Root Resorption during Orthodontic Treatment with Clear Aligners vs. Fixed Appliances—A Systematic Review

Applied Sciences, Год журнала: 2024, Номер 14(2), С. 690 - 690

Опубликована: Янв. 13, 2024

The external apical root resorption that occurs during orthodontic treatment was the focus of this study, using either fixed appliances (FA) or clear aligners (CA). Using Boolean keywords “APICAL ROOT RESORPTION” and “CLEAR ALIGNERS”, study searched PubMed, Scopus, Web Science, with a restriction to English-language publications. A total 50 publications were found by computerized search, but after eliminating duplicates, completing reviews, determining eligibility, only 9 papers could be used in study. In conclusion, (ARR) is frequent consequence tooth movement mainly affects lower incisors, which may compromise success procedure health patient’s teeth. Several variables, including type tooth, have an impact on severity ARR.

Язык: Английский

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Celiac Disease-Related Enamel Defects: A Systematic Review

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(5), С. 1382 - 1382

Опубликована: Фев. 28, 2024

Introduction: This systematic review aims to elucidate the intricate correlation between celiac disease (CD) and dental enamel defects (DED), exploring pathophysiological mechanisms, oral health implications, a dentist’s role in early diagnosis. Materials methods: Following PRISMA guidelines, comprehensive search from 1 January 2013 2024 across PubMed, Cochrane Library, Scopus, Web of Science identified 153 publications. After exclusions, 18 studies met inclusion criteria for qualitative analysis. Inclusion involved study types (RCTs, RCCTs, case series), human participants, English language, full-text available. Results: The yielded publications, with meeting Notable findings include high prevalence DED CD patients, ranging 50 94.1%. Symmetrical chronological defects, according Aine’s classification, were predominant, significant associations observed severity defect extent. Conclusions: recognition lesions, particularly through may signal potential even absence gastrointestinal symptoms. Correlations conditions like molar incisor hypomineralization (MIH) emphasize crucial Collaboration dentists gastroenterologists is essential effective monitoring management. consolidates current knowledge, laying groundwork future research promoting interdisciplinary collaboration improved CD-related outcomes. Further large-scale prospective recommended deepen our understanding these issues.

Язык: Английский

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Clear Aligners in the Growing Patient: A Systematic Review

Children, Год журнала: 2024, Номер 11(4), С. 385 - 385

Опубликована: Март 23, 2024

Mixed dentition represents a critical phase in the oral development of pediatric patients, characterized by simultaneous presence primary and permanent teeth. This article proposes comprehensive systematic review application aligners as an innovative methodology managing mixed dentition. The objective is to explore efficacy, safety, acceptability this emerging orthodontic technology evolving age group. focuses on randomized controlled trials, cohorts, observational studies investigating use patients with Clinical, radiographic, psychosocial parameters will be considered assess overall impact aligner therapy dental development. An in-depth analysis such data aims provide overview potential orthodontics. Expected outcomes may contribute outlining practical guidelines targeted therapeutic strategies for orthodontists involved Furthermore, identify gaps current research suggest future directions exploring transparent dentition, thereby contributing ongoing evolution evidence-based practices.

Язык: Английский

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Prediction of interactomic hub genes in PBMC cells in type 2 diabetes mellitus, dyslipidemia, and periodontitis

BMC Oral Health, Год журнала: 2024, Номер 24(1)

Опубликована: Март 26, 2024

Abstract Background and objective In recent years, the complex interplay between systemic health oral well-being has emerged as a focal point for researchers healthcare practitioners. Among several important connections, convergence of Type 2 Diabetes Mellitus (T2DM), dyslipidemia, chronic periodontitis, peripheral blood mononuclear cells (PBMCs) is remarkable example. These components collectively contribute to network interactions that extends beyond their domains, underscoring intricate nature human health. current study, bioinformatics analysis was utilized predict interactomic hub genes involved in type diabetes mellitus periodontitis relationships (PBMC) by machine learning algorithms. Materials Methods Gene Expression Omnibus datasets were identify linked mellitus(T2DM), Periodontitis (GSE156993).Gene Ontology (G.O.) Enrichr, Genemania, Kyoto Encyclopedia Genes Genomes (KEGG) pathways used identification functionalities genes. The expression D.E.G.s confirmed, an orange tool Result decision tree, AdaBoost, Random Forest had A.U.C. 0.982, 1.000, 0.991 R.O.C. curve. AdaBoost model showed accuracy (1.000). findings imply good predictive value may support clinical evaluation assist accurately detecting associated with T2DM dyslipidemia. Moreover, p-value < 0.05 A.U.C.>0.90, which excellent value, thus considered Conclusion identified present study immensely fundamentals molecular mechanisms occurring PBMC progression presence They be potential biomarkers offer novel therapeutic strategies inflammatory diseases.

Язык: Английский

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The Role of Sulfhydryl (Thiols) Groups in Oral and Periodontal Diseases

Biomedicines, Год журнала: 2024, Номер 12(4), С. 882 - 882

Опубликована: Апрель 16, 2024

Aim. The sulfhydryl (thiols) group of glutathione plays an important role in the neutralization foreign organic compounds and reduction peroxides. purpose study is to evaluate concentration groups gingival tissue healthy individuals those with gingivitis or periodontitis, examine differences between these groups. Material methods. To assess we used spectrophotometric analysis using dithionitrobenzoate (DTNB) as a reagent measure accessible present proteins. sample was divided into three distinct groups: periodontal health, gingivitis, different indices were status participants. Next, statistical conducted compare concentrations among patients. Conclusions. results this showed significantly decreased levels from patients compared people (control group). These confirm defense against free radicals. They share significant detoxification, signal transduction, apoptosis, various other functions at molecular level.

Язык: Английский

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Attenuation of orthodontically induced inflammatory root resorption by using low-intensity pulsed ultrasound as a therapeutic modality- a systematic review

BMC Oral Health, Год журнала: 2024, Номер 24(1)

Опубликована: Янв. 10, 2024

Abstract Ultrasound is an effective tool for both diagnostic and therapeutic applications. As imaging tool, ultrasound has mostly been used real-time noninvasive imaging. propagates through a material, reflected radio-frequency (RF) signal generated when encountering mismatch in acoustic impedance. While traditionally recognized its capabilities, the application of broadened to encompass interventions, most notably form Low-Intensity Pulsed (LIPUS). (LIPUS) mechanical energy transmitted transcutaneously by high-frequency pressure waves. The intensity LIPUS (30 mW/cm2) within range intensities purposes (1–50 regarded as non-thermal, non-destructive, permeating living tissues triggering cascade biochemical responses at cellular level. device produces 200 µs burst 1.5 MHz sine waves, that repeats modulation frequency 1 kHz provides peak 30 mW/cm2. Low-intensity pulsed forms one currently available non-invasive healing-enhancing devices besides electro-stimulation (pulsed electro-magnetic field, PEMF). This modality leveraged enhance drug delivery, expedite injury recovery, improve muscle mobility, alleviate joint stiffness pain, bone fracture healing. Although embraced various medical disciplines, integration into standard dental practices still nascent stages, signifying unexplored frontier with potentially transformative implications. emerged attractive adjuvant therapy procedures, such orthodontic treatment maxillary sinus augmentation. Its appeal lies simplicity nature, positioning promising avenue clinical innovation. One particular area interest orthodontically induced inflammatory root resorption (OIIRR), oftenunavoidable outcome intervention, resulting permanent loss structure. Notably, OIIRR second common (RR), surpassed only related pulpal infection. Given high prevalence potential long-term consequences OIIRR, this literature review seeks evaluate efficacy approach, emphasis on assessing capacity reduce severity level significance. To conduct systematic review, comprehensive automated search was executed across multiple databases, including MEDLINE, Embase, PsycINFO, Web Knowledge, Scopus, CINAHL, LILACS, SciELO, Cochrane, PubMed, trials registries, 3ie, Google Scholar. Both forward backward citation tracking employed, encompassing studies published from database inception January 2009 April 2023. focused randomized controlled (RCTs) specifically evaluated effects low-intensity without restrictions publication date. A stringent selection criterion applied, demonstrating levels statistical significance were included. Ultimately, fourteen met inclusion criteria subjected further analysis. overall quality included rigorously assessed utilizing Grading Recommendations Assessment, Development, Evaluation (GRADE) approach. analysis revealed certain methodological limitations posed challenges drawing definitive conclusions evidence. Despite these constraints, offers invaluable insights can inform guide future research. Specifically, it delineates recommendations targeted populations, necessary appropriate measures, suitable study designs, essential infrastructure facilitate investigations. synthesis aims development field dentistry, thereby contributing improved patient outcomes.

Язык: Английский

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Advancing Postoperative Pain Management in Oral Cancer Patients: A Systematic Review

Pharmaceuticals, Год журнала: 2024, Номер 17(4), С. 542 - 542

Опубликована: Апрель 22, 2024

The goal of this review is to shed light on the management orofacial discomfort after a cancer diagnosis in head and neck region. A search was conducted PubMed, Scopus, Web Science identify studies postoperative pain control oral cancer. included open-access research, investigations into management, randomized clinical trials, retrospective studies, case-control prospective English-written full-text publications. Exclusion criteria animal studies; vitro off-topic reviews, case reports, letters, or comments; non-English language. Three reviewers independently accessed databases assigned quality rating chosen articles. explores patients; highlighting persistent opioid use; efficacy adjuvant drugs, such as gabapentin; multimodal approach. It emphasizes need for personalized recognizing individual perception tailoring interventions. Integrating pharmacological non-pharmacological strategies crucial comprehensive management. also serves guide future emphasizing standardized methodologies diverse participant populations.

Язык: Английский

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Structural and Color Alterations of Teeth following Orthodontic Debonding: A Systematic Review

Journal of Functional Biomaterials, Год журнала: 2024, Номер 15(5), С. 123 - 123

Опубликована: Май 10, 2024

Aim: The objective of this study was to explore the effects fixed orthodontic appliances on enamel structure by assessing microfractures, surface roughness, and alterations in color. Methods: This review followed Preferred Reporting Items for Systematic Reviews Meta-Analyses guidelines. A systematic search online databases conducted using keywords ‘enamel’ AND ‘orthodontic debonding’. Eligibility criteria included both vivo ex clinical trials human teeth. Results Discussion: total 14 relevant papers were analyzed. Various instruments techniques utilized across different studies assess color change, fractures. Conclusions: findings suggest that ceramic brackets may lead an increase fractures, particularly during bracket removal. roughness exhibits variability depending adhesive substance polishing methods used post-removal. Fixed could induce changes color, which be alleviated use nano-hydroxyapatite or specific techniques. Further research is necessary identify effective strategies managing these improving overall outcomes treatment.

Язык: Английский

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Effectiveness of ultrasonography in the diagnosis of temporomandibular joint disorders: A systematic review and meta‐analysis

Journal of Oral Rehabilitation, Год журнала: 2024, Номер unknown

Опубликована: Июль 18, 2024

Abstract Background Temporomandibular disorders (TMDs) pose diagnostic challenges, and selecting appropriate imaging modalities is crucial for accurate assessment. This study aimed to compare the accuracy efficacy of ultrasonography (US) magnetic resonance (MRI) in identifying TMDs. Methods A comprehensive meta‐analysis was conducted, including studies that compared US MRI TMJ disorder assessments. Fixed‐effects models were utilized calculate pooled odds ratios (ORs) relative risks (RRs) with 95% confidence intervals (CIs). Heterogeneity assessed using chi‐squared test I 2 statistic. Newcastle–Ottawa scale used assess methodological quality included. Results Six included, involving a total 281 participants. The demonstrated statistically somewhat better than disorders. summary OR 0.64 (95% CI: 0.46–0.90), RR 0.80 0.68–0.95). among low ( χ = 2.73, df 5, p .74; 0%). Demographic variables revealed variations sample size, gender ratio mean age across studies. Conclusion provides evidence may be more effective diagnosing However, limited by small number included demographic designs. Future research larger samples standardised protocols essential confirm strengthen these findings. Understanding will aid clinicians making informed decisions assessments patient management.

Язык: Английский

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Pregnancy related factors and temporomandibular disorders evaluated through the diagnostic criteria for temporomandibular disorders (DC/TMD) axis II: a cross sectional study

BMC Oral Health, Год журнала: 2024, Номер 24(1)

Опубликована: Фев. 13, 2024

Abstract Introduction Temporomandibular disorder (TMD) is a multifaceted condition impacting the chewing system, with its frequency varying across different age groups and showing higher incidence in women. The involvement of estrogen TMD has been examined due to presence receptors TMJ area. However, exact effect on complex. During pregnancy, marked by significant hormonal fluctuations, impact hypothesized but remains unclear inconsistent results from various studies. Methods In this cross-sectional study, we enrolled 32 pregnant women consecutively. We gathered information demographics, evaluations (using Graded Chronic Pain Scale, Jaw Functional Limitation Scale-20, Oral Behaviors Checklist), mental health assessments (including Patient Health Questionnaire-9, Questionnaire-15, Generalized Anxiety Disorder-7). employed descriptive statistics summarize continuous categorical data used t-tests chi-square tests for comparisons. also conducted multivariate linear regression, adjusted demographic factors, investigate correlations. Results study group mainly consisted aged 30–35 (40.6%) 25–30 (18.8%). Most participants had completed high school (50%) were married (71.9%). A notable association was found between younger (under 30) levels somatic symptoms ( p = 0.008) generalized anxiety 0.015). Women their second trimester showed lower severity 0.04). link observed depression symptom 0.01). no correlations other TMD-related aspects. Discussion Our identified associations psychosomatic psychological variables like pregnancy it notably failed establish clear relationship pregnancy-related factors temporomandibular disorders (TMD). More comprehensive studies larger participant pools are necessary further validate expand these findings.

Язык: Английский

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