Unraveling the Gut Microbiota: Implications for Precision Nutrition and Personalized Medicine
Nutrients,
Год журнала:
2024,
Номер
16(22), С. 3806 - 3806
Опубликована: Ноя. 6, 2024
Recent
studies
have
shown
a
growing
interest
in
the
complex
relationship
between
human
gut
microbiota,
metabolism,
and
overall
health.
This
review
aims
to
explore
microbiota-host
association,
focusing
on
its
implications
for
precision
nutrition
personalized
medicine.
The
objective
is
highlight
how
microbiota
modulate
metabolic
immune
functions,
contributing
disease
susceptibility
wellbeing.
synthesizes
recent
research
findings,
analyzing
key
influence
of
lipid
carbohydrate
intestinal
health,
neurobehavioral
regulation,
endocrine
signaling.
Data
were
drawn
from
both
experimental
clinical
trials
examining
interactions
relevant
nutrition.
Our
findings
essential
role
microbiota-derived
metabolites
regulating
host
including
glucose
pathways.
These
been
found
responses
barrier
integrity.
Additionally,
impacts
broader
physiological
processes,
neuroendocrine
which
could
be
crucial
dietary
interventions.
Therefore,
understanding
molecular
mechanisms
dietary-microbiota-host
pivotal
advancing
strategies.
Tailored
recommendations
based
individual
compositions
hold
promise
improving
health
outcomes,
potentially
revolutionizing
future
healthcare
approaches
across
diverse
populations.
Язык: Английский
Dietary Patterns, Gut Microbiota and Sports Performance in Athletes: A Narrative Review
Nutrients,
Год журнала:
2024,
Номер
16(11), С. 1634 - 1634
Опубликована: Май 26, 2024
The
intestinal
tract
of
humans
harbors
a
dynamic
and
complex
bacterial
community
known
as
the
gut
microbiota,
which
plays
crucial
role
in
regulating
functions
such
metabolism
immunity
human
body.
Numerous
studies
conducted
recent
decades
have
also
highlighted
significant
potential
microbiota
promoting
health.
It
is
widely
recognized
that
training
nutrition
strategies
are
pivotal
factors
allow
athletes
to
achieve
optimal
performance.
Consequently,
there
has
been
an
increasing
focus
on
whether
dietary
patterns
influence
sports
performance
through
their
impact
microbiota.
In
this
review,
we
aim
present
concept
primary
explore
relationship
between
exercise
specifically
examine
popular
associated
with
athletes'
while
considering
interaction
Finally,
discuss
mechanisms
by
affect
from
nutritional
perspective,
aiming
elucidate
intricate
interplay
among
patterns,
We
found
precise
application
specific
(ketogenic
diet,
plant-based
high-protein
Mediterranean
high
intake
carbohydrate)
can
improve
vascular
function
reduce
risk
illness
health
promotion,
etc.,
well
recovery
controlling
weight
regard
improving
performance,
etc.
conclusion,
although
it
be
inferred
certain
aspects
athlete's
ability
may
benefit
mediated
some
extent,
further
high-quality
clinical
warranted
substantiate
these
claims
underlying
mechanisms.
Язык: Английский
Gut Microbiota Alteration with Moderate-to-Vigorous-Intensity Exercise in Middle School Female Football Athletes
Biology,
Год журнала:
2025,
Номер
14(2), С. 211 - 211
Опубликована: Фев. 17, 2025
The
gut
microbiota
significantly
influences
health
and
metabolic
processes.
This
study
aimed
to
investigate
the
impact
of
exercise
intensity
on
middle
school
female
football
athletes.
In
this
four-week
controlled
comparative
study,
twenty-nine
participants
were
divided
into
three
groups:
non-exercise
group
(NEG),
moderate-intensity
(MIEG),
vigorous-intensity
(VIEG).
They
followed
their
respective
regimens
for
four
weeks.
Fecal
samples
collected
16S
rRNA
gene
sequencing
evaluate
composition.
MIEG
exhibited
greater
microbial
diversity
compared
NEG,
while
VIEG
showed
lower
than
MIEG.
Various
profiles
identified,
with
having
higher
levels
beneficial
bacteria
such
as
Bacteroides.
Moderate-intensity
promotes
a
healthier
vigorous
in
young
These
findings
underscore
potential
moderate
enhance
may
inform
training
strategies
adolescent
Язык: Английский
Gut Prevotella copri abundance linked to elevated post-exercise inflammation
Journal of sport and health science/Journal of Sport and Health Science,
Год журнала:
2025,
Номер
unknown, С. 101039 - 101039
Опубликована: Апрель 1, 2025
This
study
aimed
to
examine
the
linkage
between
gut
microbiome
taxa
and
exercise-induced
inflammation.
Twenty-five
cyclists
provided
4
stool
samples
during
a
10-week
period
cycled
vigorously
for
2.25
h
at
67%
maximal
oxygen
uptake
(VO2max)
in
laboratory
setting.
Blood
were
collected
pre-
post-exercise,
with
additional
1.5
h-,
3
24
h-post-exercise.
Primary
outcomes
included
composition
alpha
diversity
via
whole
genome
shotgun
(WGS)
sequencing
(averaged
from
samples)
targeted
panel
of
75
plasma
oxylipins.
A
total
5719
identified,
339
that
present
more
than
20%
used
analysis.
Alpha
was
calculated
by
evenness,
Analysis
Composition
Microbiomes
(ANCOM)
differential
abundance
analysis
performed
using
QIIME2.
composite
variable
8
pro-inflammatory
oxylipins
generated
arachidonic
acid
(ARA)
cytochrome
P-450
(CYP).
ARA-CYP
significantly
elevated
least
post-exercise
(p
<
0.001);
they
strongly
positively
related
Prevotella
copri
(P.
copri)
(R2
=
0.676,
p
0.001)
negatively
0.771,
0.001).
revealed
first
time
novel,
positive
relationship
P.
These
data
demonstrate
about
two-thirds
wide
variance
inflammation
following
prolonged
intensive
exercise
is
largely
explained
single
bacterial
species:
copri.
Язык: Английский
The Positive Effects of Training and Time-Restricted Eating in Gut Microbiota Biodiversity in Patients with Multiple Myeloma
Nutrients,
Год журнала:
2024,
Номер
17(1), С. 61 - 61
Опубликована: Дек. 27, 2024
Background:
The
physical
activity
of
different
groups
individuals
results
in
the
rearrangement
microbiota
composition
toward
a
symbiotic
profile.
This
applies
to
both
healthy
and
diseased
individuals.
Multiple
myeloma
(MM),
one
more
common
hematological
malignancies,
predominantly
affects
older
adults.
Identifying
an
appropriate
form
for
this
patient
group
remains
challenge.
aim
study
was
investigate
impact
6-week
Nordic
walking
(NW)
training
program
combined
with
10/14
time-restricted
eating
regimen
on
gut
multiple
patients.
Methods:
included
as
control
(n
=
16;
mean
age:
62.19
±
5.4)
patients
remission
(MM
group;
n
65.00
5.13;
disease
duration:
57
months).
intervention
applied
consisted
three
moderate-intensity
sessions
per
week,
individually
tailored
estimated
capacity
each
participant.
taxonomic
determined
via
16S
rRNA
sequencing
(V3–V9
regions).
compared
between
group.
Results:
alpha
beta
diversity
metrics
species
genus
levels
differed
significantly
before
implementation
NW
program.
In
contrast,
no
differences
were
observed
after
cycle,
indicating
that
patients’
changed
pattern
is
confirmed
by
lowest
values
average
dissimilarity
MMB
at
all
levels,
well
highest
MMA
represented
phyla
Firmicutes,
Actinobacteria,
Verrucomicrobia,
Proteobacteria,
Bacteroidetes.
Conclusions:
training,
eating,
stimulated
increase
biodiversity
species.
Язык: Английский
Особливості мікробіому спортсменів з аеробним механізмом енергозабезпечення
О. Л. Палладіна,
А. М. Каліга
Опубликована: Янв. 1, 2024
Актуальні
проблеми
фізичного
виховання,
спорту,
фізичної
реабілітації
та
туризму
у
сучасних
умовах
життя:
Матеріали
VI
між-народної
науково-практичної
конференції,
м.
Запоріжжя,
18–19
квітня
2024
р.
Львів
–
Торунь
:
Liha-Pres,
2024.
460
с.
DIFFERENCES IN THE MICROBIOME OF ATHLETES DEPENDING ON THE MECHANISM OF ENERGY SUPPLY OF MUSCLE ACTIVITY
Bulletin of Problems Biology and Medicine,
Год журнала:
2024,
Номер
1(1), С. 95 - 95
Опубликована: Янв. 1, 2024
The
human
gut
microbiome
significantly
impacts
physiological
and
biochemical
processes
in
the
body,
including
metabolism
immune
system.In
athletes,
it
may
also
contribute
to
increased
adaptive
capacity
endurance
improve
athletic
performance.So
far,
there
are
a
few
studies
on
of
athletes
different
sports,
most
which
investigate
differences
between
non-athletes.This
study
aims
determine
difference
microbial
composition
intestines
depending
type
energy
supply
for
muscle
activity.The
results
showing
changes
intestinal
various
aerobic
anaerobic
activity,
were
reviewed
detail.A
comparative
analysis
both
common
unique
bacterial
species
characteristic
with
supplies,
as
well
control
groups
people
(non-athletes),
was
conducted.Numerous
have
noted
an
increase
faecal
short-chain
fatty
acids
(SCFAs)
origin
can
be
substrates
gluconeogenesis
lipogenesis
expression
large
intestine
genes
involved
response.The
samples
marathon
runners
enriched
Veillonella
atypica,
capable
metabolising
lactate
into
acetate
propionate
SCFAs
using
methylmalonyl-CoA.The
Firmicutes/Bacteroides
ratio
has
been
shown
associated
higher
VO₂max
when
increases.The
data
obtained
vary
design
number
participants,
indicates
significant
difficulties
determining
biodiversity
athletes'
identifying
many
factors.Nevertheless,
findings
highlight
potential
link
microbiota
types
activity
during
exercise
indicate
symbiotic
relationship
adaptation
these
systems.
Язык: Английский
Gut Microbiome Modulation of Innate Immunity in Neurodegenerative Diseases
Oxford University Press eBooks,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 19, 2024
Abstract
The
intimate
connections
among
the
gut,
immune
system,
and
brain
have
become
increasingly
apparent
in
recent
years.
Alterations
gut
microbiome
been
reported
several
neurodegenerative
diseases
including
Alzheimer’s
disease,
Parkinson’s
multiple
sclerosis.
Moreover,
evidence
also
points
to
innate
system
involvement
pathogenesis
of
these
diseases.
Given
that
is
largest
organ
body,
understanding
dynamic
interplay
between
how
this
influences
health
disease
critical.
Further
microbiome,
their
interactions
are
altered
may
be
key
developing
disease-modifying
therapies.
This
chapter
reviews
literature
related
microbiome-derived
mediators
impact
on
context
external
factors,
diet,
pre-/probiotics,
exercise,
caffeine,
smoking,
immunity
discussed.
Язык: Английский
Microbial Champions: The Influence of Gut Microbiota on Athletic Performance via the Gut-Brain Axis
Open Access Journal of Sports Medicine,
Год журнала:
2024,
Номер
Volume 15, С. 209 - 228
Опубликована: Дек. 1, 2024
In
recent
years,
exercise
has
shown
a
powerful
ability
to
regulate
the
gut
microbiota
received
with
concern.For
instance,
compared
sedentary
group,
high-level
athletes
showed
different
composition
and
remarkable
capability
of
physiological
metabolism.In
addition,
diet
patterns
(eg,
high-fat
diet,
high
carbohydrate
et.al)
have
effects
on
microbiota,
which
can
also
affect
performance.Furthermore,
adaptations
might
be
influenced
by
due
its
important
role
in
transformation
expenditure
energy
obtained
from
diet.Therefore,
appropriate
dietary
supplementation
is
during
exercise.And
exploring
mechanisms
supplements
performance
modulating
considerable
interest
wishing
achieve
health
athletic
performance.In
this
narrative
review,
relationship
between
supplements,
training
discussed
as
follows.(i)
The
three
main
nutritional
athlete
fitness.(ii)
Strategies
for
how
they
exerted
function
through
alteration
based
gut-brain
axis.(iii)
Why
supplement
interventions
should
tailored
types
exercise.Our
work
integrates
these
factors
elucidate
specific
modulate
and,
consequently,
influence
outcomes,
unlike
previous
literature
that
often
focuses
solely
or
independently.And
provides
comprehensive
framework
seeking
optimize
their
microbiota-centric
approach.
Язык: Английский