A Microbial Endocrinology-Designed Discovery Platform to Identify Histamine-Degrading Probiotics: Proof of Concept in Poultry DOI Creative Commons
Mark Lyte,

Karrie M. Daniels

Microorganisms, Год журнала: 2025, Номер 13(4), С. 751 - 751

Опубликована: Март 26, 2025

Histamine is a biogenic amine found across the phylogenetic spectrum, from plants to fish animals. In farm animal production, host’s production of histamine within intestinal tract serves as neurotransmitter, facilitating communication gut brain. functions additionally “bridging” chemical between immune and nervous systems it facilitates system modulation host response, thereby playing critical role in defense gut. Increased levels gut, whether originating food-borne sources or produced situ, can lead dysregulation consequent physiological harm. As such, control improve overall health broad range species. present study, we utilized Microbial Endocrinology-based approach platform technology enable discovery unique histamine-degrading bacteria microbiota. Broiler chickens were fed, not, low high histamine-supplemented diet one day age up 42 days order encourage increased abundance putative bacteria. Intestinal contents employed protocol that involved repeated isolation rounds utilizing minimal medium. We herein report genus Brevibacterium are capable 100% degradation vitro. Feeding experiments identified spp., B. sediminis isolate, demonstrated reduced amount broilers fed histamine-containing enabled an improvement growth compared non-B. sediminis-supplemented this study demonstrates usefulness for may serve potential probiotic candidates neurochemical-mediated interactions host, improving health.

Язык: Английский

Effects of a natural phytogenic feed additive on broiler performance, carcass traits, and gut health under diets with optimal and reduced energy and amino acid density DOI Creative Commons
Maged A. Al‐Garadi, Rashed A. Alhotan, Elsayed O. S. Hussein

и другие.

Poultry Science, Год журнала: 2025, Номер unknown, С. 105014 - 105014

Опубликована: Март 1, 2025

Phytogenic feed additives are gaining attention as potential alternatives to enhance broiler growth performance and efficiency. The experiment investigated the effects of supplementing diets over 35 days with two levels Fibrafid (0.15 % 0.25 %) under dietary regimes: normal amino acid density metabolizable energy (ME) (referred positive control diet plus Fibrafid: PC1+0.15 or PC1+0.25 Fibrafid) a 5 reduction in 1.5 ME negative NC1+0.15 NC1+0.25 on parameters carcass attributes Ross 308 broilers. These were compared standard (PC1 PC2, without TURBO Grow) (NC1 NC2, Grow). Performance indicators estimated during 0-9, 11-23, 24-35, 0-35. On day 35, characteristics jejunal histopathology evaluated. Results demonstrated significant improvements body weight gain conversion ratio (FCR) inclusion, particularly at trail. supplementation compensated for reduced protein, leading improved performance, gizzard Bursa weights diets. Compared NC1, show improvement villus morphology, an increase width, height, surface area, goblet cell by 5.3 %, 4.8 12.5 56.7 respectively. In conclusion, positively impacts intestinal structure, potentially improving nutrient absorption, integrity broilers, proving Fibrafid's promise viable option modern poultry nutrition.

Язык: Английский

Процитировано

0

A Microbial Endocrinology-Designed Discovery Platform to Identify Histamine-Degrading Probiotics: Proof of Concept in Poultry DOI Creative Commons
Mark Lyte,

Karrie M. Daniels

Microorganisms, Год журнала: 2025, Номер 13(4), С. 751 - 751

Опубликована: Март 26, 2025

Histamine is a biogenic amine found across the phylogenetic spectrum, from plants to fish animals. In farm animal production, host’s production of histamine within intestinal tract serves as neurotransmitter, facilitating communication gut brain. functions additionally “bridging” chemical between immune and nervous systems it facilitates system modulation host response, thereby playing critical role in defense gut. Increased levels gut, whether originating food-borne sources or produced situ, can lead dysregulation consequent physiological harm. As such, control improve overall health broad range species. present study, we utilized Microbial Endocrinology-based approach platform technology enable discovery unique histamine-degrading bacteria microbiota. Broiler chickens were fed, not, low high histamine-supplemented diet one day age up 42 days order encourage increased abundance putative bacteria. Intestinal contents employed protocol that involved repeated isolation rounds utilizing minimal medium. We herein report genus Brevibacterium are capable 100% degradation vitro. Feeding experiments identified spp., B. sediminis isolate, demonstrated reduced amount broilers fed histamine-containing enabled an improvement growth compared non-B. sediminis-supplemented this study demonstrates usefulness for may serve potential probiotic candidates neurochemical-mediated interactions host, improving health.

Язык: Английский

Процитировано

0