Platelet-rich plasma alleviates skin photoaging by activating autophagy and inhibiting inflammasome formation

Naunyn-Schmiedeberg s Archives of Pharmacology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

Язык: Английский

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Mechanism underlying the involvement of CXCR4/CXCL12 in diabetic wound healing and prospects for responsive hydrogel-loaded CXCR4 formulations

Frontiers in Pharmacology, Год журнала: 2025, Номер 16

Опубликована: Апрель 16, 2025

Diabetes mellitus is a prevalent chronic disease, often leading to complications, with wounds being among the most challenging. Impairment of CXCR4/CXCL12 signaling pathway, which plays key role in cell mobilization, migration, and angiogenesis, significantly hampers wound healing process diabetic patients. Modulation this pathway using CXCR4-targeted agents has shown promise restoring repair capabilities. Additionally, development responsive hydrogels capable adapting external stimuli offers powerful platform for drug delivery management. These hydrogels, when loaded CXCR4 agonists or antagonists, enable controlled release real-time therapeutic modulation. Integrating such existing strategies may provide an innovative effective solution overcoming challenges associated treatment.

Язык: Английский

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A novel antioxidant and anti-inflammatory carboxymethylcellulose/chitosan hydrogel loaded with cannabidiol promotes the healing of radiation-combined wound skin injury in the 60Co γ-irradiated mice

Phytomedicine, Год журнала: 2025, Номер unknown, С. 156790 - 156790

Опубликована: Апрель 1, 2025

Язык: Английский

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Exploration of the Topical Nanoemulgel Bearing with Ferulic Acid and Essential Oil for Diabetic Wound Healing

Pathophysiology, Год журнала: 2024, Номер 31(4), С. 680 - 698

Опубликована: Ноя. 25, 2024

To investigate the anti-inflammatory, antioxidant, and diabetic wound healing properties of novel topical formulation [Ferulic acid-loaded nanoemulgel (DLMGO-G)].

Язык: Английский

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