Elimination of the neuroparsin neuroendocrine cells in Drosophila virilis using the UAS-Gal4 system shows that neuroparsin is not important for reproduction in this species.
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 1, 2024
Neuroparsin
is
a
common
insect
neurohormone
produced
in
large
neuroendocrine
cells
the
brain
and
important
mosquito
reproduction.
Although
it
present
many
flies
including
Drosophila
species,
was
lost
from
D.
melanogaster
few
closely
related
species.
Three
different
lines
of
transgenic
virilis
were
produced:
One
that
expresses
yeast
transcription
factor
gal4
under
control
neuroparsin
promoter
(NP-gal4),
while
others
codes
for
proteins
promoter,
either
enhanced
green
fluorescent
protein
(UAS-eGFP)
or
ortholog
reaper,
an
apoptosis
inducing
(UAS-rpr).
Crosses
between
UAS-eGFP
NP-gal4
revealed
expression
correct.
UAS-rpr
completely
eliminated
cells,
but
without
effect
on
Язык: Английский
PLOS Biology and the life sciences in 2024
PLoS Biology,
Год журнала:
2024,
Номер
22(12), С. e3002985 - e3002985
Опубликована: Дек. 18, 2024
As
we
reach
the
end
of
2024,
celebrate
an
amazing
year
science
for
PLOS
Biology
and
life
sciences
more
broadly,
thank
everyone
who
continues
to
support
journal.
Язык: Английский