Bombyx prothoracicostatic peptides activate the sex peptide receptor to regulate ecdysteroid biosynthesis

Proceedings of the National Academy of Sciences, Год журнала: 2010, Номер 107(5), С. 2060 - 2065

Опубликована: Янв. 19, 2010

Insect molting and metamorphosis are induced by steroid hormones named ecdysteroids, whose production is regulated various neuropeptides. We cloned the gene analyzed expression of prothoracicostatic peptide, a unique neuropeptide shown to suppress ecdysteroids in prothoracic gland silkworm, Bombyx mori . also characterized G protein-coupled receptor, which has previously been identified as an ortholog Drosophila sex peptide functional receptor. This receptor responded specifically peptides when examined using heterologous system. The was highly expressed on day before each larval pupal ecdysis, synthesized at high level epiproctodeal glands. These results suggest that functions peripheral neurosecretory cells well central neuroendocrine system play stage-specific roles regulating ecdysteroidogenesis.

Язык: Английский

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Neuroendocrine Regulation of Ecdysis

Elsevier eBooks, Год журнала: 2011, Номер unknown, С. 253 - 309

Опубликована: Окт. 27, 2011

Язык: Английский

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Transcriptome Analysis of the Desert Locust Central Nervous System: Production and Annotation of a Schistocerca gregaria EST Database

PLoS ONE, Год журнала: 2011, Номер 6(3), С. e17274 - e17274

Опубликована: Март 21, 2011

Background The desert locust (Schistocerca gregaria) displays a fascinating type of phenotypic plasticity, designated as 'phase polyphenism'. Depending on environmental conditions, one genome can be translated into two highly divergent phenotypes, termed the solitarious and gregarious (swarming) phase. Although many underlying molecular events remain elusive, central nervous system (CNS) is expected to play crucial role in phase transition process. Locusts have also proven interesting model organisms physiological neurobiological research context. However, studies locusts are hampered by fact that genome/transcriptome sequence information available for this branch insects still limited. Methodology We generated 34,672 raw expressed tags (EST) from CNS both phases. These ESTs were assembled 12,709 unique transcript sequences nearly 4,000 functionally annotated. Moreover, obtained S. gregaria EST complementary existing orthopteran transcriptomic data. Since novel transcripts encode neuronal signaling signal transduction components, paper includes an overview these sequences. Furthermore, several being differentially represented retrieved database. findings highlight involvement process indicate annotated database may add emerging knowledge concomitant neuroplasticity events. Conclusions In summary, we met need data CNS. To our knowledge, hereby present first insect derived complete constitute important new source will instrumental further unraveling principles polyphenism, establishing valuable evolutionary comparative entomology.

Язык: Английский

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In silico cloning of genes encoding neuropeptides, neurohormones and their putative G-protein coupled receptors in a spider mite

Insect Biochemistry and Molecular Biology, Год журнала: 2011, Номер 42(4), С. 277 - 295

Опубликована: Дек. 30, 2011

Язык: Английский

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Does corazonin signal nutritional stress in insects?

Insect Biochemistry and Molecular Biology, Год журнала: 2009, Номер 39(11), С. 755 - 762

Опубликована: Окт. 7, 2009

Язык: Английский

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