Associations of healthy eating index 2020 and its components with non-alcoholic fatty liver disease in type 2 diabetes patients and the mediating roles of metabolic indicators: NHANES 2007–2018 DOI Creative Commons

Jingxiong Chen,

Haizhou Diao,

Yuling Zhang

и другие.

Frontiers in Nutrition, Год журнала: 2025, Номер 12

Опубликована: Апрель 9, 2025

Background Non-alcoholic fatty liver disease (NAFLD) represents a major public health issue, especially among individuals diagnosed with Type 2 diabetes mellitus (T2DM), where its prevalence can reach up to 70%. This research examines the relationship between Healthy Eating Index 2020 (HEI-2020) and individual components occurrence of NAFLD in T2DM patients, while also investigating potential mediating effects various metabolic indicators. Methods Data from National Health Nutrition Examination Survey (NHANES) spanning 2007 2018 were utilized. cross-section study included 1,770 who divided into non-NAFLD groups using Fatty Liver as diagnostic tool. The HEI-2020, which assesses diet quality, was computed based on 24-h dietary recall data. Key indicators such triglyceride-glucose (TyG) index, score (MS), mean arterial pressure, uric acid levels, total cholesterol evaluated. Results findings indicated that higher HEI-2020 scores associated lower likelihood (odds ratio 0.978, 95% confidence interval: 0.959–0.998), strongest inverse associations observed top quartiles quality. Whole fruits, greens beans, saturated fat crucial factors. Mediation analysis demonstrated TyG index MS accounted for 5.11 36.94% NAFLD, respectively. Conclusion Greater adherence is partially this association. Enhancing particularly by increasing consumption whole fruits reducing intake, may be important managing function vulnerable population.

Язык: Английский

Associations of healthy eating index 2020 and its components with non-alcoholic fatty liver disease in type 2 diabetes patients and the mediating roles of metabolic indicators: NHANES 2007–2018 DOI Creative Commons

Jingxiong Chen,

Haizhou Diao,

Yuling Zhang

и другие.

Frontiers in Nutrition, Год журнала: 2025, Номер 12

Опубликована: Апрель 9, 2025

Background Non-alcoholic fatty liver disease (NAFLD) represents a major public health issue, especially among individuals diagnosed with Type 2 diabetes mellitus (T2DM), where its prevalence can reach up to 70%. This research examines the relationship between Healthy Eating Index 2020 (HEI-2020) and individual components occurrence of NAFLD in T2DM patients, while also investigating potential mediating effects various metabolic indicators. Methods Data from National Health Nutrition Examination Survey (NHANES) spanning 2007 2018 were utilized. cross-section study included 1,770 who divided into non-NAFLD groups using Fatty Liver as diagnostic tool. The HEI-2020, which assesses diet quality, was computed based on 24-h dietary recall data. Key indicators such triglyceride-glucose (TyG) index, score (MS), mean arterial pressure, uric acid levels, total cholesterol evaluated. Results findings indicated that higher HEI-2020 scores associated lower likelihood (odds ratio 0.978, 95% confidence interval: 0.959–0.998), strongest inverse associations observed top quartiles quality. Whole fruits, greens beans, saturated fat crucial factors. Mediation analysis demonstrated TyG index MS accounted for 5.11 36.94% NAFLD, respectively. Conclusion Greater adherence is partially this association. Enhancing particularly by increasing consumption whole fruits reducing intake, may be important managing function vulnerable population.

Язык: Английский

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