Vitamin D and reproductive disorders: a comprehensive review with a focus on endometriosis
Reproductive Health,
Год журнала:
2024,
Номер
21(1)
Опубликована: Май 2, 2024
Abstract
Vitamin
D
is
a
fat-soluble
steroid
hormone
that
was
initially
known
only
for
regulating
calcium
and
phosphorus
levels
maintaining
bone
health.
However,
it
later
discovered
many
organs
express
vitamin
metabolizing
enzymes
have
ligand
D,
which
regulates
the
expression
of
an
extensive
assortment
genes.
As
result,
indispensable
proper
function
organs,
its
deficiency
believed
to
be
critical
factor
in
symptoms
disorders
such
as
cardiovascular
diseases,
autoimmune
cancers.
The
significance
reproductive
tissues
recognized
later,
studies
revealed
crucial
role
male
female
fertility,
well
during
pregnancy.
has
been
identified
risk
infertility,
gonadal
cancers,
pregnancy
complications,
polycystic
ovary
syndrome,
endometriosis.
data
investigating
association
between
disorders,
including
endometriosis,
encountered
inconsistencies.
Therefore,
present
study
aims
review
existing
research
on
effect
function,
diseases
specifically
focuses
Язык: Английский
Association of endometriosis with asthma: a study of the NHANES database in 1999–2006
Journal of Health Population and Nutrition,
Год журнала:
2024,
Номер
43(1)
Опубликована: Апрель 9, 2024
Abstract
Objective
Asthma
is
a
chronic
inflammatory
disease
of
the
airways
with
gender
differences
in
prevalence
after
puberty.
Recent
studies
have
reported
relationship
between
asthma
and
endometriosis,
possibly
related
to
immune
response
mechanisms,
but
evidences
are
limited
inconsistent.
Herein,
this
research
aimed
investigate
association
endometriosis
based
on
representative
population
United
States
(U.S.)
provide
some
reference
for
further
exploration
mechanism
difference
asthma.
Methods
In
cross-sectional
study,
data
women
aged
≥
20
years
old
were
extracted
from
National
Health
Nutrition
Examination
Survey
(NHANES)
database
1999–2006.
Weighted
univariate
multivariate
logistic
regression
analyses
utilized
explore
The
models
adjusted
covariates
including
age,
race,
education
level,
marital
status,
poverty
income
ratio
(PIR),
body
mass
index
(BMI),
waist
circumference,
smoking,
estrogen
progesterone
hormones
use,
uterine
fibroids,
at
least
one
ovary
removed,
birth
control
pills
intake.
evaluation
indexes
odds
ratios
(ORs)
95%
confidence
intervals
(CIs).
Subgroup
BMI,
pregnancy
history
also
performed.
Results
Among
5,556
eligible
women,
782
had
asthma,
380
endometriosis.
average
age
participants
was
37.19
old,
more
than
half
them
non-Hispanic
White
(68.44%).
After
adjusting
covariates,
associated
higher
compared
non-endometriosis
[OR
=
1.48,
95%CI:
(1.10–1.99)].
This
found
40–49
2.26,
(1.21–4.23)],
BMI
25-29.9
kg/m
2
2.87,
(1.52–5.44)],
1.44,
(1.01–2.06)]
subgroups.
Conclusion
Endometriosis
positive
adult
women.
Females
should
take
care
about
monitoring
reduce
potential
risk
Further
still
needed
clarify
causal
Язык: Английский
Effect of dietary patterns and nutritional supplementation in the management of endometriosis: a review
Frontiers in Nutrition,
Год журнала:
2025,
Номер
12
Опубликована: Март 12, 2025
Endometriosis
is
an
estrogen-dependent
chronic
inflammatory
disease
which
causes
dysmenorrhea,
pelvic
pain,
and
infertility
in
women
of
childbearing
age,
significantly
impacting
their
quality
life
physical
mental
health.
The
etiology
endometriosis
remains
unclear,
with
oxidative
stress
inflammation
currently
thought
to
play
pivotal
roles
its
pathophysiology.
Epidemiological
studies
clinical
trials
indicate
that
varying
dietary
patterns
specific
nutrient
supplementation
can
influence
markers
levels
factors
related
pathways,
potentially
the
progression
endometriosis.
In
this
review,
we
summarize
thoroughly
examine
current
understanding
effect
treating
This
study
suggests
nutrients
may
prevent
occurrence
by
modulating
factors,
regulating
angiogenesis,
influencing
metabolism
estrogen
pathways.
findings
might
provide
new
insights
into
treatment
patients
potential
benefits
Язык: Английский
Integrative Medicine in Women
Primary Care Clinics in Office Practice,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 1, 2025
The Importance of Diet in the Treatment of Endometriosis
Joanna Szczepanik,
Małgorzata Dłużewska
Women,
Год журнала:
2024,
Номер
4(4), С. 453 - 468
Опубликована: Ноя. 18, 2024
The
world
of
science
is
increasingly
looking
for
answers
to
the
question
how
specific
dietary
components
affect
risk
chronic
diseases
and
assessing
their
potential
alleviate
severity
individual
diseases.
This
research
concerns
both
assessment
benefits
using
those
nutritional
models.
Endometriosis,
due
its
inflammatory
nature,
also
a
topic
interest
among
scientists,
who
seek
support
course
through
proper
nutrition.
In
endometriosis,
great
focused
on
patterns
such
as
an
anti-inflammatory
diet,
gluten-free
low-FODMAP
or
Mediterranean
diet.
An
diet
primarily
focuses
fresh
vegetables,
fruits,
seeds,
nuts,
whole
grain
products,
healthy
sources
protein
fats,
including
mono-
polyunsaturated
fatty
acids,
eliminating
highly
processed
meat
trans
refined
sugars.
It
believed
that
this
type
may
contribute
reducing
endometriosis
symptoms
help
reduce
inflammation.
aim
review
identify
main
trends
in
field
diets
supporting
treatment
last
5
years.
Язык: Английский
Physiological characteristics of reproductive-age patients with female sexual dysfunction and endometriosis (a comparison of clinical and laboratory parameters in different study groups)
Zaporozhye Medical Journal,
Год журнала:
2024,
Номер
26(3), С. 210 - 216
Опубликована: Май 31, 2024
Endometriosis
is
an
estrogen-dependent
inflammatory
disease
that
affects
5–10
%
of
reproductive-age
women.
About
two-thirds
women
with
endometriosis
have
sexual
dysfunction
caused
by
dyspareunia,
which
negatively
the
quality
life
and
mental
health
a
woman.
The
aim
study
to
identify
differences
in
clinical
laboratory
parameters
groups
female
patients
obtaining
information
about
specifics
(FSD)
development
endometriosis.
Materials
methods.
examination
results
hormonal
profile,
functional
index
other
markers
were
analyzed
130
active
reproductive
age:
Group
I
(n
=
100)
–
main
group
manifestations
FSD
including
subgroup
IA
70)
external
genital
IB
30)
alone;
II
healthy
Results.
Women
combined
(IA)
exhibited
profile
different
from
(IB),
was
seen
significant
difference
follicle-stimulating
hormone
(FSH),
estradiol,
free
testosterone
dehydroepiandrosterone
sulfate
values
(p
0.001,
p
0.039,
0.035
0.035,
respectively).
Vitamin
D
deficiency
hyperhomocysteinemia,
presence
antibodies
thyroperoxidase
hyperprolactinemia
been
detected
all
signs,
regardless
concomitant
presence.
Post-hoc
analysis
(Mann–Whitney
test)
has
shown
mean
scores
for
categories
Female
Sexual
Function
Index
(FSFI)
questionnaire
statistically
significantly
higher
compared
those
<
0.001).
Conclusions.
characterized
increased
levels
FSH,
as
alone,
however
it
does
not
prevent
signs
them
accompanied
indicators
FSFI
domains.
Язык: Английский
Association Between Composite Dietary Antioxidant Index and Endometriosis from NHANES 2001–2006: A Cross-Sectional Study
International Journal of Women s Health,
Год журнала:
2024,
Номер
Volume 16, С. 1845 - 1854
Опубликована: Ноя. 1, 2024
Purpose:
To
evaluate
the
association
between
Composite
Dietary
Antioxidant
Index
(CDAI)
and
risk
of
endometriosis
in
American
women.
Methods:
The
study
adopted
a
cross-sectional
design,
incorporating
3862
women
aged
over
20
years,
selected
from
National
Health
Nutrition
Examination
Survey
(NHANES)
dataset
2001
to
2006.
Six
dietary
antioxidants
were
taken
into
account
calculating
CDAI.
Endometriosis
was
determined
based
on
self-report.
CDAI
endometriosis,
we
employed
models
with
multivariable
logistic
variables.
For
subgroup
assessment
relation
CDAI,
stratified
multivariate
regression
model
utilized.
Results:
Among
all
participants,
273
participants
(7.1%)
found
exhibit
endometriosis.
preliminary
analysis
showed
reverse
likelihood
(odds
ratio
[OR]
=
0.95;
95%
confidence
interval
[CI]:
0.92~0.98).
Upon
full
adjustment
within
regression,
ORs
(95%
CI)
for
prevalence
per
unit
increase
estimated
be
0.96
(0.93~1).
When
levels
divided
quartiles,
it
that
Q2
(−
2.131–
0.023),
Q3
(0.023–
2.650),
Q4
(2.650–
42.854)
0.74
(0.52,
1.05),
0.76
(0.53,
1.1),
0.53
(0.36,
0.79),
respectively,
compared
those
Q1
7.151–−
2.131).
We
evaluated
using
subgroups
by
age,
race/ethnicity,
education
level,
body
mass
index
(BMI),
oral
contraceptive,
menopausal
status,
revealing
substantial
negative
relationship.
Conclusion:
In
this
study,
increasing
proportionally
associated
reduced
among
women,
suggesting
diet
high
may
play
an
important
role
reducing
findings
NHANES
data
spanning
2006
suggest
promoting
antioxidant-rich
diets
could
prevention
strategy
Keywords:
composite
antioxidant
index,
Survey,
Язык: Английский
A cross-sectional study on the relationship between dietary fiber and endometriosis risk based on NHANES 1999–2006
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Ноя. 18, 2024
Endometriosis
is
a
chronic
inflammatory
disease
and
an
estrogen-dependent
disease,
so
dietary
factors
that
can
modulate
estrogen
activity
may
be
clinically
important.
Dietary
fiber,
widely
distributed
in
vegetables
fruits,
closely
associated
with
plant-based
diet.
Therefore,
this
study
aims
to
analyze
explore
the
relationship
between
fiber
intake
risk
of
endometriosis
providing
insights
for
future
clinical
significance
treatment
approaches.
This
cross-sectional
obtained
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
1999–2006
women
aged
20–54
years.
A
total
2840
subjects
were
finally
included
analysis,
2599
(91.51%)
non-endometriosis
group
241
(8.49%)
group.
The
used
fibre
as
exposure
variable
outcome
variable.
Through
use
multiple
regression
modelling,
subgroup
analyses,
smoothed
curve
fitting,
threshold
effect
tests,
we
uncovered
significant
link
outcome.
In
Model
2
(Multiple
equation
model
after
adjusting
all
confounding
variables),
confounders,
was
negatively
likelihood
developing
endometriosis(OR
=
0.588,
95%
CI
0.360–0.959,
p
0.041).
analyses
stratified
by
age,
race,
BMI,
educational
level,
hypertension,
diabetes,and
hyperlipidemia,
interactions
visualised
fitted
curves.
study,
connection
observed
higher
decreased
endometriosis.
Язык: Английский