Revolutionizing Dentistry: Preclinical Insights and Future Applications of mRNA Vaccines in Dentistry—A Narrative Review DOI Creative Commons
Luciana Koren,

Andro Koren,

Robert Likić

и другие.

Dentistry Journal, Год журнала: 2025, Номер 13(2), С. 79 - 79

Опубликована: Фев. 13, 2025

Background: Recent advances in mRNA vaccine technology, accelerated by the global COVID-19 pandemic, have generated significant interest their applications beyond infectious diseases. Dentistry has emerged as a promising field for exploring potential of mRNA-based therapies preventing and treating oral Objectives: This narrative review aims to evaluate current status development its preclinical health, focusing on periodontal disease, dental caries, regenerative medicine, implantology, cancer. Methods: The synthesizes findings from studies, including research conducted animal models vitro, assess modulate immune responses promote tissue regeneration cavity. Clinical trials were only mentioned context broader areas implementation such oncology immunotherapy. Results: studies highlight capacity vaccines enhance body's response facilitate repair processes. Despite these results, challenges persist delivering effectively within complex environment. These include stability, delivery mechanisms, modulation responses. Conclusions: While offer promise revolutionizing health care, they face notable limitations concerning safety, efficacy, clinical feasibility. Overcoming obstacles through further is essential unlock full translational ensure safe effective integration into practice.

Язык: Английский

Revolutionizing Dentistry: Preclinical Insights and Future Applications of mRNA Vaccines in Dentistry—A Narrative Review DOI Creative Commons
Luciana Koren,

Andro Koren,

Robert Likić

и другие.

Dentistry Journal, Год журнала: 2025, Номер 13(2), С. 79 - 79

Опубликована: Фев. 13, 2025

Background: Recent advances in mRNA vaccine technology, accelerated by the global COVID-19 pandemic, have generated significant interest their applications beyond infectious diseases. Dentistry has emerged as a promising field for exploring potential of mRNA-based therapies preventing and treating oral Objectives: This narrative review aims to evaluate current status development its preclinical health, focusing on periodontal disease, dental caries, regenerative medicine, implantology, cancer. Methods: The synthesizes findings from studies, including research conducted animal models vitro, assess modulate immune responses promote tissue regeneration cavity. Clinical trials were only mentioned context broader areas implementation such oncology immunotherapy. Results: studies highlight capacity vaccines enhance body's response facilitate repair processes. Despite these results, challenges persist delivering effectively within complex environment. These include stability, delivery mechanisms, modulation responses. Conclusions: While offer promise revolutionizing health care, they face notable limitations concerning safety, efficacy, clinical feasibility. Overcoming obstacles through further is essential unlock full translational ensure safe effective integration into practice.

Язык: Английский

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