bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Июль 29, 2023
Abstract
When
holding
visual
information
temporarily
in
working
memory
(WM),
the
neural
representation
of
memorandum
is
distributed
across
various
cortical
regions,
including
and
frontal
cortices.
However,
role
stimulus
cortices
during
WM
has
been
controversial.
Here
we
tested
hypothesis
that
persists
cortex
to
facilitate
flexible
control
demands
WM.
During
functional
MRI,
participants
flexibly
switched
between
simple
maintenance
or
more
complex
rule-based
categorization
maintained
on
a
trial-by-trial
basis.
Our
results
demonstrated
enhanced
tracked
for
active
precise
maintenance.
This
differential
traded
off
with
newly-generated
category
varying
demands.
Simulation
using
multi-module
recurrent
networks
replicated
human
patterns
when
was
preserved
network
readout.
Altogether,
these
findings
help
reconcile
long-standing
debate
research,
provide
empirical
computational
evidence
serves
as
potential
coding
scheme
accommodate
ever-changing
environment.
PLoS Biology,
Год журнала:
2024,
Номер
22(10), С. e3002863 - e3002863
Опубликована: Окт. 28, 2024
Animals
guide
their
behaviors
through
internal
representations
of
the
world
in
brain.
We
aimed
to
understand
how
macaque
brain
stores
such
general
knowledge,
focusing
on
object
color
knowledge.
Three
functional
magnetic
resonance
imaging
(fMRI)
experiments
were
conducted
monkeys:
viewing
chromatic
and
achromatic
gratings,
grayscale
images
familiar
fruits
vegetables
(e.g.,
strawberry),
true-
false-colored
objects
red
strawberry
green
strawberry).
observed
robust
knowledge
patches,
especially
one
located
around
TEO:
activity
patterns
could
classify
pictures
based
memory
response
these
regions
translate
between
grating
grating—grayscale
that
classifiers
trained
by
gratings
successfully
according
colors.
Our
results
showed
direct
positive
evidence
monkeys.
These
indicate
perceptually
grounded
representation
as
a
conservative
mechanism
open
new
avenue
study
this
particular
(semantic)
with
models.
Brain Sciences,
Год журнала:
2024,
Номер
14(8), С. 757 - 757
Опубликована: Июль 28, 2024
Flexible
pulse-by-pulse
regulation
of
sensorimotor
synchronization
is
crucial
for
voluntarily
showing
rhythmic
behaviors
synchronously
with
external
cueing;
however,
the
underpinning
neurophysiological
mechanisms
remain
unclear.
We
hypothesized
that
dorsal
anterior
cingulate
cortex
(dACC)
plays
a
key
role
by
coordinating
both
proactive
and
reactive
motor
outcomes
based
on
contextual
mental
imagery.
To
test
our
hypothesis,
missing-oddball
task
in
finger-tapping
paradigms
was
conducted
33
healthy
young
volunteers.
The
dynamic
properties
dACC
were
evaluated
event-related
deep-brain
activity
(ER-DBA),
supported
potential
(ERP)
analysis
behavioral
evaluation
signal
detection
theory.
found
ER-DBA
activation/deactivation
reflected
strategic
choice
control
modality
accordance
Reverse
ERP
traces,
as
omission
responses,
confirmed
imagery
contextual.
updated
only
environmental
changes
via
perceptual
evidence
response-based
abductive
reasoning.
Moreover,
stable
on-pulse
tapping
achievable
maintaining
while
creating
an
syncopated
rhythms
from
simple
beat
trains,
whereas
accuracy
degraded
frequent
erroneous
missing
pulses.
conclude
regulates
utilizing
experience
novel
rhythms.
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Июль 29, 2023
Abstract
When
holding
visual
information
temporarily
in
working
memory
(WM),
the
neural
representation
of
memorandum
is
distributed
across
various
cortical
regions,
including
and
frontal
cortices.
However,
role
stimulus
cortices
during
WM
has
been
controversial.
Here
we
tested
hypothesis
that
persists
cortex
to
facilitate
flexible
control
demands
WM.
During
functional
MRI,
participants
flexibly
switched
between
simple
maintenance
or
more
complex
rule-based
categorization
maintained
on
a
trial-by-trial
basis.
Our
results
demonstrated
enhanced
tracked
for
active
precise
maintenance.
This
differential
traded
off
with
newly-generated
category
varying
demands.
Simulation
using
multi-module
recurrent
networks
replicated
human
patterns
when
was
preserved
network
readout.
Altogether,
these
findings
help
reconcile
long-standing
debate
research,
provide
empirical
computational
evidence
serves
as
potential
coding
scheme
accommodate
ever-changing
environment.
