The resting-state brain activity signatures for addictive disorders

Med, Год журнала: 2024, Номер 5(3), С. 201 - 223.e6

Опубликована: Фев. 14, 2024

Язык: Английский

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Mobile phone short video use negatively impacts attention functions: an EEG study

Frontiers in Human Neuroscience, Год журнала: 2024, Номер 18

Опубликована: Июнь 27, 2024

The pervasive nature of short-form video platforms has seamlessly integrated into daily routines, yet it is important to recognize their potential adverse effects on both physical and mental health. Prior research identified a detrimental impact excessive consumption attentional behavior, but the underlying neural mechanisms remain unexplored. In current study, we aimed investigate effect use functions, measured through attention network test (ANT). A total 48 participants, consisting 35 females 13 males, with mean age 21.8 years, were recruited. mobile phone short addiction tendency questionnaire (MPSVATQ) self-control scale (SCS) conducted assess usage behavior ability. Electroencephalogram (EEG) data recorded during completion ANT task. correlation analysis showed significant negative relationship between MPSVATQ theta power index reflecting executive control in prefrontal region ( r = −0.395, p 0.007), this result was not observed by using resting-state EEG data. Furthermore, SCS outcomes −0.320, 0.026). These results suggest that an increased toward could negatively diminish within realm functions. This study sheds light consequences stemming from underscores importance developing interventions mitigate addiction.

Язык: Английский

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Opioid modulation of prefrontal cortex cells and circuits

Neuropharmacology, Год журнала: 2024, Номер 248, С. 109891 - 109891

Опубликована: Фев. 27, 2024

Several neurochemical systems converge in the prefrontal cortex (PFC) to regulate cognitive and motivated behaviors. A rich network of endogenous opioid peptides receptors spans multiple PFC cell types circuits, this extensive system has emerged as a key substrate underlying reward, motivation, affective behaviors, adaptations stress. Here, we review current evidence for dysregulated cortical signaling pathogenesis psychiatric disorders. We begin by providing an introduction basic anatomy function system, followed discussion exogenous modulation at behavioral, cellular, synaptic level. Finally, highlight therapeutic potential targets treatment disorders, synthesizing clinical reports altered peptide receptor expression activity human patients summarizing new developments opioid-based medications. This article is part Special Issue on "PFC circuit disease relevant models".

Язык: Английский

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Exploring social impairment in those with opioid use disorder: linking impulsivity, childhood trauma, and the prefrontal cortex

BMC Psychiatry, Год журнала: 2025, Номер 25(1)

Опубликована: Март 3, 2025

Abstract Background Challenges with social functioning, which is a hallmark of opioid use disorder (OUD), are drawback in treatment adherence and maintenance. Yet, little research has explored the underlying mechanisms this impairment. Impulsivity corresponding neural alterations may be at center issue. Childhood adversity, been linked to both impulsivity poorer outcomes, could also affect relationship. This study explores relationship between impulsivity, their correlates prefrontal cortex, while examining potential moderating effects childhood trauma individuals recovering from OUD. Methods Participants ( N = 16) without 19) impairment completed survey (e.g., Barrat’s Scale, Adverse Experiences (ACEs) cognitive tasks undergoing neuroimaging. Functional near infrared spectroscopy (fNIRS), modern, portable, wearable low-cost neuroimaging technology, was used measure cortex activity during behavioral inhibition task (Go/No-Go task). Results Those who functioning scores indicated n scored significantly higher on scale (t [33]= -3.4, p < 0.01) reported more depressive symptoms [33] -2.8, than those reporting no 19). Social negatively correlated r =-0.7, 0.001), such that increased corresponded decreased functioning. emerged as moderator relationship, but only when controlling for depression, B=-0.11, 0.023. Although groups had comparable Go/No-Go performance, socially impaired group displayed greater activation dorsolateral (F(1,100.8) 7.89, 0.01), ventrolateral (F(1,88.8) 7.33, ventromedial (F(1,95.6) 7.56, duringthe task. Conclusion In addition being impulsive, exhibited Furthermore, impact varies depending ACEs, levels ACEs stronger negative highlighting its importance approaches. These findings have implications addressing needs recovery, personalized, integrative, trauma-informed approach intervention.

Язык: Английский

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Neuropsychological Assessment of Substance Use Disorders

Опубликована: Янв. 1, 2025

Язык: Английский

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Whole-brain resting-state connectivity underlying impaired inhibitory control during early versus longer-term abstinence in cocaine addiction

Molecular Psychiatry, Год журнала: 2023, Номер 28(8), С. 3355 - 3364

Опубликована: Авг. 1, 2023

Язык: Английский

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The Relationships between Effortful Control, Mind Wandering, and Mobile Phone Addiction Based on Network Analysis

Healthcare, Год журнала: 2024, Номер 12(2), С. 140 - 140

Опубликована: Янв. 8, 2024

Background: The prevailing mobile phone use brought the problem of addiction, which might cause negative consequences. Effortful control and mind wandering were associated with addictive behavior. present study aimed to investigate dimension-level relationships between effortful control, wandering, addiction. Methods: A total 1684 participants participated this study. measured through self-report scales, respectively. Dimension-level network these psychological variables was estimated bridge expected influence (BEI) values for each node calculated. Results: Dimensions exhibited distinct complex links other. “activation control” highest BEI value (BEI = −0.32), whereas “spontaneous thinking” showed positive 0.20). Conclusions: Different dimensions had varied yet significant connections facilitating understanding specific pathways underlying three constructs. identified dominant nodes can provide potential targets intervention

Язык: Английский

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Differential effects of high-definition transcranial direct current stimulation (HD-tDCS) on attentional guidance by working memory in males with substance use disorder according to memory modality

Brain and Cognition, Год журнала: 2024, Номер 177, С. 106149 - 106149

Опубликована: Апрель 4, 2024

Язык: Английский

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Medial prefrontal neuroplasticity during extended-release naltrexone treatment of opioid use disorder – a longitudinal structural magnetic resonance imaging study

Translational Psychiatry, Год журнала: 2024, Номер 14(1)

Опубликована: Сен. 5, 2024

Язык: Английский

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Table tennis experience enhances motor control in older adults: Insights into sensorimotor-related cortical connectivity

International Journal of Clinical and Health Psychology, Год журнала: 2024, Номер 24(2), С. 100464 - 100464

Опубликована: Апрель 1, 2024

Motor control declines with age and requires effective connectivity between the sensorimotor cortex primary motor (M1). Despite research indicating that physical exercise can improve in older individuals effect of on neural adults remains to be elucidated. Older experience table tennis fit aerobics without such for comparison were recruited study. Differences assessed using stop-signal task. The impact DLPFC-M1 pre-SMA-M1 was transcranial magnetic stimulation. Varied time intervals (short long term) stimulus intensities (subthreshold suprathreshold) used explore across pathways. present study showed behavioral iexpression group significantly better than other two groups;The facilitatory regulation preSMA-M1 all groups is negatively correlated SSRT. Regulatory efficiency highest group. Only network regulatory ability Table Tennis a negative correlation SSRT; Inhibitory positively this most robust preliminary findings suggest may enhance system regulated by networks stabilize inhibitory DLPFC-M1, thereby affecting adults.

Язык: Английский

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