Pre‐processing visual scenes for retinal prosthesis systems: A comprehensive review DOI
Heidi Ahmed Holiel, Sahar Fawzi, Walid Al‐Atabany

и другие.

Artificial Organs, Год журнала: 2024, Номер 48(11), С. 1223 - 1250

Опубликована: Июль 18, 2024

Retinal prostheses offer hope for individuals with degenerative retinal diseases by stimulating the remaining cells to partially restore their vision. This review delves into current advancements in prosthesis technology, a special emphasis on pivotal role that image processing and machine learning techniques play this evolution.

Язык: Английский

Vertebrate vision: New light on the enigmatic double cone DOI
Almut Kelber

Current Biology, Год журнала: 2025, Номер 35(10), С. R382 - R384

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

Localisation of cryptochrome 2 in the avian retina DOI Creative Commons
Angelika Einwich, Pranav Kumar Seth, Rabea Bartölke

и другие.

Journal of Comparative Physiology A, Год журнала: 2021, Номер 208(1), С. 69 - 81

Опубликована: Окт. 22, 2021

Abstract Cryptochromes are photolyase-related blue-light receptors acting as core components of the mammalian circadian clock in cell nuclei. One or more members cryptochrome protein family also assumed to play a role avian magnetoreception, but primary sensory molecule retina migratory birds that mediates light-dependent magnetic compass orientation has still not been identified. The mRNA 2 (Cry2) reported be located nuclei retina, Cry2 localisation yet demonstrated at level. Here, we provide evidence is photoreceptor inner segments, outer nuclear layer, layer and ganglion night-migratory European robins, homing pigeons domestic chickens. At subcellular level, find both cytoplasm nucleus cells residing these layers. This broad nucleic expression rather points for consistent with function transcription factor, analogous Cry2, speaks against an involvement magnetoreception.

Язык: Английский

Процитировано

19

Spectral inference reveals principal cone-integration rules of the zebrafish inner retina DOI Creative Commons
Philipp Bartel, Takeshi Yoshimatsu, Filip Janiak

и другие.

Current Biology, Год журнала: 2021, Номер 31(23), С. 5214 - 5226.e4

Опубликована: Окт. 16, 2021

Retinal bipolar cells integrate cone signals at dendritic and axonal sites. The route, involving amacrine cells, remains largely uncharted. However, because types differ in their spectral sensitivities, insights into cells' integration might be gained based on tunings. We therefore recorded vivo responses of cell presynaptic terminals larval zebrafish to widefield but spectrally resolved flashes light mapped the results onto four cones. This "spectral circuit mapping" allowed explaining ∼95% temporal variance a simple linear model, thereby revealing several notable rules inner retina. Bipolar were dominated by red-cone inputs, often alongside equal sign inputs from blue green In contrast, UV-cone uncorrelated with those remaining led new axis opponency where red-, green-, blue-cone "Off" circuits connect "natively-On" outermost fraction plexiform layer—much as how key color opponent are established mammals. Beyond this, despite substantial diversity that was not present cones, tunings surprisingly simple. They either approximately resembled both non-opponent motifs already cones or exhibited stereotyped broadband response. this way, only preserved efficient representations also diversified them set up total six dominant motifs, which included three axes opponency.

Язык: Английский

Процитировано

18

Immunohistochemical characterization of bipolar cells in four distantly related avian species DOI Creative Commons
Vaishnavi Balaji, Silke Haverkamp, Pranav Kumar Seth

и другие.

The Journal of Comparative Neurology, Год журнала: 2022, Номер 531(4), С. 561 - 581

Опубликована: Дек. 22, 2022

Abstract Visual (and probably also magnetic) signal processing starts at the first synapse, which photoreceptors contact different types of bipolar cells, thereby feeding information into channels. In chicken retina, 15 and 22 cell have been identified based on serial electron microscopy single‐cell transcriptomics, respectively. However, immunohistochemical markers for avian cells were only anecdotally described so far. Here, we systematically tested 12 antibodies their ability to label individual in bird retina compared eight most suitable across distantly related species, namely domestic chicken, pigeon, common buzzard, European robin, retinal regions. While two (GNB3 EGFR) labeled specifically ON addition other retina. Staining pattern four (CD15, PKCα, PKCβ, secretagogin) was species‐specific. Two (calbindin showed a expression central peripheral For found slightly more somata inner nuclear layer than OFF somata. contrast, made ribbon synapses plexiform these species. Finally, analyzed photoreceptor connectivity selected robin summary, provide catalog will greatly facilitate analyzing circuitry birds larger scale.

Язык: Английский

Процитировано

9

Pre‐processing visual scenes for retinal prosthesis systems: A comprehensive review DOI
Heidi Ahmed Holiel, Sahar Fawzi, Walid Al‐Atabany

и другие.

Artificial Organs, Год журнала: 2024, Номер 48(11), С. 1223 - 1250

Опубликована: Июль 18, 2024

Retinal prostheses offer hope for individuals with degenerative retinal diseases by stimulating the remaining cells to partially restore their vision. This review delves into current advancements in prosthesis technology, a special emphasis on pivotal role that image processing and machine learning techniques play this evolution.

Язык: Английский

Процитировано

1