Cross-sectional and longitudinal changes in category-selectivity in visual cortex following pediatric cortical resection

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Дек. 12, 2024

Abstract The topographic organization of category-selective responses in human ventral occipitotemporal cortex (VOTC) and its relationship to regions subserving language functions is remarkably uniform across individuals. This arrangement thought result from the clustering neurons responding similar inputs, constrained by intrinsic architecture tuned experience. We examined malleability this individuals with unilateral resection VOTC during childhood for management drug-resistant epilepsy. In cross-sectional longitudinal functional imaging studies, we compared topography neural representations 17 a resection, ‘control patient’ outside VOTC, typically developing matched controls. demonstrated both adherence deviation standard uncovered fine-grained competitive dynamics between word- face-selectivity over time single, preserved VOTC. findings elucidate nature extent cortical plasticity highlight potential remodeling extrastriate function. Teaser After pediatric deviations constraints visual reflect plasticity.

Язык: Английский

An intrinsic hierarchical, retinotopic organization of visual pulvinar connectivity in the human neonate

Current Biology, Год журнала: 2024, Номер unknown

Опубликована: Дек. 1, 2024

Язык: Английский