Опубликована: Янв. 1, 2023
International scientific conference The concept of modern pharmacy and medicine in Ukraine EU countries : proceedings (September 6–7, 2023. Wloclawek, the Republic Poland). Riga, Latvia Baltija Publishing, 80 pages.
Язык: Английский
Frontiers in Rehabilitation Sciences, Год журнала: 2023, Номер 3
Опубликована: Янв. 23, 2023
Background COVID-19 is associated with various symptoms and psychological involvement in the long term. In view of multifactorial triggering maintenance post-COVID syndrome, a multimodal therapy somatomedical psychotherapeutic content expedient. This paper compares stress patients their course rehabilitation to psychosomatic psychocardiological patients. Method Observational study control-groups clinical, standardized examination: testing (BDI-II, HELATH-49), 6-MWT as somatic parameter, two measurement points (admission, discharge). Sample characteristics, including work related parameters, general symptom-load during are evaluated. Results At admission all measures were significantly affected, but less pronounced than or (BDI-II = 19.29 ± 9.03, BDI-II 28.93 12.66, psychocardiology 24.47 10.02). During rehabilitation, complaint domains sub-groups, symptom severity was reduced (effect sizes ranging from d .34 1.22). Medium positive effects seen on self-efficacy ( .69) large activity participation 1.06) 6-MWT, walking distance improved by an average 76.43 63.58 meters Not single patient deteriorated distance, which would have been possible sign post exercise malaise (PEM). Conclusion Post-COVID slighter burden Although not curative, benefit interventions there no signs PEM.
Язык: Английский
Процитировано
37
Psychological Medicine, Год журнала: 2023, Номер 54(6), С. 1122 - 1132
Опубликована: Окт. 16, 2023
Abstract Background The post-COVID-19 condition describes the persistence or onset of somatic symptoms (e.g. fatigue) after acute COVID-19. Based on an existing cognitive-behavioral treatment protocol, we developed a specialized group intervention for individuals with condition. present study examines feasibility, acceptance, and effectiveness program inpatients in neurological rehabilitation setting. Methods comprises eight sessions includes psychoeducational experience-based interventions common psychophysiological mechanisms persistent symptoms. A feasibility trial was conducted using one-group design naturalistic N = 64 history mild COVID-19 that fulfilled WHO criteria were enrolled. After each session, evaluation forms completed psychometric questionnaires psychopathological symptom burden collected pre- post-intervention. Results well received by participants therapists. Each session rated as comprehensible overall satisfaction high. Pre-post effect sizes (of standard incl. new program; intention-to-treat) showed significantly reduced subjective fatigue ( p < 0.05, d av 0.33) improved disease coping ps 0.33–0.49). Conclusions Our results support acceptance newly Yet, findings have to be interpreted cautiously due lack control follow-up measurement, small sample size, relatively high drop-out rate.
Язык: Английский
Процитировано
23
Frontiers in Neurology, Год журнала: 2025, Номер 15
Опубликована: Янв. 6, 2025
Post COVID-19 condition (PCC) is increasingly recognized as a debilitating characterized by persistent symptoms following SARS-CoV-2 infection. Neuropsychological deficits, including cognitive impairments and fatigue, are prevalent in individuals with PCC. The PoCoRe study aimed to evaluate the burden of neuropsychological deficits PCC patients undergoing multidisciplinary indoor rehabilitation describe possible changes this symptomatology. study, prospective, non-randomized, controlled longitudinal recruited from six German centers. Eligible participants underwent comprehensive assessments at admission discharge. Various measures were employed, fatigue scale for motor functioning cognition (FSMC), Test Battery Attention (TAP) Montreal Cognitive Assessment (MoCA). Out 1,086 participants, total N = 701 included main data analysis. prevalence on was high (84.6%) decreased significantly discharge (77.4%), mild effect size. Reaction times alertness subtest abnormal 70% 50% Sustained attention 55% admission, decreasing 43% These differences significant sizes. Furthermore, 27% pathological MoCA scores 63% improved normative levels during rehabilitation, indicating treatment (p ≤ 0.001). However, demonstrated limited sensitivity detecting deficits. highlights patients, notable improvements observed rehabilitation. Challenges remain accurately identifying addressing these underscoring importance assessment tailored interventions. Further research warranted optimize screening tools enhance care both outpatient settings.
Язык: Английский
Процитировано
1
Journal of Psychosomatic Research, Год журнала: 2023, Номер 175, С. 111540 - 111540
Опубликована: Окт. 27, 2023
Язык: Английский
Процитировано
12
Infection, Год журнала: 2025, Номер unknown
Опубликована: Янв. 16, 2025
Abstract The Post COVID-19 condition (PCC) is a complex disease affecting health and everyday functioning. This well reflected by patient’s inability to work (ITW). In this study, we aimed investigate factors associated with ITW (1) design machine learning-based model for predicting (2) twelve months after baseline. We selected patients from the post COVID care study (PCC-study) data on their ability work. To identify ITW, compared PCC without ITW. For constructing predictive model, nine clinical parameters: hospitalization during acute SARS-CoV-2 infection, WHO severity of presence somatic comorbidities, psychiatric age, height, weight, Karnofsky index, symptoms. was trained predict baseline using TensorFlow Decision Forests. Its performance investigated cross-validation an independent testing dataset. total, 259 were included in analysis. observed that dyslipidemia, worse patient reported outcomes (FSS, WHOQOL-BREF, PHQ-9), higher rate preexisting conditions, more extensive medical work-up. exhibited mean AUC 0.83 (95% CI: 0.78; 0.88) 10-fold cross-validation. dataset, 0.76 0.58; 0.93). conclusion, identified several performed very well. It could guide management decisions help setting mid- long-term treatment goals aiding identification at risk extended
Язык: Английский
Процитировано
0
B&G Bewegungstherapie und Gesundheitssport, Год журнала: 2025, Номер 41(01), С. 40 - 47
Опубликована: Фев. 1, 2025
Процитировано
0
PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie, Год журнала: 2025, Номер unknown
Опубликована: Фев. 27, 2025
Zusammenfassung Nach einer SARS-CoV-2-Infektion entwickeln ca. 10% der Patient*innen eine Post-COVID-Symptomatik, Fatigue ist eines häufigsten Symptome. Diese führt zu erheblichen Einschränkung Lebens-qualität und einem hohen Arbeitsausfall. Bei Chronifizierung von Schmerzen sind dysfunktionale Muster im Sinne des Avoidance/Endurance Konzepts relevant die klinische Erfahrung mit PCS-Patienten zeigt, dass diese auch hier Rolle spielen könnten. Die explorative Beobachtungsstudie überprüft Annahme, maladaptive Angst-Vermeidungsreaktionen oder Durchhaltereaktionen bei Aufrechterhaltung Post-COVID-Fatigue-Symptomen einen signifikanten Einfluß haben. N=97 Post-COVID-Fatiguesymptomatik aus Rehabilitationseinrichtung wurden den Selbstbeurteilungsfragebögen (FSMC), Avoidance-Endurance-Verhalten (AEQ) sowie psychologische arbeitsbezogene Variablen erfasst, zusätzlich wurde ein 6-Minuten Gehtest durchgeführt. Es ergab sich folgendes Verteilungsmuster: 2/3 distress Durchhalten, 1/3 Vermeiden keine adäquaten Coper. Das Ängstlich-Vermeidende-Reaktionsmuster konnte signifikant Varianz in Fatigueausprägung aufklären (F (3, 88)=17,072, p<0,001; R²=0,368). Vermeidung körperlicher Aktivität steht erhöhten Anzahl an AU-Tagen Verbindung. Ergebnisse unterstützen Reaktionsmuster Beitrag zur Post-COVID-Symptomatik leisten, dies sollte allerdings prospektiven Studie werden. Dies spricht angesichts dieser chronifizierten Stichprobe für Bedeutung Konstrukte. Durch Screenings könnte man Vorfeld herausfiltern gezieltere, individuell abgestimmte Therapien durchführen.
Процитировано
0
Bulletin of Rehabilitation Medicine, Год журнала: 2025, Номер 24(1), С. 103 - 111
Опубликована: Фев. 25, 2025
INTRODUCTION. The new coronavirus infection COVID-19 has had a significant impact on the health of populations around world, causing not only respiratory symptoms, but also wide range systemic disorders, including autonomic dysfunction. nervous system plays key role in regulating vital body functions such as heart rate, blood pressure, respiration and metabolism. Disorders can lead to serious consequences, chronic fatigue, orthostatic hypotension, tachycardia other symptoms that markedly impair quality life patients. AIM. To analyze available scientific data dysfunction long COVID patients, its possible pathophysiological mechanisms development potential methods correction. MATERIALS AND METHODS. We have searched for full-text publications Russian English over past four years eLIBRARY.RU, PubMed, Web Science databases using keywords: dysfunction, SARS-CoV-2, insufficiency, COVID-19, COVID. RESULTS DISCUSSION. review examines detail clinical manifestations approaches correction are considered. date, many been identified CONCLUSION. analyzed studies indicate presence causal relationship between However, it is necessary further study pathophysiology characteristics spectrum associated with infection, understand natural course, optimize treatment rehabilitation measures based personalized approach.
Язык: Английский
Процитировано
0
Die Rehabilitation, Год журнала: 2025, Номер unknown
Опубликована: Апрель 15, 2025
Zusammenfassung Die häufigsten Symptome des PCS sind anhaltende Fatigue und kognitive Störungen, welche Aktivität Teilhabe im Beruf täglichen Leben erheblich beeinträchtigen. Es gibt zunehmend Evidenz für die Effektivität rehabilitativer Behandlungsansätze. Nichtsdestotrotz werden v. a. in den sozialen Medien Stimmen laut, Rehabilitation beim negativ bewerten über teilweise gravierende subjektive Verschlechterungen berichten. Ziel dieser Studie ist es, subjektiven Behandlungserfolg Zufriedenheit stationärer PCS-Patienten mit der zu objektivieren. Im Rahmen einer prospektiven Multicenter-Kohortenstudie (N=1028) wurden Patientenzufriedenheit (ZUF-8) am Ende PCS-Rehabilitation untersucht (PCS-Reha-Indikationen: Duale Reha, Psychosomatik, Neurologie Pneumologie). Häufigkeitsanalysen, Mittelwertvergleichen, Korrelationsanalysen Regressionsmodelle kamen zum Einsatz. Der wird alle PCS-Reha Indikationen hinweg als gut bis sehr eingeschätzt. Ca. 62% erleben eine Besserung körperlichen Beschwerden, ca. 58% psychischen Wohlbefindens. Allgemeinzustand Leistungsfähigkeit besserten sich bei 47% Patienten. Werden Kategorien Behandlungserfolges Zusammenschau betrachtet, so 87.5% mindestens ein Bereich. Behandlungsqualität wurde 90% ausgezeichnet bewertet. Etwa würden weiterempfehlen bzw. wiederkommen. globale korreliert r=–0,727 (p<0,001) subjektiv erlebten Entlastung, nicht aber dem 6-Minuten-Gehtest (6MWT) somatischem Surrogatparameter. Regressionsanalysen zeigten, dass lediglich Verbesserung Depressivität signifikant Einfluss auf hat, Gehstrecke oder sozialmedizinische Beurteilung (Leistungsvermögen allgemeiner Arbeitsmarkt). PCS- Rehabilitanden waren untersuchten Therapieprogramm zufrieden einen Behandlungserfolg. Von ganz überwiegenden Mehrzahl PCS-Rehabilitanden multimodale hilfreich empfunden.
Процитировано
0
Trials, Год журнала: 2025, Номер 26(1)
Опубликована: Апрель 25, 2025
Abstract Background A high number of individuals report suffering from physical and psychological sequelae symptoms after COVID-19—the so-called post COVID-19 condition. Commonly reported complaints include such as fatigue, headache, attention concentration deficits or dyspnea anxiety, post-traumatic stress, depression. Evidence-based treatment recommendations are still lacking up to this point. Associations between in chronic diseases known for a long time. Support coping with the disease improvement self-efficacy can have positive effect on course diseases. For reason, we designed randomized, controlled explorative intervention trial bodily distress disorder recovered persons. Methods Patients condition meeting criteria WHO, along disorder, randomized an control arm (TAU). Randomization takes place diagnostic interview, screening, informed consent. In total, 60 patients will be included (30 per group). The group receives cognitive behavioral therapy video-conference-based (6 weeks) mobile, respiratory biofeedback (for 4 weeks). At several time points, both groups assessed terms health status, expectation, satisfaction intervention. Furthermore, they get examination appointments. primary outcome is change self-efficacy; secondary outcomes parameters mental health, somatic symptoms, Data analyzed primarily using R SPSS. Discussion controlled, POSITIV one very first interventions burden due their different symptoms. aim study generate new evidence help cope thus, increase quality life reduce symptomatology. We expect probability that patients’ status improve result Trial registration German Clinical Register (DRKS); DRKS-ID: DRKS00030565. Registered December 22, 2022.
Язык: Английский
Процитировано
0