New Treatments (MSC) in Immune Disorders Like Cancers and Covid Infection: Cancer and Virus New Treatment (MSC ) DOI Creative Commons

Nadia Ghasemi Darestani,

Soheyla Hashemi,

Zahra Rahimi

и другие.

Asian Pacific Journal of Cancer Biology, Год журнала: 2024, Номер 9(2), С. 257 - 261

Опубликована: Апрель 15, 2024

The recent coronavirus disease 2019 outbreak and viral infections around the world has had an enormous impact on global health burden, threatening lives of many individuals, spatially with underlying like cancerous patients severe socio-economic consequences. Many pharmaceutical biotechnology companies have commenced intensive research different therapeutic strategies, from repurposed antiviral drugs to vaccines monoclonal antibodies prevent spread treat infected patients. Among various advanced approaches including cell- gene-editing-based therapeutics are also being investigated, initial results in in-vitro early phase I studies been promising. However, further assessments required. This article reviews mechanisms for pathogenesis of, discusses available candidates modalities that evaluated used treatment immune deficient cancers viruses infected.

Язык: Английский

Advances in gene therapy for high-grade glioma: a review of the clinical evidence DOI
Matthew Goldman,

Alexandra M. Baskin,

Martyn A. Sharpe

и другие.

Expert Review of Neurotherapeutics, Год журнала: 2024, Номер 24(9), С. 879 - 895

Опубликована: Авг. 1, 2024

Introduction High-grade glioma (HGG) is one of the most deadly and difficult cancers to treat. Despite intense research efforts, there has not been a significant breakthrough in treatment outcomes since early 2000's. Anti-glioma gene therapy demonstrated promise preclinical studies under investigation numerous clinical trials.

Язык: Английский

Процитировано

2

Immunotherapeutic Approaches for the Treatment of Glioblastoma Multiforme: Mechanism and Clinical Applications DOI Open Access
Suprava Das, Banendu Sunder Dash,

Thejas P. Premji

и другие.

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(13), С. 10546 - 10546

Опубликована: Июнь 23, 2023

Glioma is one of the most aggressive types primary brain tumor with a high-grade glioma known as glioblastoma multiforme (GBM). Patients diagnosed GBM usually have an overall survival rate less than 18 months after conventional therapy. This bleak prognosis underlines need to consider new therapeutic interventions for treatment overcome current limitations. By highlighting different immunotherapeutic approaches currently in preclinical and clinical trials, including immune checkpoint inhibitors, chimeric antigen receptors T cells, natural killer vaccines, combination therapy, this review aims discuss mechanisms, benefits, limitations immunotherapy treating patients.

Язык: Английский

Процитировано

6

The Effects of Mesenchymal Stem Cells Loaded with Oncolytic Coxsackievirus A21 on Mouse Models of Colorectal Cancer DOI

Reza Karbalaee,

Saber Mehdizadeh, Hadi Esmaeili Gouvarchin Ghaleh

и другие.

Current Cancer Drug Targets, Год журнала: 2024, Номер 24(9), С. 967 - 974

Опубликована: Фев. 4, 2024

Cancer is a major cause of death worldwide. Colorectal cancer the second most common type. Additional treatments like chemotherapy and radiation therapy may be recommended. Developing new techniques vital due to drug resistance lack targeted therapies.

Язык: Английский

Процитировано

1

Microbial-Based Therapies in Cancer Treatment Under the One Health Initiative DOI
Charalampos Filippou,

Yiannis Panayiotou,

Sophia Themistocleous

и другие.

Interdisciplinary cancer research, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

1

New Treatments (MSC) in Immune Disorders Like Cancers and Covid Infection: Cancer and Virus New Treatment (MSC ) DOI Creative Commons

Nadia Ghasemi Darestani,

Soheyla Hashemi,

Zahra Rahimi

и другие.

Asian Pacific Journal of Cancer Biology, Год журнала: 2024, Номер 9(2), С. 257 - 261

Опубликована: Апрель 15, 2024

The recent coronavirus disease 2019 outbreak and viral infections around the world has had an enormous impact on global health burden, threatening lives of many individuals, spatially with underlying like cancerous patients severe socio-economic consequences. Many pharmaceutical biotechnology companies have commenced intensive research different therapeutic strategies, from repurposed antiviral drugs to vaccines monoclonal antibodies prevent spread treat infected patients. Among various advanced approaches including cell- gene-editing-based therapeutics are also being investigated, initial results in in-vitro early phase I studies been promising. However, further assessments required. This article reviews mechanisms for pathogenesis of, discusses available candidates modalities that evaluated used treatment immune deficient cancers viruses infected.

Язык: Английский

Процитировано

1