Associations between socioeconomic inequalities and progression to psychological and cognitive multimorbidities after onset of a physical condition: a multicohort study

EClinicalMedicine, Год журнала: 2024, Номер 74, С. 102739 - 102739

Опубликована: Июль 25, 2024

Язык: Английский

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Optimal dose and pattern of physical activity to prevent diagnosed depression: prospective cohort study

Psychological Medicine, Год журнала: 2025, Номер 55

Опубликована: Янв. 1, 2025

Abstract Background Little is known about the dose and pattern of moderate-to-vigorous physical activity (MVPA) to prevent depression. We aimed assess prospective association accelerometer-derived MVPA with risk diagnosed Methods included 74,715 adults aged 40–69 years from UK Biobank cohort who were free severe disease at baseline participated in accelerometer measurements (mean age 55.2 [SD 7.8]; 58% women). was derived through 1-week wrist-worn accelerometry. Diagnosed depression defined by hospitalization ICD-10 codes F32.0-F32.A. Restricted cubic splines Cox regression determined incident Results Over a median 7.9-year follow-up, there 3,089 (4.1%) cases Higher doses curvilinearly associated lower risk, largest minute-per-minute added benefits occurring between 5 (HR 0.99 [95% CI 0.96–0.99]) 280 0.67 0.60–0.74]) minutes per week (reference: 0 minutes). Conclusion Regardless pattern, higher curvilinear manner, greatest incremental benefit minute during first 4–5 h week. Optimal occurred around 15 h/week.

Язык: Английский

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Individual and Joint Associations of Cancer Diagnosis and Handgrip Strength with Depression in European Middle-Aged and Older Adults

Cancers, Год журнала: 2025, Номер 17(5), С. 754 - 754

Опубликована: Фев. 23, 2025

Background/Objectives: Depression is influenced by a multitude of interconnected factors, including cancer and handgrip strength. The purpose our study to examine how strength diagnosis are individually jointly associated with depression. Methods: An observational was employed using secondary data from the Survey Health, Aging, Retirement in Europe waves 7 8. sample comprised 641 participants (71.1 ± 7.7 years), 12 European countries. Results: Having greater odds depression (depression 2017 model: OR = 1.35, 95% CI 1.03, 1.75; 2019 1.48, 1.12, 1.95). Being higher tertile lower 2, 0.65, 0.56, 0.74 3, 0.49, 0.65; 0.74, 0.64, 0.86 0.76, 0.88). greatest reduction for found without third 2017: 0.42, 0.29, 0.61; 2019: 0.40, 0.28, 0.58). Conclusions: Both were depression, first increasing its risk latter reducing it. Individuals highest have both analyses.

Язык: Английский

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The Relationship Between Grip Strength and Cognitive Impairment: Evidence From NHANES 2011–2014

Brain and Behavior, Год журнала: 2025, Номер 15(3)

Опубликована: Март 1, 2025

ABSTRACT Background Prior research has consistently shown an association between muscle strength and various metabolic diseases. However, the relationship cognitive impairment remains elusive. Methods Using data from 2011–2014 National Health Nutrition Examination Survey (NHANES), we investigated impairment. We used multivariate logistic regression, restricted cubic spline regression (RCS), threshold effects to investigate impact of on function. In addition, analyzed correlation in subgroups age, gender, race, education, smoking status, drinking hypertension, diabetes, heart disease. Results 2124 participants were ultimately included for further analysis. Multivariate trend testing, RCS analysis showed a non‐linear negative Threshold effect suggests that when reaches certain value, this undergoes significant changes. three function scoring tests, interaction was only observed racial subgroup. Conclusion This study function, which may have effect. Further longitudinal studies are needed elucidate its potential mechanisms.

Язык: Английский

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Sex-related differences in the associations between wishing to die, grip strength, and physical activity: An analysis in European middle-aged and older adults

Journal of Affective Disorders, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Язык: Английский

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Depression and sarcopenia-related traits: A Mendelian randomization study

World Journal of Psychiatry, Год журнала: 2023, Номер 13(11), С. 929 - 936

Опубликована: Ноя. 17, 2023

Observational studies have suggested that depression is associated with sarcopenia. However, the causal relationship between and sarcopenia remains unclear.To investigate sarcopenia.We performed a Mendelian randomization (MR) analysis to identify bidirectional sarcopenia-related traits. Summary-level data independent variants used as instrumental variables came from large genome-wide association of (414055 cases 892299 controls), appendicular lean mass (ALM, 450243 participants), hand grip strength (exposure: 360000 participants; outcome: 334925 participants).We identified negative lower ALM [odds ratio (OR): 0.932, 95% confidence interval (95%CI): 0.889-0.979, P = 0.005]. In reverse MR analysis, we also observed an inverse (OR: 0.200, 95%CI: 0.108-0.370, < 0.001). Similar results were obtained in sensitivity analyses.Depression was causally related decreased muscle mass, declined might lead higher risk depression.

Язык: Английский

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Association between handgrip strength and depressive symptoms in patients undergoing hemodialysis: a cross-sectional study from a single Chinese center

BMC Psychiatry, Год журнала: 2024, Номер 24(1)

Опубликована: Март 5, 2024

Abstract Background The relationship between handgrip strength (HGS) and depression in patients undergoing hemodialysis (HD) was unknown. Therefore, we aimed to clarify this association a cohort of patients. Methods HGS used as representative indicator muscle measured with handheld dynamometer. Depressive symptoms were assessed the self-reported Patient Health Questionnaire-9. A multivariable logistic regression model restricted cubic spline analysis assess depression. Results prevalence our study 34% 568 Chinese HD. Compared lowest tertiles absolute weighted HGS, highest had an approximately 59% lower [odds ratio (OR) = 0.41, 95% confidence interval (CI) 0.24–0.68; OR 95%CI (0.24–0.69)] depressive after multivariate adjustments. Besides, risk decreased by 33% (OR 0.67, 0.53–0.85) 32% 0.68, 0.54–0.85) for each standard deviation increase respectively. both increasing adjustments ( p trend < 0.05). Furthermore, linear dose-response observed nonlinearity >0.05). Conclusions This suggests that strength, simple modifiable parameter, is associated higher Considering often unrecognized or underdiagnosed HD patients, lowered should be important incentive medical staff screen

Язык: Английский

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Bidirectional Associations Between Cardiometabolic Multimorbidity and Depression and Mediation of Lifestyles

JACC Asia, Год журнала: 2024, Номер 4(9), С. 657 - 671

Опубликована: Авг. 13, 2024

Cardiometabolic multimorbidity (CMM) and depression are major health concerns, the onset of either condition may heighten risk developing other.

Язык: Английский

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Associations between muscular strength and mental health in cognitively normal older adults: a cross-sectional study from the AGUEDA trial

International Journal of Clinical and Health Psychology, Год журнала: 2024, Номер 24(2), С. 100450 - 100450

Опубликована: Март 19, 2024

To examine the associations between muscular strength and mental health. We used baseline data of 91 cognitively healthy older adults (71.69 ± 3.91 years old, 57 % women) participating in AGUEDA randomized controlled trial. Muscular was assessed using both objective (i.e., handgrip strength, biceps curl, squats, isokinetic test) perceived International Fitness Scale) indicators. Psychological ill-being indicators: anxiety, depression, stress, loneliness; psychological well-being satisfaction with life, self-esteem, emotional well-being) were a set valid reliable self-reported questionnaires. Linear regression analyses performed adjusting for sex, age, education, body mass index , alcohol, diet, smoking (model 1), additionally by cardiorespiratory fitness 2). Elbow extension positively associated stress model 1 (β = 0.252, 95 Confidence Interval [95 CI] 0.007 to 0.497, p 0.044), even after further adjustment 0.282, CI 0.032 0.532, 0.028). Perceived negatively depressive symptoms -0.271, -0.491 -0.049, 0.017) 2 reported tending towards significant -0.220, -0.445 0.005, 0.055). Handgrip self-esteem 0.558, 0.168 0.949, 0.006) 0.546, 0.135 0.956, 0.010). No found among other health variables. had moderate association there small elbow stress. observed outcomes normal adults.

Язык: Английский

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The association of depressive symptoms with handgrip strength and gait speed in community-dwelling older adults: data from the baseline phase of Birjand Longitudinal Aging Study

BMC Geriatrics, Год журнала: 2024, Номер 24(1)

Опубликована: Май 3, 2024

Abstract Background Depression is a multifaceted condition with high prevalence and burden to society. Handgrip strength (HGS) gait speed (GS) are indices of physical health, which linked mental health. Previous studies have shown heterogeneity among countries in the association parameters depression. In this study, we aimed investigate HGS GS depressive symptoms older adults. Methods This cross-sectional study analyzing data from Birjand Longitudinal Aging Study, cohort community-dwelling adults (≥ 60 years old). Depressive were assessed by nine-item Patient Health Questionnaire. was measured hand dynamometer sitting position, estimated 15-foot walk test at usual pace. Results Compared participants first quartile, those second quartile had significantly lower odds suffering symptoms, while not associated symptoms. A higher risk moderate related moderately severe Conclusions Our findings suggest that people residing Birjand, Iran less likely suffer than HGS.

Язык: Английский

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