Nanotechnology for a Sustainable Future: Addressing Global Challenges with the International Network4Sustainable Nanotechnology

ACS Nano, Год журнала: 2021, Номер 15(12), С. 18608 - 18623

Опубликована: Дек. 15, 2021

Nanotechnology has important roles to play in international efforts sustainability. We discuss how current and future capabilities nanotechnology align with support the United Nations' Sustainable Development Goals. argue that, as a field, we can accelerate progress toward these goals both directly through technological solutions our special interdisciplinary skills communication tackling difficult challenges. of targeting solutions, technology translation, circular economy, number examples from national around world reaching goals. have formed network leading nanocenters address challenges globally seek recruit others join us.

Язык: Английский

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Design Challenges in Polymeric Scaffolds for Tissue Engineering

Frontiers in Bioengineering and Biotechnology, Год журнала: 2021, Номер 9

Опубликована: Июнь 14, 2021

Numerous surgical procedures are daily performed worldwide to replace and repair damaged tissue. Tissue engineering is the field devoted regeneration of tissue through incorporation cells in biocompatible biodegradable porous constructs, known as scaffolds. The scaffolds act host biomaterials incubating cells, guiding their attachment, growth, differentiation, proliferation, phenotype, migration for development new Furthermore, cellular behavior fate bound biodegradation scaffold during generation. This article provides a critical appraisal how key biomaterial parameters, such structure architecture, biochemistry, mechanical behavior, biodegradability, impart needed morphological, structural, biochemical cues eliciting cell various applications. Particular emphasis given on specific attributes pertaining skin brain generation, where further progress (skin) or research at relatively primitive stage (brain), enumeration some most important challenges regarding constructs engineering.

Язык: Английский

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Microfluidic chips: recent advances, critical strategies in design, applications and future perspectives

Microfluidics and Nanofluidics, Год журнала: 2021, Номер 25(12)

Опубликована: Окт. 26, 2021

Язык: Английский

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A critical review on quantum dots: From synthesis toward applications in electrochemical biosensors for determination of disease-related biomolecules

Talanta, Год журнала: 2020, Номер 224, С. 121828 - 121828

Опубликована: Ноя. 9, 2020

Язык: Английский

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Tumor-on-a-chip: from bioinspired design to biomedical application

Microsystems & Nanoengineering, Год журнала: 2021, Номер 7(1)

Опубликована: Июнь 21, 2021

Cancer is one of the leading causes human death, despite enormous efforts to explore cancer biology and develop anticancer therapies. The main challenges in research are establishing an efficient tumor microenvironment vitro exploring means for screening drugs reveal nature treatments. possesses human-specific biophysical biochemical factors that difficult recapitulate conventional planar cell models vivo animal models. Therefore, model limitations have hindered translation basic findings clinical applications. In this review, we introduce recent progress tumor-on-a-chip devices research, medicine assessment, biomedical applications detail. emerging platforms integrating 3D culture, microfluidic technology, tissue engineering successfully mimicked pivotal structural functional characteristics microenvironment. advances studies detailed analyzed review. This review should be valuable further understanding mechanisms evolution process, drugs, developing therapies, it addresses potential opportunities predicting drug treatment.

Язык: Английский

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Microfluidic organ-on-a-chip models of human liver tissue

Acta Biomaterialia, Год журнала: 2020, Номер 116, С. 67 - 83

Опубликована: Сен. 2, 2020

Язык: Английский

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Precision Medicine: Disease Subtyping and Tailored Treatment

Cancers, Год журнала: 2023, Номер 15(15), С. 3837 - 3837

Опубликована: Июль 28, 2023

The genomics-based concept of precision medicine began to emerge following the completion Human Genome Project. In contrast evidence-based medicine, will allow doctors and scientists tailor treatment different subpopulations patients who differ in their susceptibility specific diseases or responsiveness therapies. current model was proposed precisely classify into subgroups sharing a common biological basis for more effective tailored achieve improved outcomes. Precision has become term that symbolizes new age medicine. this review, we examine history, development, future perspective We also discuss concepts, principles, tools, applications related fields. our view, work, two essential objectives need be achieved. First, classified various subtypes. Second, targeted therapies must available each disease subtype. Therefore, focused review on progress meeting these objectives.

Язык: Английский

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Pseudomonas aeruginosa biofilms and their partners in crime

Biotechnology Advances, Год журнала: 2021, Номер 49, С. 107734 - 107734

Опубликована: Март 27, 2021

Pseudomonas aeruginosa biofilms and the capacity of bacterium to coexist interact with a broad range microorganisms have substantial clinical impact. This review focuses on main traits P. biofilms, such as structural composition regulatory networks involved, placing particular emphasis challenges they represent in terms antimicrobial susceptibility biofilm infection clearance. Furthermore, ability grow together other is significant pathogenic attribute relevance; hence, microbial interactions are especially highlighted detailed throughout this review. article also explores infections caused by single polymicrobial current models used recreate them under laboratory conditions. Finally, antibiofilm strategies developed against mono multispecies at end

Язык: Английский

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Organ-On-A-Chip: A Survey of Technical Results and Problems

Frontiers in Bioengineering and Biotechnology, Год журнала: 2022, Номер 10

Опубликована: Фев. 10, 2022

Organ-on-a-chip (OoC), also known as micro physiological systems or "tissue chips" have attracted substantial interest in recent years due to their numerous applications, especially precision medicine, drug development and screening. devices can replicate key aspects of human physiology, providing insights into the studied organ function disease pathophysiology. Moreover, these accurately be used discovery for personalized medicine. These present useful substitutes traditional preclinical cell culture methods reduce use

Язык: Английский

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Impactful Digital Twin in the Healthcare Revolution

Big Data and Cognitive Computing, Год журнала: 2022, Номер 6(3), С. 83 - 83

Опубликована: Авг. 8, 2022

Over the last few decades, our digitally expanding world has experienced another significant digitalization boost because of COVID-19 pandemic. Digital transformations are changing every aspect this world. New technological innovations springing up continuously, attracting increasing attention and investments. twin, one highest trending technologies recent years, is now joining forces with healthcare sector, which been under spotlight since outbreak COVID-19. This paper sets out to promote a better understanding digital twin technology, clarify some common misconceptions, review current trajectory applications in healthcare. Furthermore, functionalities different life stages summarized context model Following Internet Things as service concept twining supporting Industry 4.0, we propose paradigm twinning everything service, groups physical entities also clarified for clear reference architecture research discusses value technology healthcare, well challenges insights future research.

Язык: Английский

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