Disparities by Social Determinants of Health: Links Between Long COVID and Cardiovascular Disease

Canadian Journal of Cardiology, Год журнала: 2024, Номер 40(6), С. 1123 - 1134

Опубликована: Фев. 28, 2024

Long COVID has been defined by World Health Organization as "continuation or development of new symptoms 3 months after the initial SARS-CoV-2 infection, with these lasting for at least 2 no other explanation". Cardiovascular disease is implicated a risk factor, concomitant condition and consequence COVID. As well heterogeneity in definition, presentation likely underlying pathophysiology COVID, disparities social determinants health, extensively studied described cardiovascular disease, have observed three ways. First, long-term conditions, such its factors, are associated incidence severity previously socioeconomic factors important exacerbating Second, management COVID-19 may themselves lead to distal Third, there way that diagnosed, managed prevented. Together, age, sex, deprivation ethnicity far-reaching implications this post-viral syndrome across spectrum. There similarities differences compared disease. Some fact, inequalities, i.e. rather than simply variations, they represent injustices costs individuals, communities economies. In review current literature, I consider opportunities prevent, least, attenuate special challenges research, clinical practice, public health policy which evolving.

Язык: Английский

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Gender Disparities in Neurological Symptoms of Long-COVID: A systematic review and meta-analysis

Neuroepidemiology, Год журнала: 2024, Номер unknown, С. 1 - 15

Опубликована: Авг. 19, 2024

Background: Female gender is a known risk factor for long COVID. With the increasing number of COVID-19 cases, corresponding survivors also expected to rise. To best our knowledge, no systematic review has specifically addressed differences in neurological symptoms Methods: We included studies on female individuals who presented with specific at least 12 weeks after confirmed diagnosis from PubMed, Central, Scopus, and Web Science. The search limit was put January 2020 until June 15, 2024. excluded that did not provide sex-specific outcome data, those English, case reports, series, articles Results: A total 5,632 eligible were identified. This article provides relevant information involving 6,849 patients, which 3,414 female. sample size ranged 70 2,856, maximum follow-up period 18 months. earliest publication date September 16, 2021, while latest 11, following had significant difference ratio (RR) gender: fatigue RR 1.40 (95% confidence interval [CI]: 1.22–1.60, p < 0.001), headache 1.37 CI: 1.12–1.67, = 0.002), brain-fog 1.38 CI 1.08–1.76, 0.011) depression 1.49 1.2–1.86, anosmia 1.61 1.36–1.90, 0.001). High heterogenicity found fatigue, brain fog, anxiety due diverse methodologies employed studies. Conclusion: Our findings suggest women are higher long-COVID symptoms, including headaches, depression, anosmia, compared men. prevalence these decreases 1 year, based limited data small available beyond this period.

Язык: Английский

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Identifying people with post-COVID condition using linked, population-based administrative health data from Manitoba, Canada: prevalence and predictors in a cohort of COVID-positive individuals

BMJ Open, Год журнала: 2025, Номер 15(1), С. e087920 - e087920

Опубликована: Янв. 1, 2025

Objective Many individuals exposed to SARS-CoV-2 experience long-term symptoms as part of a syndrome called post-COVID condition (PCC). Research on PCC is still emerging but urgently needed support diagnosis, clinical treatment guidelines and health system resource allocation. In this study, we developed method identify cases using administrative data report prevalence predictive factors in Manitoba, Canada. Design Cohort study. Setting Participants All Manitobans who tested positive for during population-wide PCR testing from March 2020 December 2021 (n=66 365) were subsequently deemed have based International Classification Disease-9/10 diagnostic codes prescription drug (n=11 316). Additional identified modelling assess patterns service use, including physician visits, emergency department visits hospitalisation any reason (n=4155). Outcomes We measured % among with tests associated by calculating odds ratios 95% confidence intervals, adjusted sociodemographic characteristics (aOR). Results Among 66 365 tests, 15 471 (23%) having PCC. Being female (aOR 1.64, CI 1.58 1.71), being age 60–79 1.33, 1.25 1.41) or 80+ 1.62, 1.46 1.80), hospitalised within 14 days COVID-19 infection 1.95, 1.80 2.10) Charlson Comorbidity Index 1+ 1.78 2.14) Receiving doses the vaccine (one dose, aOR 0.80, 0.74 0.86; two doses, 0.29, 0.22 0.31) decreased Conclusions This data-driven approach expands our understanding epidemiology may be applied other jurisdictions population-based data. The study provides additional insights into risk protective inform planning delivery.

Язык: Английский

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Lessons Learned From Characterizing Long COVID Among US Medicare Beneficiaries

Pharmacoepidemiology and Drug Safety, Год журнала: 2025, Номер 34(2)

Опубликована: Янв. 22, 2025

To characterize long-term effects of COVID-19 among older adults (aged ≥ 65 years). This retrospective descriptive study utilized Medicare Fee-for-Service beneficiaries' claims to post-COVID condition diagnosis code usage, long COVID (defined as diagnoses made 28 days after an initial diagnosis) incidence, patient demographics, and concurrent diagnoses. During April 1, 2020 May 21, 2022, 193 691 (0.6%) 31 847 927 beneficiaries were diagnosed with conditions using ICD-10-CM codes U09.9 B94.8, regardless prior diagnosis. Post-COVID rate was higher nursing home residents (18.7 per 1000 person-years) than community-dwelling (2.8). Among a diagnosis, 17.5% did not have any U07.1 recorded. there no significant sex, age, or race/ethnicity differences between those (i.e., COVID) without conditions. Certain myopathies interstitial pulmonary disease disproportionately present concurrently compared COVID-19. In this large 32 million beneficiaries, we found approximately 194 000 residents, highlighting the substantial burden in vulnerable population. Community-dwelling less likely seek medical care for events which may suggest severity respiratory detection these populations. Long risk infection be similar across demographic groups.

Язык: Английский

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Prevalence of Food and Housing Insecurity among Direct Support Professionals in New York

SSRN Electronic Journal, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Development of an expectation management intervention for patients with Long COVID: A focus group study with affected patients

PLoS ONE, Год журнала: 2025, Номер 20(2), С. e0317905 - e0317905

Опубликована: Фев. 3, 2025

Background A significant number of individuals who have contracted SARS-CoV-2 report persistent somatic symptoms after the infection has resolved. Evidence-based treatment options for Long COVID are lacking to date. To ensure that an expectation management intervention, designed research project SOMA.COV, addresses relevant patient needs as well promote acceptance and adherence, a participatory approach was chosen. Objective The aim present study explore wishes patients with regarding preliminary version intervention thereby inform further development manual. Methods Twenty-two affected by participated in one four focus groups June July 2023. Participants were presented draft content four-session intervention. Feedback audio-recorded, transcribed, analyzed using thematic analysis. Results Thirteen themes relating main components manual developed. Large parts received overall positive feedback, including psychoeducation on biopsychosocial etiology condition, elements cognitive restructuring, imagination exercise. Patients’ response vicious circle fear behavior change exercise mixed. Modifications made patients’ feedback. Conclusion Patients provided feedback while also highlighting important adaptations necessary this group. results informed finalization within SOMA.COV project, which investigates effectiveness three-armed randomized controlled trial.

Язык: Английский

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Post-COVID-19 functional status in socioeconomically vulnerable neighborhoods attended in primary health care in two Brazilian cities: a cross-sectional study

BMC Infectious Diseases, Год журнала: 2025, Номер 25(1)

Опубликована: Март 12, 2025

The prolonged effects of COVID-19 present social costs and pose challenges to public health infrastructure, necessitating the implementation policies for comprehensive post-COVID-19 care. This study aimed assess post-COVID functional status associated sociodemographic factors inequalities among residents socioeconomically vulnerable neighborhoods who attended primary care in two Brazilian cities. A cross-sectional was conducted from July 2022 2023 Salvador Rio de Janeiro. We included participants sought tests services, had previously contracted COVID-19, completed scale. Post-COVID syndrome classified as none, negligible/slight, or moderate/severe. Sociodemographic characteristics, conditions, access services were analyzed explanatory variables. Descriptive bivariate analyses performed. Using multinomial logistic regression, we estimated adjusted odds ratios (aORs) their 95% confidence intervals (95%CIs). Among 3,067 participants, overall prevalence limitations 34.6% (26.7% 7.9% reporting negligible/slight moderate/severe, respectively). following variables with moderate/severe status: living households fewer rooms (aOR = 1.66, 95%CI: 1.23-2.24), female gender 1.57, 1.14-2.16), older age 1.02, 1.01-1.03), self-reported diabetes mellitus 1.78, 1.17-2.69), respiratory diseases 2.59, 1.56-4.29), having more times 1.15-2.14), not a medical appointment last 12 months 1.70, 1.24-2.33), difficulty accessing testing 1.63, 1.05-2.52), experience discrimination 2.85, 1.87-4.35). Our findings indicate varying degrees limitation have recovered COVID-19. People live homes rooms, are female, older, pre-existing diseases, been reinfected those experienced at higher chance developing syndrome.

Язык: Английский

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Risk, determinants, and persistence of long-COVID in a population-based cohort study in Catalonia

BMC Medicine, Год журнала: 2025, Номер 23(1)

Опубликована: Март 14, 2025

Long-COVID has mostly been investigated in clinical settings. We aimed to assess the risk, subtypes, persistence, and determinants of long-COVID a prospective population-based study adults with history SARS-CoV-2 infection Catalonia. examined 2764 infected individuals from cohort (COVICAT) established before pandemic followed up three times across (2020, 2021, 2023). assessed immunoglobulin (Ig)G levels against SARS-CoV-2, clinical, vaccination, sociodemographic, lifestyle factors. risk subtypes were defined based on participant-reported symptoms electronic health records. identified total 647 cases compared them 2117 without condition. Between 2021 2023, 23% subjects developed symptoms. In 56% persisted for 2 years. presented clinically mild neuromuscular, respiratory, severe multi-organ. The latter was associated persistent long-COVID. Risk higher among females, participants under 50 years, low socioeconomic status, COVID-19 infection, elevated pre-vaccination IgG levels, obesity, prior chronic disease, particularly asthma/chronic obstructive pulmonary disease mental conditions. A lower pre-infection after omicron became dominant variant, physical activity sleeping 6–8 h. Vaccination during 3 months post-infection also protective years half cases, influenced by multiple

Язык: Английский

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Exploring Long Covid Prevalence and Patient Uncertainty by Sociodemographic Characteristics Using GP Patient Survey Data

Health Expectations, Год журнала: 2025, Номер 28(2)

Опубликована: Март 17, 2025

ABSTRACT Background The high global burden of Long Covid (LC) has significant implications for population well‐being, health care, social care and national economies. Aim To explore associations between patient sociodemographic characteristics with two outcomes: having LC expressing uncertainty about LC, as described by general practice (GP) survey respondents. Design Setting Analysis GP Patient Survey (England), a random sample 759,149 patients aged 16 years+ registered in England (2023). Method Multivariable logistic regression modelling comparing those without who were unsure relation to characteristics. Results 4.8% respondents reported 9.1% unsure. Significant adjusted indicating higher risk included age (highest odds 35−54 years), sex (females), ethnicity (White Gypsy/Irish Traveller, mixed/multiple ethnic groups), sexual orientation (gay/lesbian or bisexual), living deprived area, being carer parent long‐term condition (LTC). Those ≤ 25 years, males, non‐binary, heterosexual, not parents carers, from other White, Indian, Bangladeshi, Chinese, Black Arab backgrounds, former current smokers, no defined LTC more likely analysis be compared answering ‘yes’. Conclusion There is an unequal distribution England, the prevalent minoritised disadvantaged groups. are also levels LC. Improved awareness needed amongst professionals ensure most vulnerable society identified provided support. Public Contribution builds on previous studies co‐created people lived experience. A public contributor advised discussions dissemination towards optimal impact this study's findings. Study findings will inform next phases research which questions design partners. How This Fits In there prevalence Covid, COVID‐19 infection‐induced chronic that can limit daily activities significantly. ill unequal, groups experiencing prevalence. study adds further evidence inequality but reveals whether they have than confident it, certain already uncertain if condition. Findings underline need greater professionals, diagnosis, treatment support better distributed according need.

Язык: Английский

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Sex-related differences in the association between migraine, COVID-19, and long COVID: a population-based cohort

Frontiers in Neurology, Год журнала: 2025, Номер 16

Опубликована: Март 21, 2025

Background Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, placed unprecedented pressure on public health systems due to its mortality and global panic—and later long COVID challenges. One of these symptoms, headache, often resembles migraine-like features. Migraine shares similarities with COVID-19 COVID, yet influence sex is understudied. Our primary objective was study interrelationship between migraine prevalence, while considering differences. The secondary examine how symptoms (headache, anosmia, memory, concentration problems) affect males females without migraine. Methods All analyses were conducted using Lifelines, a prospective cohort in northern Netherlands. Baseline characteristics (2006–2014), self-reported diagnoses (until 2021), questionnaires (2020–2022) collected. Logistic regression association lifetime current infections adjusting for age, sex, diet, educational attainment, activity, smoking. Descriptive sex-stratified symptoms. Results A total 150,507 individuals included, which 29,680 (19.7%) reported 120,827 (80.3%) not. 1,867 [6.3% migraine, 44.0 years (IQR 36.1–50.3)] 6,797 [5.6% 44.4 35.3–52.2)] be infected. majority consisted (77.0% those vs. 54.0% migraine). adjusted odds having 6.3% higher among (a history of) compared logistic model (OR = 1.06, 95% CI 1.01–1.12). slightly OR observed 1.08, 1.02–1.15), not apparent 1.00, 0.88–1.12). Secondary revealed that both COVID-19, particular, most frequently bothered concentration, memory problems. Individuals none diseases least bothered. Conclusions especially females, are more likely report and/or contract COVID-19. Those conditions frequently, suggesting shared vulnerability or pathophysiology. This may indicate need clinical surveillance patients recovering from

Язык: Английский

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