Comprehensive Review of COVID-19: Epidemiology, Pathogenesis, Advancement in Diagnostic and Detection Techniques, and Post-Pandemic Treatment Strategies

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(15), С. 8155 - 8155

Опубликована: Июль 26, 2024

At present, COVID-19 remains a public health concern due to the ongoing evolution of SARS-CoV-2 and its prevalence in particular countries. This paper provides an updated overview epidemiology pathogenesis COVID-19, with focus on emergence variants phenomenon known as ‘long COVID’. Meanwhile, diagnostic detection advances will be mentioned. Though many inventions have been made combat pandemic, some outstanding ones include multiplex RT-PCR, which can used for accurate diagnosis infection. ELISA-based antigen tests also appear potential tools available future. discusses current treatments, vaccination strategies, well emerging cell-based therapies The underscores necessity us continuously update scientific understanding treatments it.

Язык: Английский

Transcranial Direct Current Stimulation for Global Cognition in Mild Cognitive Impairment

Chonnam Medical Journal, Год журнала: 2025, Номер 61(1), С. 1 - 1

Опубликована: Янв. 1, 2025

Mild cognitive impairment (MCI) is a condition characterized by noticeable deficits in memory retrieval or other domains than the individuals with same age but do not significantly interfere daily functioning. It represents an intermediate stage between normal aging and dementia, crucial opportunity for intervention prior to extensive decline. Transcranial direct current stimulation (tDCS), non-invasive neuromodulation technique, has shown promise enhancing global cognition MCI. Current evidence suggests that tDCS provides short-term benefits, particularly attention, moderate effects observed processing speed. However, its impact on executive function language remains inconsistent, highlighting variability individual responses study methodologies. While long-term efficacy uncertain due limited longitudinal research short follow-up periods, safety concerns, especially self-administered such as home-based tDCS, underscore need proper training device innovation. Despite this, promising, portable tool enhancement MCI, potential delay progression dementia. Addressing challenges optimizing protocols, accounting neuroanatomical variability, establishing effectiveness will be essential broader clinical adoption. Future should focus standardizing methodologies, incorporating biomarkers predict treatment response, conducting large-scale, studies refine therapeutic application.

Язык: Английский

Neuropsychology practice guidance for the neuropsychiatric aspects of Long COVID

The Clinical Neuropsychologist, Год журнала: 2024, Номер unknown, С. 1 - 29

Опубликована: Авг. 23, 2024

The coronavirus disease-2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has had a profound global impact on individual health and well-being in adults children. While most fully recover from COVID-19, relatively large subgroup continues to experience persistent physical, cognitive, emotional/behavioral symptoms beyond the initial infection period. World Health Organization termed this phenomenon "Post-COVID-19 Condition" (PCC), better known as "Long COVID." Due cognitive psychosocial symptoms, neuropsychologists often assess recommend treatment for individuals with Long COVID. However, guidance neuropsychologists' involvement clinical care, policy-making, research not yet been developed. authors of manuscript convened address critical gap develop working patients presenting

Язык: Английский