Postural stability and plantar pressure parameters in healthy subjects: variability, correlation analysis and differences under open and closed eye conditions DOI Creative Commons
Paolo De Blasiis, Paolo Caravaggi, Allegra Fullin

и другие.

Frontiers in Bioengineering and Biotechnology, Год журнала: 2023, Номер 11

Опубликована: Июль 20, 2023

Introduction: The “postural control system” acts through biomechanical strategies and functional neuromuscular adaptations to maintain body balance under static dynamic conditions. Postural stability weight distribution can be affected by external sensory inputs, such as different visual stimuli. Little information is available about the influence of receptors on stabilometric plantar pressure parameters. aim this study was analyze variability, correlations, changes in these parameters open- (OE) closed-eye (CE) Methods: A total 31 were acquired 20 young healthy adults during baropodometric examination performed bipedal standing both Variability evaluated via coefficient variation, correlation analysis Pearson’s R2, statistical differences Wilcoxon test. Results: High intra-subject repeatability found for all CoP-speed (CV < 40%) OE CE conditions, while CoP-sway area (CoPsa) length surface function (LSF) showed larger variability > 50%). Mean peak pressures at midfoot foot loads least number significant correlations with other whereas arch-index rearfoot largest correlations. limb side significantly most trend LSF lower CoPsa mean right forefoot condition. Discussion: present provides a deeper insight into associations between postural load. Interesting adaptations, particularly respect stimuli, effect dominant side, specific role highlighted.

Язык: Английский

Gender-related differences in neural responses to gaming cues before and after gaming: implications for gender-specific vulnerabilities to Internet gaming disorder DOI Creative Commons
Guangheng Dong, Lingxiao Wang, Xiaoxia Du

и другие.

Social Cognitive and Affective Neuroscience, Год журнала: 2018, Номер 13(11), С. 1203 - 1214

Опубликована: Сен. 25, 2018

More males than females play video games and develop problems with gaming. However, little is known regarding how who game on the Internet may differ respect to neural responses gaming cues. Behavioral functional magnetic resonance imaging (fMRI) data were recorded from 40 female 68 male gamers. This study included three components including participation in a pre-gaming cue-craving task, 30 min of online post-gaming cue-elicited-craving task. Group differences examined at pre-gaming, post- vs times. Correlations between brain behavioral performance calculated. Gaming-related cues elicited higher cravings subjects. Prior gaming, demonstrated greater activations striatum, orbitofrontal cortex (OFC), inferior frontal bilateral declive. Following subjects medial gyrus middle temporal gyri. In post–pre comparison, thalamic activation did Short-term more craving-related These results suggest mechanisms for why be vulnerable developing disorder.

Язык: Английский

Процитировано

110
A Roadmap to Inform Development, Validation and Approval of Digital Mobility Outcomes: The Mobilise-D Approach DOI Creative Commons
Lynn Rochester, Claudia Mazzà, Arne Mueller

и другие.

Digital Biomarkers, Год журнала: 2020, Номер 4(Suppl. 1), С. 13 - 27

Опубликована: Ноя. 26, 2020

Health care has had to adapt rapidly COVID-19, and this in turn highlighted a pressing need for tools facilitate remote visits monitoring. Digital health technology, including body-worn devices, offers solution using digital outcomes measure monitor disease status provide meaningful both patients professionals. Remote monitoring of physical mobility is prime example, because among the most advanced modalities that can be assessed digitally remotely. Loss also an important feature many conditions, providing read-out as well target intervention. Real-world, continuous measures (digital or DMOs) opportunity novel insights into conditions complementing existing measures. Accepted approved DMOs are not yet widely available. The large collaborative efforts tackle critical steps adoption recognised. Mobilise-D example. It multidisciplinary consortium 34 institutions from academia industry funded through European Innovative Medicines Initiative 2 Joint Undertaking. Members collaborating address adopted clinical trials ultimately care. To achieve this, developed roadmap inform development, validation approval Parkinson’s disease, multiple sclerosis, chronic obstructive pulmonary recovery proximal femoral fracture. Here we aim describe proposed approach high-level view ongoing planned work consortium. Ultimately, aims stimulate widespread provision device agnostic software, standards robust order bring concept use

Язык: Английский

Процитировано

106
What are the association patterns between handgrip strength and adverse health conditions? A topical review DOI Creative Commons
Ryan McGrath, Nathaniel Johnson,

Lukus Klawitter

и другие.

SAGE Open Medicine, Год журнала: 2020, Номер 8

Опубликована: Янв. 1, 2020

Measures of handgrip strength can be used to conveniently assess overall muscle capacity. Although stand-alone measures provide robust health information, the clinical meaningfulness determine prevention and treatment options for weakness remains limited because etiology unclear. Moreover, outcomes associated with are wide-ranging. Therefore, disentangling how is conditions that metabolically or neurologically driven may improve our understanding factors linked strength. The purpose this topical review was highlight summarize evidence examining associations certain driven. From perusal literature, we posit considered an umbrella assessment body systems contribute capacity, a panoptic measurement representative status, not specific condition. Recommendations future capacity–related research also provided.

Язык: Английский

Процитировано

97
The sensory role of the sole of the foot: Review and update on clinical perspectives DOI
Frédéric Viseux

Neurophysiologie Clinique, Год журнала: 2020, Номер 50(1), С. 55 - 68

Опубликована: Янв. 29, 2020

Язык: Английский

Процитировано

96
Managing Gait, Balance, and Posture in Parkinson’s Disease DOI
Bettina Debû, Clécio Godeiro‐Júnior,

Jarbas Correa Lino

и другие.

Current Neurology and Neuroscience Reports, Год журнала: 2018, Номер 18(5)

Опубликована: Апрель 6, 2018

Язык: Английский

Процитировано

93
Fifteen Years of Wireless Sensors for Balance Assessment in Neurological Disorders DOI Creative Commons
Alessandro Zampogna, Ilaria Mileti, Eduardo Palermo

и другие.

Sensors, Год журнала: 2020, Номер 20(11), С. 3247 - 3247

Опубликована: Июнь 7, 2020

Balance impairment is a major mechanism behind falling along with environmental hazards. Under physiological conditions, ageing leads to progressive decline in balance control per se. Moreover, various neurological disorders further increase the risk of falls by deteriorating specific nervous system functions contributing balance. Over last 15 years, significant advancements technology have provided wearable solutions for evaluation and management postural instability patients disorders. This narrative review aims address topic wireless sensors several disorders, including Alzheimer’s disease, Parkinson’s multiple sclerosis, stroke, other neurodegenerative acute clinical syndromes. The discusses pathophysiological bases as well traditional innovative instruments currently available assessment. technical perspectives technologies, current challenges field teleneurology, are also examined.

Язык: Английский

Процитировано

92
Central pattern generators in the brainstem and spinal cord: an overview of basic principles, similarities and differences DOI

Inge Steuer,

Pierre A. Guertin

Reviews in the Neurosciences, Год журнала: 2018, Номер 30(2), С. 107 - 164

Опубликована: Дек. 13, 2018

Central pattern generators (CPGs) are generally defined as networks of neurons capable enabling the production central commands, specifically controlling stereotyped, rhythmic motor behaviors. Several CPGs localized in brainstem and spinal cord areas have been shown to underlie expression complex behaviors such deglutition, mastication, respiration, defecation, micturition, ejaculation, locomotion. Their pivotal roles clearly demonstrated although their organization cellular properties remain incompletely characterized. In recent years, insightful findings about made mainly because (1) several complementary animal models were developed; (2) these enabled a wide variety techniques be used and, hence, plethora characteristics discovered; (3) organizations, functions, cell across all species studied thus far found well-preserved phylogenetically. This article aims at providing an overview for non-experts most important on vivo models, vitro preparations from invertebrate vertebrate well primates. Data CPG adaptation, organization, will summarized with special attention paid network locomotion given its advanced level characterization compared some other CPGs. Similarities differences between also highlighted.

Язык: Английский

Процитировано

91
Gait DOI
Anat Mirelman,

Shirley Shema,

Inbal Maidan

и другие.

Handbook of clinical neurology, Год журнала: 2018, Номер unknown, С. 119 - 134

Опубликована: Янв. 1, 2018

Язык: Английский

Процитировано

91
Neuroimaging advances in Parkinson's disease with freezing of gait: A systematic review DOI Creative Commons
Komal Bharti, Antonio Suppa, Silvia Tommasin

и другие.

NeuroImage Clinical, Год журнала: 2019, Номер 24, С. 102059 - 102059

Опубликована: Янв. 1, 2019

Freezing of gait (FOG) is a paroxysmal disorder that often occurs at advanced stages Parkinson's disease (PD). FOG consists abrupt walking interruption and severe difficulty in locomotion with an increased risk falling. Pathophysiological mechanisms underpinning PD are still unclear. However, MRI nuclear medicine studies have gained relevant insights into the pathophysiology PD. Neuroimaging demonstrated structural functional abnormalities number cortical subcortical brain regions patients FOG. In this paper, we systematically review existing neuroimaging literature on changes described FOG, according to Preferred Reporting Items for Systematic Reviews Meta-Analyses guidelines. We evaluate previous using various techniques estimate grey matter loss white degeneration. Moreover, by examining imaging studies. The current provides up-to-date knowledge field summarizes possible responsible

Язык: Английский

Процитировано

79
The brain-body disconnect: A somatic sensory basis for trauma-related disorders DOI Creative Commons
Breanne E. Kearney, Ruth A. Lanius

Frontiers in Neuroscience, Год журнала: 2022, Номер 16

Опубликована: Ноя. 21, 2022

Although the manifestation of trauma in body is a phenomenon well-endorsed by clinicians and traumatized individuals, neurobiological underpinnings this remain unclear. The notion somatic sensory processing, which encompasses vestibular somatosensory processing relates to systems concerned with how physical exists space, introduced as major contributor overall regulatory, social-emotional, self-referential functioning. From phylogenetically ontogenetically informed perspective, trauma-related symptomology conceptualized be grounded brainstem-level dysfunction its cascading influences on physiological arousal modulation, affect regulation, higher-order capacities. Lastly, we introduce novel hierarchical model bridging processes limbic neocortical mechanisms regulating an individual’s emotional experience sense relational, agentive self. This provides working framework for neurobiologically assessment treatment conditions from perspective.

Язык: Английский

Процитировано

67