Spatial and temporal analysis on the impact of ultra-low volume indoor insecticide spraying on Aedes aegypti household density

Parasites & Vectors, Год журнала: 2024, Номер 17(1)

Опубликована: Июнь 11, 2024

Abstract Background Aedes aegypti is the primary mosquito vector for several arboviruses, such as dengue, chikungunya and Zika viruses, which cause frequent outbreaks of human disease in tropical subtropical regions. Control these relies on control, commonly form insecticide sprays that target adult female mosquitoes. However, spatial coverage frequency needed to optimize effectiveness are unclear. In this study, we characterize effect ultra-low-volume (ULV) indoor spraying pyrethroid insecticides Ae. abundance within households. We also evaluate effects spray events during recent time periods or neighboring Improved understanding duration distance impact a intervention populations can inform control interventions, addition modeling efforts contrast strategies. Methods This project analyzes data from two large-scale experiments involved six cycles applications 2 years Amazonian city Iquitos, Peru. developed multi-level models disentangle reduction resulted (i) ULV treatment households (ii) adjacent nearby compared fits across range candidate weighting schemes effect, based different temporal decay functions understand lagged effects. Results Our results suggested household was mainly due occurring same household, with no additional occurred Effectiveness should be measured since most event, found cumulative sequential sprays. Based our model, estimated reduced by 50% approximately 28 days after event. Conclusions The determined number last highlighting importance high-risk areas local viral transmission dynamics. Graphical abstract

Язык: Английский

Exploring The Dynamics of Gene Drive Mosquitoes Within Wild Populations Using an Agent-Based Simulation

Опубликована: Май 20, 2024

Язык: Английский