Neurological Sciences,
Год журнала:
2020,
Номер
41(6), С. 1437 - 1449
Опубликована: Фев. 12, 2020
Abstract
Background
Many
patients
with
brain
tumours
exhibit
mild
to
severe
(neuro)cognitive
impairments
at
some
point
during
the
course
of
disease.
Social
cognition,
as
an
instance
higher-order
cognitive
functioning,
specifically
enables
initiation
and
maintenance
appropriate
social
interactions.
For
individuals
being
confronted
diagnosis
a
tumour,
impairment
function
represents
additional
burden,
since
those
deeply
depend
on
support
empathy
provided
by
family,
friends
caregivers.
Methods
The
present
study
explores
scientific
landscape
(socio)cognitive
functioning
in
tumour
conducting
comprehensive
bibliometric
analysis
using
VOSviewer.
Web
Science
Core
Collection
database
was
examined
identify
relevant
documents
published
between
1945
2019.
Results
A
total
664
English
titles
functions
retrieved.
Automated
textual
revealed
that
data
available
so
far
focus
three
major
topics
patients:
general
paediatric
cases,
well
psychological
factors
their
influence
quality
life.
research
has
gradually
moved
from
clinical
studies
one
outcome
measures
investigations
interactions
constructs
such
anxiety,
depression
or
fatigue.
Medical,
neurological
neuropsychological
journals,
particular
neuro-oncological
journals
most
articles
authored
relatively
small
network
interconnected
researchers
field.
Conclusion
highlights
necessity
more
cognition
patients.
JNCI Cancer Spectrum,
Год журнала:
2024,
Номер
8(2)
Опубликована: Фев. 29, 2024
Abstract
Purpose
Cancer
survivors
commonly
report
cognitive
declines
after
cancer
therapy.
Due
to
the
complex
etiology
of
cancer-related
decline
(CRCD),
predicting
who
will
be
at
risk
CRCD
remains
a
clinical
challenge.
We
developed
model
predict
breast
would
experience
systematic
treatment.
Methods
used
Thinking
and
Living
with
study,
large
ongoing
multisite
prospective
study
older
complete
assessments
pre-systemic
therapy,
12
months
24
initiation
systemic
Cognition
was
measured
using
neuropsychological
testing
attention,
processing
speed,
executive
function
(APE).
defined
as
0.25
SD
(of
observed
changes
from
baseline
in
matched
controls)
or
greater
APE
score
(transient)
persistent
sustained
months.
machine
learning
approaches
demographics,
tumor
characteristics
treatment,
genotypes,
comorbidity,
self-reported
physical,
psychosocial,
function.
Results
Thirty-two
percent
had
transient
decline,
41%
these
women
experienced
decline.
Prediction
good:
yielding
an
area
under
curve
0.75
0.79
for
respectively.
Variables
most
informative
included
apolipoprotein
E4
positivity,
HER2
obesity,
cardiovascular
comorbidities,
more
prescription
medications,
higher
score.
Conclusions
Our
proof-of-concept
tool
demonstrates
our
prediction
models
are
potentially
useful
CRCD.
Future
research
is
needed
validate
this
approach
routine
practice
settings.
Purpose:
Breast
cancer
survivors
often
experience
cancer-related
cognitive
impairment
(CRCI),
such
as
problems
with
memory
and
attention.
However,
typical
neuropsychological
test
batteries
are
unable
to
capture
the
day-to-day
variability
of
cognition
may
be
underestimating
CRCI.
The
present
study
aims
assess
feasibility,
usability,
validity
a
novel
ecological
momentary
assessment
(EMA)
app
cognition.Methods:
Nineteen
breast
6–36-months
post-chemotherapy
26
healthy
controls
completed
NIH
Toolbox
Cognition
Battery.
Subsequently,
participants
EMA
(once
day,
for
30
days)
comprising
four
tasks
assessing
processing
speed,
working
memory,
inhibition,
At
conclusion
app,
usability
questionnaire
on
which
content
analysis
was
performed.
Feasibility
assessed
against
eight
criteria,
including
accessibility,
compliance
technical
smoothness.
Convergent
construct
using
Spearman's
correlation
analyses
between
toolbox
app.Results:
Five
feasibility
criteria
were
met,
including:
motivation,
participation
rate,
drop-out,
data
collection.
Additionally,
our
revealed
themes
important
usability:
self-development,
altruism,
engagement,
functionality.
Majority
moderately
positively
correlated
corresponding
constructs
(R’s
range:
0.55-0.64),
indicating,
better
performance
coincided
toolbox.
Conclusions:
Our
findings
show
accessible,
motivated
complete
sessions
showed
good
validity.
can
used
comprehensive
measure
in
survivors.
Neurological Sciences,
Год журнала:
2020,
Номер
41(6), С. 1437 - 1449
Опубликована: Фев. 12, 2020
Abstract
Background
Many
patients
with
brain
tumours
exhibit
mild
to
severe
(neuro)cognitive
impairments
at
some
point
during
the
course
of
disease.
Social
cognition,
as
an
instance
higher-order
cognitive
functioning,
specifically
enables
initiation
and
maintenance
appropriate
social
interactions.
For
individuals
being
confronted
diagnosis
a
tumour,
impairment
function
represents
additional
burden,
since
those
deeply
depend
on
support
empathy
provided
by
family,
friends
caregivers.
Methods
The
present
study
explores
scientific
landscape
(socio)cognitive
functioning
in
tumour
conducting
comprehensive
bibliometric
analysis
using
VOSviewer.
Web
Science
Core
Collection
database
was
examined
identify
relevant
documents
published
between
1945
2019.
Results
A
total
664
English
titles
functions
retrieved.
Automated
textual
revealed
that
data
available
so
far
focus
three
major
topics
patients:
general
paediatric
cases,
well
psychological
factors
their
influence
quality
life.
research
has
gradually
moved
from
clinical
studies
one
outcome
measures
investigations
interactions
constructs
such
anxiety,
depression
or
fatigue.
Medical,
neurological
neuropsychological
journals,
particular
neuro-oncological
journals
most
articles
authored
relatively
small
network
interconnected
researchers
field.
Conclusion
highlights
necessity
more
cognition
patients.
