Russian Journal of General Chemistry, Год журнала: 2024, Номер 94(13), С. 3617 - 3626
Опубликована: Дек. 1, 2024
Язык: Английский
Russian Journal of General Chemistry, Год журнала: 2024, Номер 94(13), С. 3617 - 3626
Опубликована: Дек. 1, 2024
Язык: Английский
Biomass Conversion and Biorefinery, Год журнала: 2024, Номер unknown
Опубликована: Май 17, 2024
Язык: Английский
Процитировано
2Journal of Fungi, Год журнала: 2023, Номер 9(8), С. 786 - 786
Опубликована: Июль 26, 2023
Genetically engineering microorganisms to produce chemicals has changed the industrialized world. The budding yeast Saccharomyces cerevisiae is frequently used in industry due its genetic tractability and unique metabolic capabilities. S. been engineered novel compounds from diverse sugars found lignocellulosic biomass, including pentose sugars, like xylose, not recognized by organism. Engineering high flux toward proved be more challenging than anticipated since simply introducing pathway components often enough. Several studies show that rewiring of upstream signaling required direct products pathways interest, but doing so can diminish stress tolerance, which important industrial conditions. As an example these challenges, we reviewed efforts, enabling anaerobic xylose fermentation as a model system showcasing regulatory interplay’s controlling growth, metabolism, defense. Enabling requires introduction several key enzymes also three at intersection growth defense responses: RAS/PKA, Snf1, osmolarity glycerol (HOG) pathways. current here suggest modulation global should adopted into biorefinery microbial pipelines increase efficient product yields.
Язык: Английский
Процитировано
3Synthetic and Systems Biotechnology, Год журнала: 2024, Номер 10(1), С. 207 - 217
Опубликована: Окт. 30, 2024
Язык: Английский
Процитировано
0Current Opinion in Plant Biology, Год журнала: 2024, Номер 82, С. 102667 - 102667
Опубликована: Ноя. 19, 2024
Язык: Английский
Процитировано
0Russian Journal of General Chemistry, Год журнала: 2024, Номер 94(13), С. 3617 - 3626
Опубликована: Дек. 1, 2024
Язык: Английский
Процитировано
0