Comparative Analysis of Active LTR Retrotransposons in Sunflower (Helianthus annuus L.): From Extrachromosomal Circular DNA Detection to Protein Structure Prediction DOI Open Access

Mikhail Kazancev,

Pavel Merkulov, Kirill N. Tiurin

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(24), С. 13615 - 13615

Опубликована: Дек. 19, 2024

Plant genomes possess numerous transposable element (TE) insertions that have occurred during evolution. Most TEs are silenced or diverged; therefore, they lose their ability to encode proteins and transposed in the genome. Knowledge of active plant TE-encoded essential for transposition evasion cell transposon silencing mechanisms remains limited. This study investigated long terminal repeat (LTR) retrotransposons (RTEs) sunflowers (Helianthus annuus), revealing heterogeneous phylogenetically distinct RTEs triggered by epigenetic changes heat stress. Many these belong three groups within Tekay clade, showing significant variations chromosomal insertion distribution. Through protein analysis RTEs, it was found Athila group 2 elements additional open reading frames (aORFs). The aORF-encoded feature a transposase domain, transmembrane nuclear localization signals. aORF subgroup exhibited remarkable conservation among over 500 members, suggesting functional importance RTE mobility. predicted 3D structure sunflower showed homology with rice, maize, sorghum. Additionally, structural features resemble those DRBM-containing proteins, potential role RNA-silencing modulation. These findings offer insights into diversity activity emphasizing characteristics proteins.

Язык: Английский

The role of mobile DNA elements in the dynamic of plants genome plasticity DOI Creative Commons
Robyn Emmerson, Marco Catoni

Journal of Experimental Botany, Год журнала: 2025, Номер unknown

Опубликована: Янв. 10, 2025

Abstract Plants host a range of DNA elements capable self-replication. These molecules, usually associated to the activity transposable or viruses, are found integrated in genome form extrachromosomal DNA. The these can impact plasticity by variety mechanisms, including generation structural variants, shuffling regulatory coding sequences across genome, and endoduplication. This dynamically alter gene expression stability, ultimately affecting plant development response environmental changes. While activation is often considered deleterious their role creating variation important adaptation evolution. Moreover, mechanisms which mobile proliferate have been exploited for engineering, contributed understand how desirable traits be generated crops. In this review, we discuss origins roles element on biology, as well potential function current application biotechnology.

Язык: Английский

Процитировано

1

Toward Transgene-Free Transposon-Mediated Biological Mutagenesis for Plant Breeding DOI Open Access

Ilya Kirov

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(23), С. 17054 - 17054

Опубликована: Дек. 2, 2023

Genetic diversity is a key factor for plant breeding. The birth of novel genic and genomic variants also crucial adaptation in nature. Therefore, the genomes almost all living organisms possess natural mutagenic mechanisms. Transposable elements (TEs) are major force driving genetic wild plants modern crops. relatively rare TE transposition activity during thousand-year crop domestication process has led to phenotypic many cultivated species. utilization mutagenesis by artificial transient acceleration their controlled mode an attractive foundation type called TE-mediated biological mutagenesis. Here, I focus on TEs as sources breeding discuss existing emerging transgene-free approaches activation plants. Furthermore, review non-randomness insertions genome molecular epigenetic factors involved shaping insertion preferences. Additionally, mechanisms that prevent transpositions germline cells (e.g., meiocytes, pollen, egg embryo cells, shoot apical meristem), thereby reducing chances inheritance. Knowledge these can expand toolbox using gene targeting approaches. Finally, challenges future perspectives populations with induced (iTE collections) discussed.

Язык: Английский

Процитировано

7

Comparative Analysis of Active LTR Retrotransposons in Sunflower (Helianthus annuus L.): From Extrachromosomal Circular DNA Detection to Protein Structure Prediction DOI Open Access

Mikhail Kazancev,

Pavel Merkulov, Kirill N. Tiurin

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(24), С. 13615 - 13615

Опубликована: Дек. 19, 2024

Plant genomes possess numerous transposable element (TE) insertions that have occurred during evolution. Most TEs are silenced or diverged; therefore, they lose their ability to encode proteins and transposed in the genome. Knowledge of active plant TE-encoded essential for transposition evasion cell transposon silencing mechanisms remains limited. This study investigated long terminal repeat (LTR) retrotransposons (RTEs) sunflowers (Helianthus annuus), revealing heterogeneous phylogenetically distinct RTEs triggered by epigenetic changes heat stress. Many these belong three groups within Tekay clade, showing significant variations chromosomal insertion distribution. Through protein analysis RTEs, it was found Athila group 2 elements additional open reading frames (aORFs). The aORF-encoded feature a transposase domain, transmembrane nuclear localization signals. aORF subgroup exhibited remarkable conservation among over 500 members, suggesting functional importance RTE mobility. predicted 3D structure sunflower showed homology with rice, maize, sorghum. Additionally, structural features resemble those DRBM-containing proteins, potential role RNA-silencing modulation. These findings offer insights into diversity activity emphasizing characteristics proteins.

Язык: Английский

Процитировано

0