Comparative- and Cost-effectiveness Research Determining the Optimal Intervention for Advancing Transgender Women with HIV to Full Viral Suppression (Text Me, Alexis!): Protocol for a Randomized Controlled Trial (Preprint) DOI Creative Commons
Cathy J. Reback,

Thomas R. Blue,

Ali Jalali

и другие.

JMIR Research Protocols, Год журнала: 2024, Номер unknown

Опубликована: Авг. 12, 2024

Many transgender women with HIV achieve suboptimal advancement through the Care Continuum, including poor health care usage, retention in medical care, and rates of viral suppression. These issues are exacerbated by comorbid conditions, such as substance use disorder, which is also associated reduced quality life, increased overdose deaths, usage high-cost services, engagement a street economy, cycles incarceration. Thus, it critical that efforts to End Epidemic include effective interventions link retain full This study builds on promising findings from our two Health Resources Services Administration-funded demonstration projects, The Alexis Project Text Me, Girl!, used peer navigation (PHN) SMS text messaging, respectively, for advancing Though effectiveness both has been established, their comparative effectiveness, required resources or costs, cost-effectiveness, heterogeneous effects subgroups, those have not evaluated. Given many negative personal public consequences untreated undertreated HIV, services frequently delivered resource-limited, community-based settings, comprehensive economic evaluation inform decisions stakeholders, providers, insurers, policy makers. Alexis! 3-arm randomized controlled trial. Participants (N=195) will be (1:1:1) into: PHN alone (n=65), messaging PHN+SMS (n=65). Using same time points Administration repeated-measures design assess participants at baseline, 3, 6, 12, 18 months post randomization. Over course 90 days, arm receive unlimited sessions; 270 theory-based messages (3 daily) targeted, tailored, personalized specifically HIV; combined message intervention. desired outcome suppression cost-effectiveness. Recruitment began April 10, 2024, first participant was enrolled 11, 2024. Data collection expected completed July 2027. Primary analyses begin immediately following conclusion follow-up evaluations. Transgender high-priority population reaching goals. Findings potential improve individual outcomes generating significant improvements among guiding service provision policy. DERR1-10.2196/65313.

Язык: Английский

Dynamic Network Analysis of Mental Health Symptoms Among Persons Living With HIV DOI Open Access
Shuyu Han, Xiaomeng Wang, Xin Xie

и другие.

Journal of Advanced Nursing, Год журнала: 2025, Номер unknown

Опубликована: Март 30, 2025

ABSTRACT Aim This study aims to develop dynamic networks and examine the longitudinal relationships of mental health symptoms among persons living with HIV (PLWH). Design A study. Methods We collected data between October 2022 December using Wenjuanxing (Questionnaire Star), an online survey platform. The tracked weekly across 10 sessions, involving 123 PLWH in Beijing, China. total 40 six dimensions (somatization symptoms, negative affect, cognitive processes, function, interpersonal communication social adaptation) were included symptom network, which consists temporal, contemporaneous between‐person networks. Results In temporal ‘feeling inferior others’ had largest in‐strength value, whereas ‘suicidal ideation’ exhibited out‐strength value. showed highest bridge strength, indicating it most connections other symptoms. Conclusions found that number predictors, up seven potentially triggering this particular symptom. Additionally, emerged as a powerful predictor, influencing greatest five dimensions. Impact Our enhances understanding sequential development consequences PLWH, may provide important basis for designing precise management interventions. Reporting Method was reported according STROBE checklist. Patient or Public Contribution No patient public contribution.

Язык: Английский

Процитировано

0
Addressing HIV and Substance Use Health Disparities among Racial/Ethnic Minority Individuals DOI Creative Commons

Jamie V. Saunt,

K. M. Kelley,

Corrilynn O. Hileman

и другие.

Current HIV/AIDS Reports, Год журнала: 2025, Номер 22(1)

Опубликована: Апрель 4, 2025

Язык: Английский

Процитировано

0
Comparative- and Cost-effectiveness Research Determining the Optimal Intervention for Advancing Transgender Women with HIV to Full Viral Suppression (Text Me, Alexis!) (Preprint) DOI Creative Commons
Cathy J. Reback,

Thomas R. Blue,

Ali Jalali

и другие.

Опубликована: Авг. 12, 2024

BACKGROUND Many trans women with HIV achieve suboptimal advancement through the Care Continuum, including poor healthcare utilization, retention in medical care, and rates of viral suppression. These issues are exacerbated by comorbid conditions, such as substance use disorder (SUD), which is also associated reduced quality-of-life, increased overdose deaths, utilization high-cost services, engagement a street economy, cycles incarceration. Thus, it critical that efforts to End Epidemic include effective interventions link retain care full OBJECTIVE This study builds on promising findings from our two Health Resources Services Administration (HRSA)-funded demonstration projects, The Alexis Project Text Me, Girl!, utilized Peer Navigation (PHN) SMS (i.e., text messaging), respectively, for advancing Though effectiveness both has been established, their comparative-effectiveness, required resources/costs, cost-effectiveness, heterogeneous effects subgroups, those SUD, have not evaluated. Given many negative personal public-health consequences untreated/undertreated HIV, services frequently delivered resource-limited, community-based settings, comprehensive economic evaluation inform decisions stakeholders, providers, insurers, policymakers. METHODS Alexis! three-arm randomized controlled trial (RCT). Participants (N = 195) will be (1:1:1) into: PHN alone (n 65), or PHN+SMS 65). Using same time points HRSA repeated-measures design assess participants at baseline, 3-, 6-, 12-, 18-months post-randomization. Over course 90-days, arm receive unlimited navigation sessions; 270 theory-based messages (three daily) targeted, tailored, personalized specifically HIV; combined intervention. desired outcome suppression cost effectiveness. RESULTS Recruitment began April 10, 2024, first participant was enrolled 11, 2024. Data collection expected completed July 2027. Primary analyses begin immediately following conclusion follow-up evaluations. CONCLUSIONS Trans high-priority population reaching goals. Findings potential improve individual health outcomes generating significant improvements among guiding service provision public policy.

Язык: Английский

Процитировано

0
Comparative- and Cost-effectiveness Research Determining the Optimal Intervention for Advancing Transgender Women with HIV to Full Viral Suppression (Text Me, Alexis!): Protocol for a Randomized Controlled Trial (Preprint) DOI Creative Commons
Cathy J. Reback,

Thomas R. Blue,

Ali Jalali

и другие.

JMIR Research Protocols, Год журнала: 2024, Номер unknown

Опубликована: Авг. 12, 2024

Many transgender women with HIV achieve suboptimal advancement through the Care Continuum, including poor health care usage, retention in medical care, and rates of viral suppression. These issues are exacerbated by comorbid conditions, such as substance use disorder, which is also associated reduced quality life, increased overdose deaths, usage high-cost services, engagement a street economy, cycles incarceration. Thus, it critical that efforts to End Epidemic include effective interventions link retain full This study builds on promising findings from our two Health Resources Services Administration-funded demonstration projects, The Alexis Project Text Me, Girl!, used peer navigation (PHN) SMS text messaging, respectively, for advancing Though effectiveness both has been established, their comparative effectiveness, required resources or costs, cost-effectiveness, heterogeneous effects subgroups, those have not evaluated. Given many negative personal public consequences untreated undertreated HIV, services frequently delivered resource-limited, community-based settings, comprehensive economic evaluation inform decisions stakeholders, providers, insurers, policy makers. Alexis! 3-arm randomized controlled trial. Participants (N=195) will be (1:1:1) into: PHN alone (n=65), messaging PHN+SMS (n=65). Using same time points Administration repeated-measures design assess participants at baseline, 3, 6, 12, 18 months post randomization. Over course 90 days, arm receive unlimited sessions; 270 theory-based messages (3 daily) targeted, tailored, personalized specifically HIV; combined message intervention. desired outcome suppression cost-effectiveness. Recruitment began April 10, 2024, first participant was enrolled 11, 2024. Data collection expected completed July 2027. Primary analyses begin immediately following conclusion follow-up evaluations. Transgender high-priority population reaching goals. Findings potential improve individual outcomes generating significant improvements among guiding service provision policy. DERR1-10.2196/65313.

Язык: Английский

Процитировано

0