Estrogen-Related Receptor is Required in Adult Drosophila Females for Germline Stem Cell Maintenance

Опубликована: Янв. 1, 2025

Язык: Английский

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Insect nuclear receptors: From orphans to ligands

Elsevier eBooks, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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The Drosophila Estrogen-Related Receptor promotes triglyceride storage within the larval fat body

Journal of Lipid Research, Год журнала: 2025, Номер unknown, С. 100815 - 100815

Опубликована: Апрель 1, 2025

Язык: Английский

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Estrogen-Related Receptor Potential Target Genes in Silkworm (Bombyx mori): Insights into Metabolic Regulation

Insects, Год журнала: 2025, Номер 16(5), С. 469 - 469

Опубликована: Апрель 29, 2025

Estrogen-related receptors (ERRs) are important transcription factors within the nuclear receptor family that regulate cellular energy storage and consumption by binding to estrogen-related response elements (ERREs) on gene promoters. While ERRs' role in vertebrates is well-studied, their molecular mechanisms insect metabolism development remain unclear. This study systematically summarizes functions of ERRs insects, focusing silkworms analyzing comparing databases. ERRE-like were identified 2000 bp upstream promoter regions 69 metabolism-related silkworm genes. Furthermore, electrophoretic mobility shift assays (EMSAs) revealed ERREs promoters 15 genes related sugar, fat, protein specifically bind ERR. Notably, an ERRE trehalose transporter 1 (BmTret1), crucial for homeostasis hemolymph, exhibited significantly enhanced activity ERR-overexpressing cells. These findings suggest ERR a potential regulatory factor refine its metabolic network. highlights broader more critical insects than previously recognized, contributing deeper understanding applications fields.

Язык: Английский

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Estrogen-Related Receptor is Required in Adult Drosophila Females for Germline Stem Cell Maintenance

Developmental Biology, Год журнала: 2025, Номер unknown

Опубликована: Май 1, 2025

Язык: Английский

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TheDrosophilaEstrogen-Related Receptor promotes triglyceride storage within the larval fat body

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Сен. 15, 2024

The Estrogen-Related Receptor (ERR) family of nuclear receptors (NRs) serve key roles in coordinating triglyceride (TAG) accumulation with juvenile growth and development. In both insects mammals, ERR activity promotes TAG storage during the post-embryonic phase, loss-of-function mutations mouse

Язык: Английский

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Myosuppressin signaling deficiency affects ovarian development via repression of 20-hydroxyecdysone biosynthesis in Grapholita molesta

Pesticide Biochemistry and Physiology, Год журнала: 2024, Номер 205, С. 106116 - 106116

Опубликована: Сен. 3, 2024

Язык: Английский

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Transcriptome and Expression Analysis of Glycerol Biosynthesis-Related Genes in Glenea cantor Fabricius (Cerambycidae: Lamiinae)

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(21), С. 11834 - 11834

Опубликована: Ноя. 4, 2024

Fabricius (Cerambycidae: Lamiinae) is an important pest that damages kapok trees in Southeast Asia with a wide adaptability to temperature. Glycerol protectant and energy source for insects low-temperature environments. However, glycerol biosynthesis-related genes at the molecular level are limited

Язык: Английский

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