Research Square (Research Square),
Год журнала:
2023,
Номер
unknown
Опубликована: Окт. 10, 2023
Abstract
Background
Perioperative
analgesia
can
improve
the
quality
of
postoperative
recovery
in
thoracoscopic
patients.
Nevertheless,
traditional
analgesic
effects
are
not
ideal.
Therefore,
we
intend
to
afford
a
fresh
approach
managing
pain
patients
by
dint
probe
into
efficacy
and
safety
local
ozone
injection.
Methods
The
sequence
marked
87
subject
downwards
video-assisted
lobectomy,
divided
group
(n
=
44)
control
43).
Primary
observation
indexes
included
resting
visual
analog
scale
at
6
h,
24
48
72
h
as
well
three-month
simplified
McGill
questionnaire.
statistical
software
SPSS
20.0
was
used
analyse
similarity
dissimilarity
data.
Results
Visual
Analogue
Scale
scores
(6
h)
after
surgery
were
allegedly
lower
than
those
(p
<
0.01).
However,
there
no
significant
differences
sensory
item
score
affective
Pain
Rating
Index,
score,
or
Present
Intensity
between
two
groups
third
month
>
0.05).
Conclusions
Local
injection
for
pulmonary
lobectomy
effectively
lowers
scores,
facilitates
incision
healing,
reduces
acute
adverse
reactions,
enhances
patients'
short-term
life
surgery.
through
surgical
is
practical,
safe,
feasible
relief
undergoing
lobectomy.
Trial
Registration
ChiCTR2000037691(http://www.chictr.org.cn/showproj.aspx?proj=59038)registered
on
30/8/2020
Anaesthesia,
Год журнала:
2021,
Номер
77(3), С. 311 - 325
Опубликована: Ноя. 5, 2021
Summary
Video‐assisted
thoracoscopic
surgery
has
become
increasingly
popular
due
to
faster
recovery
times
and
reduced
postoperative
pain
compared
with
thoracotomy.
However,
analgesic
regimens
for
video‐assisted
vary
significantly.
The
goal
of
this
systematic
review
was
evaluate
the
available
literature
develop
recommendations
optimal
management
after
surgery.
A
undertaken
using
procedure‐specific
(PROSPECT)
methodology.
Randomised
controlled
trials
published
in
English
language,
between
January
2010
2021
assessing
effect
analgesic,
anaesthetic
or
surgical
interventions
were
identified.
We
retrieved
1070
studies
which
69
randomised
two
reviews
met
inclusion
criteria.
recommend
administration
basic
analgesia
including
paracetamol
non‐steroidal
anti‐inflammatory
drugs
cyclo‐oxygenase‐2‐specific
inhibitors
pre‐operatively
intra‐operatively
continued
postoperatively.
Intra‐operative
intravenous
dexmedetomidine
infusion
may
be
used,
specifically
when
regional
techniques
could
not
given.
In
addition,
a
paravertebral
block
erector
spinae
plane
is
recommended
as
first‐choice
option.
serratus
anterior
also
administered
second‐choice
Opioids
should
reserved
rescue
analgesics
period.
Insights into Imaging,
Год журнала:
2022,
Номер
13(1)
Опубликована: Янв. 28, 2022
To
explore
the
effect
of
a
single
preoperative
ultrasound-guided
thoracic
paravertebral
nerve
block
(TPVB)
and
erector
spinae
plane
(ESPB)
for
perioperative
analgesia
in
thoracoscopic
pulmonary
lobectomy.Seventy-two
patients
aged
40-70
years
who
underwent
lobectomy
under
general
anesthesia
were
enrolled
randomly
divided
into
control
group
(Group
C),
TPVB
T)
ESPB
E).
The
primary
observation
indicators
included
visual
analogue
scale
(VAS)
at
1,
6,
12,
24,
48
h
postoperatively
rest
with
cough.
secondary
intraoperative
sufentanil
consumption,
awakening
time
extubation
time,
consumption
analgesic
pump,
flurbiprofen
ester
remedial
within
after
surgery
incidence
postoperative
adverse
events.The
lower
groups
T
E
than
those
C
(p
<
0.05).
Patients
had
VAS
scores
cough
12
same
points
1
6
coughing
status
0.05).The
could
both
reduce
pain
score
dose
analgesics.
Pain and Therapy,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 22, 2025
Postoperative
analgesia
in
thoracoscopic
lung
resection
is
crucial,
with
several
nerve
block
techniques—including
thoracic
epidural
anesthesia
(TEA),
paravertebral
(PVB),
erector
spinae
plane
(ESPB),
intercostal
(INB),
and
serratus
anterior
(SAPB)—commonly
employed.
However,
there
remains
ongoing
debate
regarding
the
optimal
technique.
To
evaluate
compare
effectiveness
of
these
methods,
a
systematic
review
was
conducted
across
multiple
databases,
including
PubMed,
Embase,
Web
Science,
Cochrane
Library,
identifying
relevant
randomized
clinical
trials
(RCTs).
A
Bayesian
network
meta-analysis
performed
to
assess
postoperative
pain
management,
subgroup
analyses
meta-regression
examine
key
factors
influencing
outcomes,
such
as
risk
bias,
continuous
catheter
analgesia,
patient-controlled
(PCA).
The
results
revealed
that
for
12-h
resting
visual
analog
scale
(VAS)
scores,
surface
under
cumulative
ranking
curve
(SUCRA)
TEA
>
PVB
ESPB
control
INB
SAPB,
whereas
at
24
h,
it
shifted
SAPB.
For
coughing
VAS
ranked
highest,
followed
by
PVB,
ESPB,
control.
At
TEA,
INB,
inconsistency
test
showed
good
consistency,
minimal
publication
neither
study
quality
nor
local
anesthetic
infiltration
incision
site
significantly
impacted
outcomes.
Excluding
studies
without
PCA
did
not
change
SUCRA
rankings.
consistently
highest
24-h
scores.
Clustered
plots
indicated
were
most
suitable
techniques
analgesia.
emerged
analgesic
resection.
While
superior
efficacy,
offered
fewer
side
effects,
providing
safety
advantage.
considered
less
due
its
excessive
effects.
Interdisciplinary CardioVascular and Thoracic Surgery,
Год журнала:
2023,
Номер
36(1)
Опубликована: Янв. 1, 2023
Pain
after
thoracoscopic
surgery
may
increase
the
incidence
of
postoperative
complications
and
impair
recovery.
Guidelines
lack
consensus
regarding
analgesia.
We
performed
a
systematic
review
meta-analysis
to
determine
mean
pain
scores
different
analgesic
techniques
(thoracic
epidural
analgesia,
continuous
or
single-shot
unilateral
regional
analgesia
only
systemic
analgesia)
anatomical
lung
resection.Medline,
Embase
Cochrane
databases
were
searched
until
1
October
2022.
Patients
undergoing
at
least
>70%
resections
through
thoracoscopy
reporting
included.
Due
high
inter-study
variability
an
explorative
next
analytic
was
performed.
The
quality
evidence
has
been
evaluated
using
Grading
Recommendations
Assessment,
Development
Evaluation
system.A
total
51
studies
comprising
5573
patients
Mean
24,
48
72
h
with
95%
confidence
interval
on
0-10
scale
calculated.
Length
hospital
stay,
nausea
vomiting,
additional
opioids
use
rescue
analysed
as
secondary
outcomes.
A
common-effect
size
estimated
extreme
heterogeneity
for
which
pooling
not
appropriate.
An
exploratory
demonstrated
acceptable
Numeric
Rating
Scale
<4
all
techniques.This
extensive
literature
attempt
pool
demonstrates
that
is
gaining
popularity
over
thoracic
in
resection,
despite
great
limitations
current
precluding
such
recommendations.ID
number
205311.
Journal of Pain Research,
Год журнала:
2023,
Номер
Volume 16, С. 707 - 724
Опубликована: Март 1, 2023
Thoracic
epidural
analgesia
(TEA)
and
thoracic
paravertebral
blocks
(PVB)
are
well-established
techniques
for
pain
management
in
thoracotomy.
Here,
we
examine
the
efficacy
of
various
fascial
plane
vs
TEA
PVB
intraoperative
postoperative
video
assisted
thoracoscopy
surgery
(VATS)
with
network
meta-analysis.A
search
prospective
randomized
control
studies
using
adult
patients
undergoing
VATS
general
anesthesia.
The
interventions
interest
were
any
regional
anesthesia
used
after
VATS.
Primary
outcomes
24-hour
opioid
requirement
scores.
A
Bayesian
meta-analysis
was
conducted.We
identified
42
that
fulfilled
our
inclusion
criteria.
For
who
underwent
VATS,
(MD
=
-27MME,
95%
CI
-46.2
to
-9MME),
ESP
-20MME,
-33
-7.9MME),
-15MME,
-26
-4.5MME)
demonstrated
significant
sparing
efficacy,
as
well
reduction
cumulative
static
However,
exclusion
one
study
due
high
risk
bias
revealed
did
not
significantly
reduce
consumption,
nor
it
incidence
PONV,
pulmonary
complications,
or
LOS
when
compared
ESP,
SAP,
PVB,
ICN,
PECS
blocks.Our
findings
suggest
provide
superior
relief
following
Therefore,
propose
a
suitable
intervention
prevention
BMC Anesthesiology,
Год журнала:
2024,
Номер
24(1)
Опубликована: Янв. 4, 2024
Abstract
Background
Although
video-assisted
thoracoscopic
surgery
(VATS)
has
advantages
of
reduced
injury
and
faster
healing,
patients
still
endure
moderate
severe
postoperative
pain.
Paracetamol
mannitol
injection,
the
first
acetaminophen
injection
in
China,
convenient
administration,
rapid
onset
action,
no
first-pass
effect.
This
aim
this
study
was
to
investigate
efficacy
analgesia
with
paracetamol
combined
thoracic
paravertebral
nerve
block
(TPVB)
post
VATS
Methods
a
single-center,
prospective,
randomized,
double-blind
controlled
clinical
trial.
Patients
scheduled
for
were
randomly
divided
into
three
groups,
general
anesthesia
group
(Group
C),
TPVB
T)
+
TP).
In
study,
primary
outcome
determined
as
visual
analog
scale
(VAS)
scores
at
rest
coughing,
secondary
observation
outcomes
time
use
analgesic
pump,
total
consumption
oxycodone
number
effective
pump
compressions
48
h
postoperatively,
perioperative
sufentanil,
extubation,
hospital
length
stay,
urine
volume,
incidence
adverse
events.
Results
state
cough,
Group
TP
showed
significantly
lower
VAS
pain
1,
12,
24,
postoperative-hour
compared
C
T.
Intraoperative
sufentanil
consumption,
press
times
patient-
(PCA)
than
those
Interestingly,
output
higher
TP.
There
differences
between
groups
terms
extubation
time,
stay
effects,
indicating
that
intravenous
is
an
safe
method.
Conclusions
may
provide
important
beneficial
effects
on
acute
control
reduce
opioid
undergoing
VATS.
Trial
registration
The
trial
registered
Jun
19,
2023
Chinese
Clinical
Registry
(
https://www.chictr.org.cn/showproj.html?proj=199315
),
ChiCTR2300072623
(19/06/2023).
Abstract
Background
The
optimal
modality
for
postoperative
analgesia
after
uniportal
video-assisted
thoracoscopic
surgery
(UVATS)
the
treatment
of
lung
cancer
has
not
yet
been
determined.
Both
ultrasound-guided
paravertebral
block
(PVB)
and
retrolaminar
(RLB)
have
reported
to
be
successful
in
providing
UVATS.
However,
which
technique
provides
superior
UVATS
is
still
unclear.
This
randomized
study
was
designed
compare
analgesic
effects
adverse
events
associated
with
PVB
RLB
Methods
Sixty
patients
were
undergo
(group
P)
or
R).
In
group
P,
30
mL
0.5%
ropivacaine
injected
at
T3
T5
levels
via
(15
each
level
on
operative
side).
R,
primary
outcome
numerical
rating
scale
(NRS)
score
within
48
h
surgery.
secondary
outcomes
total
sufentanil
consumption,
time
first
request
events.
Results
At
3,
6,
12,
24,
36
postoperatively,
NRS
rest
P
lower
than
that
R
(
p
<
0.05).
24
while
coughing
consumption
significantly
0.001).
Additionally,
longer
0.0001).
incidence
nausea
higher
Conclusions
undergoing
UVATS,
better
results
less
RLB.
Compared
RLB,
seems
a
Trial
registration
name
this
Effect
And
Mechanism
Of
Ultrasound-guided
Multimodal
Regional
Nerve
Block
On
Acute
Chronic
Pain
After
Thoracic
Surgery.
registered
Chinese
Clinical
Registry
ChiCTR2100044060
).
date
March
9,
2021.
Videosurgery and Other Miniinvasive Techniques,
Год журнала:
2023,
Номер
unknown, С. 52 - 68
Опубликована: Янв. 23, 2023
Nerve
block
is
widely
used
for
pain
management
after
video-assisted
thoracoscopic
surgery
(VATS).
Thoracic
paravertebral
(TPVB),
erector
spinae
plane
(ESPB),
serratus
anterior
(SAPB),
and
intercostal
nerve
(ICNB)
are
alternative
treatments.Network
meta-analysis
based
on
Bayesian
analyses
was
performed
to
obtain
results
direct
comparison,
indirect
network
make
rankings
probabilities.
Covariates
were
adjusted
determine
the
effect
of
covariates
this
study.The
study
identified
61
randomized
controlled
trials
(RCTs)
(4468
patients).
There
probability
ranking
first
("best"
treatment):
24
h
morphine
consumption,
TPVB
>
ESPB
ICNB
SAPB.
Covariate
adjustment
allowed
four
treatments
change
somewhat
in
likelihood
best
choice.TPVB
ranks
our
analysis.
a
viable
alternative.
SAPB
seem
play
limited
role
postoperative
management.
Journal of Cardiothoracic Surgery,
Год журнала:
2024,
Номер
19(1)
Опубликована: Июль 1, 2024
In
this
study,
we
compared
the
analgesic
effects
of
intercostal
nerve
block
(ICNB),
ultrasound-guided
paravertebral
(PVB),
and
epidural
(EB)
following
single-port
thoracoscopic
lung
surgery.