Anoctamins mediate polymodal sensory perception and larval metamorphosis in a non-vertebrate chordate

Cell Reports, Год журнала: 2025, Номер 44(5), С. 115578 - 115578

Опубликована: Апрель 16, 2025

Язык: Английский

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Mechanism of action and therapeutic value of anoctamin-1 in gastrointestinal cancers

Frontiers in Immunology, Год журнала: 2025, Номер 16

Опубликована: Май 6, 2025

Gastrointestinal (GI) cancers are main causes of poor health, with most remaining difficult to treat effectively. Identifying new targets for treatment is crucial improving the efficacy tumour therapies and enhancing patient quality life. Anoctamin-1 (ANO1), a component calcium-activated chloride channels (CaCCs), expressed widely in various cell types, including epithelial cells, vascular smooth muscle influences proliferation migration. Nonetheless, exact pathways through which ANO1 contributes malignant transformation immune responses remain elusive. This review comprehensively examines regulatory functions potential therapeutic applications GI cancers. The goal this work offer perspectives further study on role gastrointestinal support improvements strategies cancer diagnosis targeting ANO1.

Язык: Английский

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Development of cell labeling and gene editing tools in urochordate Ciona

Marine Life Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Июнь 3, 2025

Язык: Английский

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Editorial

Bioelectricity, Год журнала: 2024, Номер 6(4), С. 239 - 239

Опубликована: Ноя. 28, 2024

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