Phytomedicine Plus, Год журнала: 2024, Номер unknown, С. 100723 - 100723
Опубликована: Дек. 1, 2024
Язык: Английский
Processes, Год журнала: 2025, Номер 13(1), С. 120 - 120
Опубликована: Янв. 5, 2025
This review provides an overview of recent developments in Citrus aurantium L. (sour or bitter orange), focusing on its bioactive compounds, innovative extraction techniques, and technological applications. C. is rich compounds such as flavonoids (naringin, hesperidin, kaempferol, quercetin), essential oils (β-pinene, limonene), vitamin C, which represents significant biological activities including antioxidant, antimicrobial, anti-inflammatory, anticancer effects. The discusses traditional methods, solvent hydrodistillation, alongside newer, eco-friendly approaches like ultrasound-assisted extraction, microwave-assisted supercritical fluid natural deep eutectic solvents. It also highlights cutting-edge molecular imprinting polymer-based enable the more efficient enrichment purification specific synephrine. Finally, examines diverse industrial applications these sectors foods, pharmaceuticals, cosmetics, while emphasizing growing need for sustainable technologies.
Язык: Английский
Процитировано
3
Molecules, Год журнала: 2025, Номер 30(2), С. 284 - 284
Опубликована: Янв. 13, 2025
Essential oils (EOs) are highly valued in the cosmetic and food industries for their diverse properties. However, traditional extraction methods often result low yields, inconsistent compositions, lengthy times, use of potentially harmful solvents. Natural deep eutectic solvents (NADES) have emerged as promising alternatives, offering advantages such higher efficiency, cost-effectiveness, biodegradability, tunable This review explores application NADES enhancing EO extraction, focusing on current methodologies, key insights, practical applications. It examines factors that influence with NADES, including optimization physicochemical properties, techniques, operational conditions, role sample pretreatment improving efficiency. Additionally, this covers chemical characterization biological activities EOs extracted using NADES. By providing a comprehensive overview, it highlights potential to improve suggests directions future research field.
Язык: Английский
Процитировано
0
Advances in Sample Preparation, Год журнала: 2025, Номер 13, С. 100149 - 100149
Опубликована: Янв. 16, 2025
Язык: Английский
Процитировано
0
Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology, Год журнала: 2025, Номер unknown, С. 1 - 14
Опубликована: Фев. 26, 2025
Язык: Английский
Процитировано
0
Industrial Crops and Products, Год журнала: 2025, Номер 227, С. 120783 - 120783
Опубликована: Март 12, 2025
Язык: Английский
Процитировано
0
Phytochemical Analysis, Год журнала: 2025, Номер unknown
Опубликована: Март 13, 2025
ABSTRACT Introduction Pine needles are a rich source of bioactive compounds, and there few reports on the extraction identification active substances in various types pine needles. Objectives The objective this study is to enhance efficiency yield needle essential oil by employing an innovative ultrasonic‐assisted salt‐out hydrodistillation technology. It also aims establish correlation between gas chromatography–mass spectrometry (GC–MS) electronic nose (E‐nose) distinguish oils from Cedrus deodara , Pinus thunbergii massoniana koraiensis . Methods Optimal conditions will be determined through dynamic curve fitting response surface analysis. Essential analyzed E‐nose GC–MS coupled with chemometrics. Radical‐scavenging effects ·OH, DPPH·, ABTS + radicals, antibacterial activity against Escherichia coli Staphylococcus aureus evaluated. Results were 100 min distillation, 7.762% sodium chloride, 9.596‐mL/g liquid material ratio, 170.155‐W ultrasonic power. yields 0.144%, 0.214%, 0.425%, 0.852% for C. P. respectively. identified 74 volatile components. PLS‐DA revealed nine key including α ‐Myrcene, ‐Pinene, ‐Phellandrene, Limonene, Caryophyllene, Bornyl acetate, β Germacrene D, Camphene. PCA data highlighted sample differences. All exhibited antioxidant activities, linked ‐pinene, D. Conclusion This introduces efficient methods characterization oils, providing foundation applications enhancing product quality global innovation industry.
Язык: Английский
Процитировано
0
Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 3 - 14
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Frontiers in Chemistry, Год журнала: 2025, Номер 13
Опубликована: Апрель 4, 2025
Background Ayurveda is an ancient Indian medicinal system that uses plants for their neuroprotective effects. claims the ( C. halicacabum ) leaves possess significant properties. Alzheimer’s characterized by accumulation of amyloid-β, acetylcholinesterase, and tau tangles interfere with neural transmission impair cognitive abilities. Objectives This study aimed to identify novel potential anti-Alzheimer phytoconstituents using in silico methods. Methods utilized Box–Behnken design within response surface methodology (RSM) optimize combine effects process variables, namely powder weight, solvent volume, extraction time, on microwave-assisted (MAE) leaves. The optimization revealed these along microwave usage, significantly influenced yield. ethanolic extract was examined gas chromatography-mass spectrometry (GC–MS) analysis, identified were further analyzed through computer-based simulations, including docking, absorption, distribution, metabolism, excretion, toxicity (ADMET) studies, assessment drug-likeness, molecular dynamics, LigPlot density functional theory (DFT) analysis. Results Gas (GC-MS) analysis 40 37 successfully characterized. Molecular docking dynamics simulations two lead compounds, acetic acid (dodecahydro-7-hydroxy-1,4b,8,8-tetramethyl-10-oxo-2(1H)-phenanthrenylidene)-,2-(dimethylamino)ethyl ester, [1R-(1. alpha)], 1-(2-hydroxyethoxy)-2-methyldodecane, which exhibited superior stability docked complex compared galantamine. Conclusion Based computational predictions observed pharmacological properties, findings suggest may have therapeutic against selected AD targets.
Язык: Английский
Процитировано
0
eFood, Год журнала: 2024, Номер 5(5)
Опубликована: Окт. 1, 2024
Abstract Genus Salvia is considered one of the largest genera family Lamiaceae with many recorded species and hybrids valuable biological importance. This study involved phytochemical characterization four (KNM23 ( S. fructicosa × officinalis ), KNM101 aramiensis KNM5 officinalis) KNM12 )) through measuring their total phenolic content (TPC) flavonoid (TFC) together profiling UPLC/MS n analysis followed by investigation antioxidant activities enzyme inhibitory potential different techniques. Hybrid KNM23 presented significantly high concentration both flavonoid, displaying a TPC 92.10 mg GAE/g TFC 50.85 RE/g. The resulted in tentative identification hundred eighty components from classes mainly flavonoids, acids, phenyl propanoids, tannins others. assay showed that hybrid KNM23, S . fruticosa , exhibited highest activity DPPH, ABTS, PBD assays, 436.38 mmol TE/g, 543.65 3.20 respectively. no inhibition AChE α ‐glucosidase. However, KMN12 demonstrated BChE tyrosinase 2.57 GALAE/g 12.91 KAE/g, Our results suggest can be as natural sources bioactive compounds development health‐promoting applications.
Язык: Английский
Процитировано
3
BMC Complementary Medicine and Therapies, Год журнала: 2024, Номер 24(1)
Опубликована: Апрель 12, 2024
Abstract Background Polyalthia suberosa (Roxb.) Thwaites (Annonaceae) is a medicinal plant that has been reported for its various pharmacological potentials, such as anti-inflammatory, analgesic, antioxidant, and neuropharmacological activities. This study aimed to analyze the leaf essential oils of P. (PSLO) collected in different seasons, evaluate acetylcholinesterase inhibitory activity, corroborate obtained results via in-silico molecular docking studies. Methods The seasons were analyzed separately by GC/MS. activity leaves oil was assessed colorimetric assay. In-silico studies elucidated virtual main compounds identified active sites human crystal structure. Results A total 125 where D-limonene (0.07 − 24.7%), α -copaene (2.25 15.49%), E- β -caryophyllene (5.17 14.42%), 24-noroleana-3,12-diene (12.92%), -pinene (0.14 8.59%), -humulene (2.49–6.9%) most abundant components. showed noteworthy influence collection season on chemical composition yield volatile oils. tested adequately inhibited enzyme with an IC 50 value 91.94 µg/mL. Additionally, unveiled palmitic acid, phytol, p -cymene, caryophyllene oxide demonstrated highest fitting scores within enzyme. Conclusions From these findings, it concluded should be evaluated food supplement enhancing memory.
Язык: Английский
Процитировано
2