A multilayered regulatory network mediated by protein phosphatase 4 controls carbon catabolite repression and de-repression in Magnaporthe oryzae
Communications Biology,
Год журнала:
2025,
Номер
8(1)
Опубликована: Янв. 28, 2025
Carbon
catabolite
repression
(CCR)
and
de-repression
(CCDR)
are
critical
for
fungal
development
pathogenicity,
yet
the
underlying
regulatory
mechanisms
remain
poorly
understood
in
pathogenic
fungi.
Here,
we
identify
a
serine/threonine
protein
phosphatase
catalytic
subunit,
Pp4c,
as
essential
growth,
conidiation,
virulence,
utilization
of
carbohydrates
lipids
Magnaporthe
oryzae.
We
demonstrate
that
4
complex
(Pp4c
Smek1
subunits),
AMP-activated
kinase
(AMPK)
Snf1,
transcriptional
regulators
CreA
(repressor)
Crf1
(activator)
collaboratively
regulate
non-preferred
carbon
sources.
Protein
interaction
phosphorylation
analyses
reveal
under
glucose-rich
conditions,
Snf1
directly
status
Crf1.
In
contrast,
l-arabinose-rich
indirectly
modulates
dephosphorylation
these
transcription
factors
via
Pp4c
Smek1.
Phosphorylation-mediated
activation
or
inactivation
drives
CCR
CCDR,
thereby
governing
metabolism
sources
derived
from
plant
cell
walls
contributing
to
pathogenicity.
These
findings
provide
deep
insights
into
regulation
emphasizing
their
significance
pathogenicity
phytopathogenic
The
complex,
kinase,
control
rice
blast
fungus
Язык: Английский
A lightweight model for early perception of rice diseases driven by photothermal information fusion
Computers and Electronics in Agriculture,
Год журнала:
2025,
Номер
233, С. 110150 - 110150
Опубликована: Фев. 24, 2025
Язык: Английский
The link between changing in host carbon allocation and resistance to Magnaporthe oryzae : a possible tactic for mitigating the rice blast fungus
Plant Signaling & Behavior,
Год журнала:
2024,
Номер
19(1)
Опубликована: Март 11, 2024
One
of
the
most
destructive
diseases
affecting
rice
is
blast,
which
brought
on
by
blast
fungus
Magnaporthe
oryzae.
The
preventive
measures,
however,
are
not
well
established.
To
effectively
reduce
negative
effects
blasts
crop
yields,
it
imperative
to
comprehend
dynamic
interactions
between
pathogen
resistance
and
patterns
host
carbon
allocation.
This
review
explores
relationship
variations
in
allocation
plants'
ability
withstand
damaging
M.
highlights
potential
strategies
for
altering
including
transgenic,
selective
breeding,
rotation,
nutrient
management
practices
as
a
promising
avenue
enhancing
resistance.
study
advances
our
knowledge
interaction
oryzae
provides
stakeholders
farmers
with
practical
guidance
mitigating
adverse
globally.
information
may
be
used
future
create
varieties
that
resistant
Язык: Английский
The endosomal–vacuolar transport system acts as a docking platform for the Pmk1 MAP kinase signaling pathway in Magnaporthe oryzae
New Phytologist,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 4, 2024
Summary
In
Magnaporthe
oryzae
,
the
Pmk1
MAP
kinase
signaling
pathway
regulates
appressorium
formation,
plant
penetration,
effector
secretion,
and
invasive
growth.
While
Mst11‐Mst7‐Pmk1
cascade
was
characterized
two
decades
ago,
knowledge
of
its
in
intracellular
network
remains
limited.
this
study,
we
demonstrate
that
endosomal
surface
scaffolds
MAPK
Msb2
activates
Ras2
on
endosomes
M.
.
Protein
colocalization
demonstrated
Msb2,
Ras2,
Cap1,
Mst50,
Mst11,
Mst7,
attach
to
late
membranes.
Damage
endosome–vacuole
transport
system
influences
phosphorylation.
When
senses
a
signal,
it
internalizes
endosome
membrane
surfaces,
transmitting
signal
via
Mst11
Mst7.
Signal‐sensing
delivery
proteins
are
ubiquitinated
sorted
for
degradation
vacuoles,
terminating
signaling.
Plant
penetration
lowered
turgor
required
transition
from
vacuoles
appressoria.
Our
findings
uncover
an
effective
mechanism
controls
through
endosomal–vacuolar
transport,
offering
new
cytological
molecular
mechanisms
by
which
modulates
development
pathogenicity
Язык: Английский