE). Mesenchymal cells (MSCs) from dental sources, such as pulp periodontal ligament, show significant potential for regeneration due to their proliferative differentiative abilities. This systematic review, following PRISMA guidelines, evaluated fifteen studies identified effective strategies improving dental, periodontal, bone through scaffolds, secretomes, bioengineering methods. Key advancements include the use of (DPSCs) ligament (PDLSCs) boost cell viability manage inflammation. Additionally, pharmacological agents matrine surface modifications biomaterials improve adhesion promote osteogenic differentiation. By integrating these approaches, regenerative TE can optimize therapies enhance patient outcomes. review highlights challenges this field, providing a critical assessment current research future directions.

Язык: Английский

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Evaluating the success rates and effectiveness of surgical and orthodontic interventions for impacted canines: a systematic review of surgical and orthodontic interventions and a case series

BMC Oral Health, Год журнала: 2025, Номер 25(1)

Опубликована: Фев. 24, 2025

Язык: Английский

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Modern Approaches to Children’s Oral Health: Contemporary Risk Factors and the Influence of Parental Education

IntechOpen eBooks, Год журнала: 2025, Номер unknown

Опубликована: Март 11, 2025

Children’s oral health is shaped by various contemporary risk factors that extend beyond genetics, with lifestyle habits, diet, and environmental influences playing a significant role. One of the most pressing concerns today high consumption sugary foods drinks, which significantly contributes to prevalence dental caries among young children. Additionally, digital media sedentary behaviors can indirectly affect encouraging unhealthy dietary patterns. Parental education key determinant in outcomes Well-informed parents are more likely implement preventive measures, such as regular check-ups, proper hygiene routines, healthy diet. Conversely, lower levels may lack awareness or resources foster good habits their children, leading higher rates issues. A modern approach children’s emphasizes care, early intervention, educating both children on importance hygiene. This also encourages collaboration between professionals, pediatricians, educators create supportive environment for long-term health. By addressing empowering knowledge, path toward improved becomes attainable.

Язык: Английский

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