The application of exosomes in skin photoaging

Deleted Journal, Год журнала: 2025, Номер unknown, С. 1 - 13

Опубликована: Янв. 20, 2025

Skin photoaging, primarily caused by chronic ultraviolet (UV) exposure, leads to the degradation of extracellular matrix components, increased oxidative stress, and diminished cellular repair capacity, contributing visible signs aging such as wrinkles, pigmentation, loss skin elasticity. In recent years, exosomes, small vesicles involved in intercellular communication, have emerged a promising therapeutic tool rejuvenation management photoaging. Exosomes derived from various cell types, including mesenchymal stem cells (MSCs), keratinocytes, fibroblasts, carry bioactive molecules proteins, lipids, RNAs, growth factors that can modulate homeostasis, promote collagen synthesis, enhance mechanisms. This review aims explore molecular mechanisms which exosomes influence their potential applications regenerative dermatology, challenges associated with clinical translation. Furthermore, we discuss future prospects exosome-based therapies development novel anti-aging treatments, emphasizing safety, efficacy, delivery systems.

Язык: Английский

Smart Self-Assembled Peptide-based Hydrogels: Mechanism, Design and Biomedical Applications

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114704 - 114704

Опубликована: Апрель 1, 2025

Язык: Английский