Prevalence and genotype distribution of human papillomavirus in individuals referred to a laboratory in Urmia, Iran DOI Creative Commons

Saber Mojarrad,

Mojtaba Najmafshar,

Zahra Kargar Jahromi

и другие.

Infectious Agents and Cancer, Год журнала: 2025, Номер 20(1)

Опубликована: Март 3, 2025

Human papillomavirus (HPV) is a major contributor to sexually transmitted infections, especially common in active populations. Although the majority of HPV infections resolve naturally, certain cases can develop into different types cancer. This study focused on evaluating prevalence and distribution genotypes across males females age groups who visited laboratory Urmia, Iran. Samples from genital area were obtained participants study. DNA extraction was performed using Favorgen kit (Favorgen, Taiwan), followed by genotyping through Real-Time PCR. Genotypes determined MehrViru (MehrViru, Iran). Additionally, demographic details, including age, analyzed conjunction with statistical virological data. Between 2022 2023, total 447 individuals, both referred routine visitors, attended laboratory, comprising 431 16 males. Of these, 195 tested positive for HPV, resulting an overall rate 43.6%. Among cases, 90 individuals (46.2%) infected single genotype, while 105 (53.8%) had multiple genotype infections. The most identified HPV-6 (41.0%), HPV-16 (15.4%), HPV-56 (10.8%), HPV-90 (10.8%). least HPV-43, which detected 5 (2.6%). our analysis revealed that women under 30 predominantly LR pattern also seen four men same group, all whom genotype. Our findings underscore significant presence among visiting particularly years old. identification as prevalent highlights importance age-specific intervention strategies. vaccination programs cover HPV-16, not included, underscores need comprehensive screening preventive measures address potential long-term impacts HPV-related diseases.

Язык: Английский

Prevalence and genotype distribution of human papillomavirus in individuals referred to a laboratory in Urmia, Iran DOI Creative Commons

Saber Mojarrad,

Mojtaba Najmafshar,

Zahra Kargar Jahromi

и другие.

Infectious Agents and Cancer, Год журнала: 2025, Номер 20(1)

Опубликована: Март 3, 2025

Human papillomavirus (HPV) is a major contributor to sexually transmitted infections, especially common in active populations. Although the majority of HPV infections resolve naturally, certain cases can develop into different types cancer. This study focused on evaluating prevalence and distribution genotypes across males females age groups who visited laboratory Urmia, Iran. Samples from genital area were obtained participants study. DNA extraction was performed using Favorgen kit (Favorgen, Taiwan), followed by genotyping through Real-Time PCR. Genotypes determined MehrViru (MehrViru, Iran). Additionally, demographic details, including age, analyzed conjunction with statistical virological data. Between 2022 2023, total 447 individuals, both referred routine visitors, attended laboratory, comprising 431 16 males. Of these, 195 tested positive for HPV, resulting an overall rate 43.6%. Among cases, 90 individuals (46.2%) infected single genotype, while 105 (53.8%) had multiple genotype infections. The most identified HPV-6 (41.0%), HPV-16 (15.4%), HPV-56 (10.8%), HPV-90 (10.8%). least HPV-43, which detected 5 (2.6%). our analysis revealed that women under 30 predominantly LR pattern also seen four men same group, all whom genotype. Our findings underscore significant presence among visiting particularly years old. identification as prevalent highlights importance age-specific intervention strategies. vaccination programs cover HPV-16, not included, underscores need comprehensive screening preventive measures address potential long-term impacts HPV-related diseases.

Язык: Английский

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