Journal of Neuroscience, Год журнала: 2024, Номер 44(48), С. e1367242024 - e1367242024
Опубликована: Ноя. 27, 2024
The nervous system contains complex circuits comprising thousands of cell types and trillions connections. Here, we discuss how the field “developmental systems neuroscience” combines molecular genetic perspectives developmental neuroscience with (typically adult-focused) functional perspective neuroscience. This combination approaches is critical to understanding a handful cells eventually produce wide range behaviors necessary for survival. Functional circuit development typically lags behind neural connectivity, leading intermediate stages activity that are either not seen in adults or, if present, considered pathophysiological. Developmental examines these activity, mapping out phases inflection points function understand behavior emerge across development. Beyond typical development, this approach provides invaluable insight into pathophysiology neurodevelopmental disorders by identifying when diverges between health disease. We argue will identify important periods reveal novel therapeutic windows treatment, set stage answer fundamental questions about brain
Язык: Английский
