Advanced Science, Год журнала: 2025, Номер unknown

Опубликована: Май 23, 2025

Abstract Microfluidics can achieve the spatiotemporal manipulation of particles and cells in microscale fluids, but highly relies on accuracy pumping systems. To overcome this issue, a pump‐free, hydraulic‐amplification oscillatory microfluidic (PHOMF) device is presented, which be actuated by fingers to handle within microchannel. The PHOMF has module for pressure transfer soft microchannel generation flows. This made possible periodic finger‐driven liquid causes deform then drives reciprocating flow fluid volumes In flow, single‐line focusing driven spatially accumulated inertial elastic lift forces. particle elasto‐inertial theory been revealed. demonstrate system's practicality, utilized early observation platelet clots (3 min) rapid staining cancer (8 min). provides miniaturized, inexpensive, efficient detection tool lab‐on‐a‐chip, potential become mass‐produced, widely available, convenient disease product.

Язык: Английский