Influence of COVID-19 public health restrictions on community-acquired pneumonia pathogens in children in Henan, China: a multicenter retrospective study DOI Creative Commons

Yalin Guo,

Debin Yang,

Yang Cao

и другие.

BMC Infectious Diseases, Год журнала: 2024, Номер 24(1)

Опубликована: Дек. 3, 2024

To investigate the distribution of pathogens and epidemiological changes in children hospitalized with community-acquired pneumonia (CAP) during after COVID-19 pandemic public health restrictive measures. aiming to provide a foundation for clinical diagnosis, treatment, policy formulation. This multicenter retrospective study spanned January 2019 December 2023. The included 78,256 CAP four hospitals Henan, China, among which 27,580 cases (35.2%) were tested using multiplex real-time fluorescent polymerase chain reaction (PCR). detected include Streptococcus pneumoniae (SP), Staphylococcus aureus (SA), Haemophilus influenzae (HI), respiratory syncytial virus (RSV), influenza A (Flu A), B B), Mycoplasma (MP). Pathogens identified 18,690 children, resulting 67.8% positive detection rate. Of these cases, 15,105 (54.8%) single pathogen infections 3,585 (13%) mixed infections. positivity rate was lowest first year (2020), at 54.7%, peaked 79.1% 2023, restrictions lifted. During (2020–2022), seasonal variation prevalence disrupted. Post-restriction, there significant increase RSV MP cases. SP remained leading bacterial cause CAP, especially young children. predominant viral pathogen, particularly affecting infants. showed rising trend age, yet it also affected younger individuals. altered characteristics CAP. impact is likely persist, necessitating enhanced surveillance mitigate healthcare burden Not applicable.

Язык: Английский

An Overview of Macrolide Resistance in Streptococci: Prevalence, Mobile Elements and Dynamics DOI Creative Commons
Dámaris Berbel, Aida González-Díaz, Guillem López de Egea

и другие.

Microorganisms, Год журнала: 2022, Номер 10(12), С. 2316 - 2316

Опубликована: Ноя. 23, 2022

Streptococcal infections are usually treated with beta-lactam antibiotics, but, in case of allergic patients or reduced antibiotic susceptibility, macrolides and fluoroquinolones the main alternatives. This work focuses on studying macrolide resistance rates, genetic associated determinants consumption data Spain, Europe also a global scale. Macrolide (MR) determinants, such as ribosomal methylases (

Язык: Английский

Процитировано

34
Influence of COVID-19 public health restrictions on community-acquired pneumonia pathogens in children in Henan, China: a multicenter retrospective study DOI Creative Commons

Yalin Guo,

Debin Yang,

Yang Cao

и другие.

BMC Infectious Diseases, Год журнала: 2024, Номер 24(1)

Опубликована: Дек. 3, 2024

To investigate the distribution of pathogens and epidemiological changes in children hospitalized with community-acquired pneumonia (CAP) during after COVID-19 pandemic public health restrictive measures. aiming to provide a foundation for clinical diagnosis, treatment, policy formulation. This multicenter retrospective study spanned January 2019 December 2023. The included 78,256 CAP four hospitals Henan, China, among which 27,580 cases (35.2%) were tested using multiplex real-time fluorescent polymerase chain reaction (PCR). detected include Streptococcus pneumoniae (SP), Staphylococcus aureus (SA), Haemophilus influenzae (HI), respiratory syncytial virus (RSV), influenza A (Flu A), B B), Mycoplasma (MP). Pathogens identified 18,690 children, resulting 67.8% positive detection rate. Of these cases, 15,105 (54.8%) single pathogen infections 3,585 (13%) mixed infections. positivity rate was lowest first year (2020), at 54.7%, peaked 79.1% 2023, restrictions lifted. During (2020–2022), seasonal variation prevalence disrupted. Post-restriction, there significant increase RSV MP cases. SP remained leading bacterial cause CAP, especially young children. predominant viral pathogen, particularly affecting infants. showed rising trend age, yet it also affected younger individuals. altered characteristics CAP. impact is likely persist, necessitating enhanced surveillance mitigate healthcare burden Not applicable.

Язык: Английский

Процитировано

1