From Wuhan to Omicron K.P2 strain: A comprehensive review of SARS-CoV-2 phylogeny and public health implications of the latest booster vaccine

Human Vaccines & Immunotherapeutics, Год журнала: 2025, Номер 21(1)

Опубликована: Апрель 11, 2025

The SARS-CoV-2 virus continues to evolve, with the Omicron KP.2 variant, a descendant of BA.2.86, emerging as public health concern due its rapid spread and resistance existing immunity. This review examines phylogenetic evolution SARS-CoV-2, focusing on key mutations (R346T, F456L, V1104L), alongside epidemiological implications. It also discusses development approval KP.2-adapted booster vaccine, shown in clinical trials significantly enhance immune responses protect against symptomatic severe disease, particularly vulnerable groups. Despite vaccine advancements, challenges global distribution inequity persist, especially low- middle-income countries, increasing risk vaccine-resistant variants. manuscript underscores importance equitable access control pandemic prevent future outbreaks, while highlighting need for continuous surveillance broader-spectrum research evolves.

Язык: Английский

Evaluation of neutralizing antibody titers against SARS-CoV-2 JN.1 Omicron subvariant during pregnancy - A case series study

Heliyon, Год журнала: 2024, Номер 11(1), С. e41249 - e41249

Опубликована: Дек. 19, 2024

Язык: Английский