Lived Experience of Diabetes Self-Management Among the Elderly in India
IntechOpen eBooks,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 23, 2025
The
World
Health
Organization
(WHO)
and
the
United
Nations
(UN)
designated
2021–2030
as
“Decade
of
Healthy
Ageing,”
which
underscores
increasing
importance
addressing
needs
an
aging
global
population.
As
emphasized
in
Longitudinal
Aging
Study
India
(LASI)
Wave
1
Report,
2020,
India,
is
frequently
referred
to
“Diabetes
Capital
World,”
grappling
with
a
substantial
burden
diabetes
among
older
adults.
Against
this
demographic
backdrop,
chapter
explores
way
elderly
Indians
handle
intricacies
self-management,
encompasses
dietary
modifications,
medication
adherence,
physical
activity,
routine
monitoring,
supported
by
family,
healthcare
providers,
community
resources.
This
endeavors
inform
professionals,
researchers,
policymakers
regarding
unique
requirements
diabetic
patients
providing
reader
personal
insights
lived
experiences,
thereby
facilitating
more
personalized
approach
care.
Язык: Английский
Kidney Failure due to Diabetic Kidney Disease Among Australians Aged ≤ 45 Years, 2000–2022: A Population‐Based Geospatial Analysis
Nephrology,
Год журнала:
2025,
Номер
30(3)
Опубликована: Март 1, 2025
ABSTRACT
Aim
Evaluate
the
area‐level
incidence
of
kidney
failure
due
to
diabetes
among
Australians
aged
≤
45
years.
Methods
Using
Australian
registry
and
census
data
(2000–2022),
rates
prevalence
(defined
as
commencing
replacement
therapy)
people
years
were
compared
by
geographical
region.
Results
Incidence
(per
100
000/year,
95%
confidence
interval)
in
Australia
was
0.72
(0.68–0.77)
2000–2011,
1.13
(1.07–1.18)
2012–2022
(incidence
rate
ratio
[IRR]
1.56,
1.50–1.62).
Between
2012
2022,
there
48
regions
where
crude
more
than
double
national
average,
highest
being
49.8
cases
per
000
year.
all
jurisdictions
had
similar
age‐sex‐adjusted
point
estimates
for
(range
0.78–1.48)
except
Northern
Territory
(15.8,
13.9–17.8).
The
most
significant
characteristics
associated
with
incident
residence
remote
areas
(IRR
13.9,
13.1–14.8,
ref.
major
cities),
socioeconomic
disadvantage
2.96,
2.75–3.19,
advantaged
areas),
Aboriginal
Torres
Strait
Islander
ethnicity
24.2,
23.0–25.5).
eras,
born
outside
largest
increase
2.47,
2.23–2.72)
but
a
lower
overall
those
0.55,
0.52–0.59).
Conclusion
In
Australia,
an
last
two
decades.
There
strong
relationship
between
risk
social
determinants
health,
including
place
residence,
status
Indigenous
status.
Язык: Английский
A review on computational tools for antidiabetic herbs research
Discover Chemistry.,
Год журнала:
2025,
Номер
2(1)
Опубликована: Апрель 15, 2025
Язык: Английский
Linking MDA Levels and Blood Glucose in Streptozotocin-Induced Rat Diabetes: Implications for Diabetic Complications and Therapeutic Strategies
Jurnal Penelitian Pendidikan IPA,
Год журнала:
2024,
Номер
10(6), С. 2898 - 2905
Опубликована: Июнь 20, 2024
Diabetes
mellitus
is
a
chronic
metabolic
disorder
characterized
by
elevated
blood
glucose
levels
resulting
from
insulin
deficiency
or
resistance.
Streptozotocin,
potent
diabetogenic
agent,
commonly
employed
to
induce
experimental
diabetes
selectively
damaging
pancreatic
beta
cells,
in
and
hyperglycemia.
Elevated
Malondialdehyde
(MDA)
levels,
indicative
of
oxidative
stress
lipid
peroxidation,
are
closely
linked
diabetic
complications.
This
study
aimed
investigate
the
association
between
MDA
Streptozotocin-induced
rat
diabetes,
shedding
light
on
potential
therapeutic
strategies.
Spectrophotometric
analysis
was
utilized
quantify
tissues,
providing
insights
into
extent
damage.
The
results
revealed
significant
correlation
glucose,
highlighting
role
pathogenesis.
These
findings
underscore
importance
targeting
management
prevent
In
conclusion,
emphasizes
relevance
monitoring
as
biomarker
for
assessing
conditions
guiding
interventions.
Язык: Английский
LncRNA LYPLAL1, miR-204-5p, and SIRT1: novel signatures for risk assessment of diabetic macrovascular complications
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Окт. 15, 2024
Long-term,
uncontrolled
diabetes
mellitus
can
lead
to
micro-
and
macrovascular
problems.
The
protective
function
of
lncRNA
LYPLAL1
is
reduce
endothelium
cell
inflammation
by
upregulating
sirtuin
1
(SIRT1)
reducing
microRNA
(miR)-204-5p.
This
work
attempted
examine
the
LYPLAL1/miR-204-5p/SIRT1
molecules
as
diagnostic
biomarkers
for
diabetic
MVC
assess
their
clinical
correlations.
study
enrolled
32
controls,
patients
with
alone,
MVC.
RT-qPCR,
or
quantitative
real-time
PCR,
was
utilized
determine
expression
levels
miR.
SIRT1
measured
ELISA.
When
comparing
cases
those
without
MVC,
values
were
significantly
lower.
Conversely,
had
higher
miR-204-5p
than
LncRNA
performed
best
in
terms
detecting
It
attained
90.6%
specificity
96.9%
sensitivity.
A
combination
three
markers
(lncRNA
LYPLAL1,
miR-204-5p,
SIRT1)
yielded
accuracy
at
98.4%.
appeared
be
an
independent
predictor.
Adjusted
OR
405
(95%
CI:
1.4-1200)
(p
=
0.039).
we
compared
Patients
demonstrated
performance
characteristics.
predictor
Язык: Английский
Evaluation of Procalcitonin in Type-2 Diabetes Mellitus Patients in Minahasa, North Sulawesi, Indonesia
International Journal of Diabetes and Endocrinology,
Год журнала:
2024,
Номер
9(4), С. 65 - 70
Опубликована: Ноя. 12, 2024
Diabetes
mellitus
(DM)
remains
a
significant
global
health
challenge,
contributing
to
high
morbidity
and
mortality
rates.
In
Indonesia,
type
2
diabetes
is
increasing,
with
substantial
percentage
of
patients
experiencing
poor
glycemic
control.
This
study
aims
explore
the
relationship
between
serum
procalcitonin
levels
fasting
blood
glucose
(FBG)
in
diabetes,
assessing
procalcitonin's
potential
as
biomarker
for
complications.
A
total
122
confirmed
were
included,
excluding
those
infection
or
recent
trauma.
Clinical
parameters,
including
pressures,
body
mass
index
(BMI),
samples
FBG
levels,
collected.
Statistical
analysis
was
performed
using
SPSS
version
26.0.
The
mean
age
participants
56.7
years,
43.4%
diagnosed
hypertension.
correlation
found
(<i>p</i>
=
0.024,
r
0.205),
indicating
weak
positive
relationship.
No
differences
observed
hypertensive
non-hypertensive
patients.
findings
suggest
that
may
serve
useful
managing
complications
associated
diabetes.
While
weak,
role
inflammation
progression
highlights
need
further
investigation.
Integrating
testing
into
clinical
practice
could
enhance
patient
management,
future
research
should
mechanisms
linking
complications,
well
establish
reference
values
diabetic
populations.
Язык: Английский
Faktor risiko yang berhubungan dengan komplikasi Diabetes Mellitus Tipe 2
Erdaliza Erdaliza,
Mitra Mitra,
Novita Rany
и другие.
Jurnal kesehatan komunitas (Journal of community health),
Год журнала:
2024,
Номер
10(3), С. 534 - 545
Опубликована: Дек. 16, 2024
Diabetes
Mellitus
Tipe
2
(DM
2)
merupakan
penyakit
kronis
dengan
prevalensi
yang
terus
meningkat
di
Indonesia
dan
global.
Komplikasi
DM
tipe
memberikan
dampak
serius
bagi
kualitas
hidup
penderita.
Adanya
peningkatan
jumlah
komplikasi
pada
pasien
RSUD
Selasih
Kabupaten
Pelalawan
menjadi
permasalahan
penelitian
ini.
Tujuan
adalah
untuk
mengidentifikasi
faktor
risiko
berhubungan
Pelalawan..
Desain
digunakan
kasus
kontrol
sampel
400
(200
200
kontrol).
Kasus
komplikasi,
sedangkan
tanpa
komplikasi.
Sampel
diambil
menggunakan
metode
systematic
random
sampling.
Data
dikumpulkan
melalui
rekam
medis
Tahun
2023.
Analisis
data
dilakukan
uji
chi-square
regresi
logistik
ganda.
Hasil
menunjukkan
bahwa
kolesterol
tinggi
(OR=206,46),
lama
menderita
(OR=79,62),
tekanan
darah
(OR=22,54),
ketidakrutinan
(OR=4,43)
secara
signifikan
2.
Intervensi
mengontrol
kolesterol,
darah,
rutin
dapat
menurunkan
Untuk
itu,
maka
perlu
adanya
edukasi
program
promosi
kesehatan
dari
Rumah
Sakit
terkait
pengelolaan
diabetes,
sehingga
mencegah
terjadinya