Association between geriatric nutritional risk index and overactive bladder in the elderly population: a cross-sectional study
Frontiers in Nutrition,
Год журнала:
2025,
Номер
12
Опубликована: Фев. 11, 2025
Background
The
prevalence
of
overactive
bladder
(OAB)
is
increasing
in
the
elderly
population
and
there
growing
evidence
that
malnutrition
affects
urinary
system.
Despite
this,
research
on
relationship
between
nutritional
factors
OAB
remains
limited.
Methods
We
included
17,161
individuals
from
National
Health
Nutrition
Examination
Survey
conducted
2005
2018.
Overactive
Bladder
Symptom
Scores
(OABSS)
were
utilized
to
assess
symptoms
OAB.
A
multifactorial
logistic
regression
analysis
was
employed
evaluate
independent
association
Geriatric
Nutritional
Risk
Index
(GNRI)
Restricted
cubic
spline
plots
examined
potential
non-linear
GNRI
Influencing
assessed
through
subgroup
analyses,
while
predictive
utility
with
receiver
operating
characteristic
(ROC)
curves.
influence
inflammatory
response
cognitive
function
interaction
also
by
mediation
analysis.
Results
group
significantly
lower
than
non-OAB
group.
Multifactorial
revealed
predicts
(
p
<
0.05).
Cubic
Spline
(RCS)
curve
indicated
a
negative
correlation
risk
(non-linear
=
0.0029).
In
analysis,
outperforms
serum
albumin
or
body
mass
index
(BMI)
alone
predicting
risk.
study
mediates
OAB,
has
relatively
weaker
strength
Conclusion
serves
as
reliable
marker
for
population,
demonstrating
nonlinear
inverse
prevalence.
Furthermore,
this
elucidates
underlying
mechanisms
link
development
Язык: Английский
Association between systemic immune inflammation index and adolescent obesity in a cross-sectional analysis
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Фев. 22, 2025
Abstract
Obesity
is
a
prevalent
health
issue
among
adolescents,
characterized
by
chronic
low-grade
inflammation,
which
increases
the
risk
of
developing
various
diseases
in
future.
The
systemic
immune-inflammation
index
(SII)
serves
as
an
indicator
inflammation
and
immune
response.
This
study
conducted
cross-sectional
analysis
using
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
2007
to
2016,
including
5,676
participants.
A
multivariate
logistic
regression
model,
Generalized
Additive
Models
(GAM),
subgroup
were
used
examine
relationship
between
obesity
SII.
results
revealed
significant
positive
correlation
log
SII
adolescent
(1.254
[1.024–1.537]).
Furthermore,
increased
with
higher
quartiles
Subgroup
interaction
tests
showed
that
this
association
persisted
across
factors,
female
gender,
race
(Non-Hispanic
White
Mexican
American),
non-hyperlipidemia,
normal
white
blood
cell
count,
PIR
<
1.
Additionally,
U-shaped
was
observed,
turning
point
at
6.410.
findings
suggest
increase
significantly
associated
adolescents.
However,
further
validation
through
large-scale
prospective
studies
needed.
Язык: Английский
Association between family income to poverty ratio and severe headache/migraine in the American adults: data from NHANES 1999–2004
Frontiers in Neurology,
Год журнала:
2024,
Номер
15
Опубликована: Ноя. 18, 2024
Background
The
relationship
between
family
income
to
poverty
ratio
(PIR)
and
severe
headache/migraine
remains
unclear.
Methods
Data
for
this
cross-sectional
study
were
obtained
from
NHANES
1999–2004.
PIR
was
the
exposure
variable,
dependent
variable.
We
performed
univariate
analyses
of
headache/migraine,
PIR,
other
covariates.
association
tested
using
multiple
regression
models.
Furthermore,
interaction
tests
stratified
assessed
across
subgroups.
Results
There
a
total
8,800
participants:
4,833
(54.92%)
males
3,967
(45.08%)
females,
1,714
(19.48%)
with
7,086
(80.52%)
without
headache/migraine.
After
adjustment
all
variables,
negatively
correlated
OR
=
0.86
95%
CI
(0.83,
0.90)
p
<
0.0001.
variable
categorized
as
low-income
(PIR
1),
middle-income
(PIR1-4),
high-income
>
4).
Notably,
there
significant
difference
in
trend
group
4)
compared
control
1)
(all
P
interaction<0.05).
Dose–response
correlations
also
analyzed
smoothed
curve
fitting,
revealing
negative
correlation
(
0.0001).
Subgroup
analysis
results
indicated
that
more
pronounced
following
populations:
(OR
0.84
(0.79,
0.90),
<60
years
old
[Age
45
0.81
(0.76,
0.85)],
Age
45–60
0.93),
those
education
levels
≥high
school
[High
School
0.87
(0.81,
0.95),
>High
0.82
(0.78,
0.87)].
Conclusion
is
incidence
headaches/
migraine
Americans
aged
20
or
older.
This
has
implications
comprehensive
management
patients
Язык: Английский