Linear relation association between TyG-BMI and BPH: a national prospective cohort study DOI Creative Commons
Bing Li, Zhiqiang Zhang, Chao Sun

и другие.

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Авг. 28, 2024

Abstract Objective This study aims to explore the relationship between Triglyceride Glucose Body Mass Index (TyG-BMI) and risk of developing benign prostatic hyperplasia (BPH). Methods Utilizing data from China Health Retirement Longitudinal Study (CHARLS), we included 3,301 men aged 45 above. We analyzed association TyG-BMI BPH using multivariate logistic regression restricted cubic spline models. Results During 4-year follow-up period, 268 cases were identified. There was a positive correlation (OR = 1.22, 95% CI: 1.08–1.38, p < 0.001), with significant dose-response (P 0.001). Stratified analyses indicated that impact on consistent across various subgroups. Conclusion is linear BPH. Managing levels may help reduce

Язык: Английский

Association of insulin resistance surrogates with live birth outcomes in women with polycystic ovary syndrome undergoing in vitro fertilization DOI Creative Commons
Shenghao Wu, Yanhong Wu,

Lizi Fang

и другие.

BMC Pregnancy and Childbirth, Год журнала: 2025, Номер 25(1)

Опубликована: Янв. 11, 2025

Insulin resistance (IR) is a common pathophysiologic feature in patients with polycystic ovary syndrome (PCOS). However, there have been no studies investigating the association of IR surrogates pregnancy outcomes women PCOS undergoing vitro fertilization (IVF). Therefore, we explored between these factors among patients. We conducted retrospective study that included who underwent IVF at university-affiliated hospital. Blood samples and physical examinations are collected reproductive center on fasting morning 2nd to 4th day menstrual cycle prior medication. categorized participants into "Non-IR group" (HOMA-IR < 2.2) "IR ≥ 2.2). The [triglyceride-glucose-body mass index (TyG-BMI), triglyceride-glucose (TyG) homeostasis model assessment (HOMA-IR)] was evaluated by regression analysis. Moreover, also performed sensitivity analyses stratification interaction tests. primary outcome variable live birth rate. A total 543 were finally study. In all three models for fresh embryo transfer (ET) cycles, showed stable negative correlations rate (in Model III: TyG-BMI OR = 0.99, 95% CI: 0.98 ~ 0.99; TyG 0.47, 0.27 0.82; HOMA-IR 0.84, 0.72 0.97; P 0.05), this across subgroups population (all P-interaction > 0.05). relationship did not exist frozen-thawed (FET) cycles. Furthermore, our found superior predicting ET cycles [TyG-BMI: 0.64 (95% 0.58, 0.69) vs. TyG: 0.61 0.55, 0.67) HOMA-IR: 0.60 0.67)]. Our revealed (TyG-BMI, HOMA-IR) negatively associated rates FET

Язык: Английский

Процитировано

0
Linear relation association between TyG-BMI and BPH: a national prospective cohort study DOI Creative Commons
Bing Li, Zhiqiang Zhang, Chao Sun

и другие.

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Авг. 28, 2024

Abstract Objective This study aims to explore the relationship between Triglyceride Glucose Body Mass Index (TyG-BMI) and risk of developing benign prostatic hyperplasia (BPH). Methods Utilizing data from China Health Retirement Longitudinal Study (CHARLS), we included 3,301 men aged 45 above. We analyzed association TyG-BMI BPH using multivariate logistic regression restricted cubic spline models. Results During 4-year follow-up period, 268 cases were identified. There was a positive correlation (OR = 1.22, 95% CI: 1.08–1.38, p < 0.001), with significant dose-response (P 0.001). Stratified analyses indicated that impact on consistent across various subgroups. Conclusion is linear BPH. Managing levels may help reduce

Язык: Английский

Процитировано

0