bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 6, 2024
Abstract
The
human
brain
tracks
temporal
regularities
in
acoustic
signals
faithfully.
Recent
neuroimaging
studies
have
shown
complex
modulations
of
synchronized
neural
activities
to
the
shape
stimulus
envelopes.
How
connect
responses
different
envelope
shapes
with
listeners’
perceptual
ability
synchronize
rhythms
requires
further
characterization.
Here
we
examine
participants’
motor
and
sensory
synchronization
noise
stimuli
periodic
amplitude
(AM).
We
used
three
that
varied
sharpness
onset.
In
a
synchronous
finger-tapping
task,
show
participants
more
consistently
align
their
taps
same
phase
when
listening
sharp
onsets
than
those
gradual
onsets.
This
effect
is
replicated
suggesting
basis
for
facilitated
alignment
sharp-onset
stimuli.
Surprisingly,
despite
less
consistent
tap
alignments
gradual-onset
stimuli,
are
equally
effective
extracting
rate
modulation
from
both
they
tapped
at
alongside
input.
result
demonstrates
robust
tracking
periodicity
achievable
without
presence
edges
or
envelope.
Our
findings
assuming
distinct
processes
during
sensorimotor
synchronization.
These
may
be
underpinned
by
mechanisms
whose
relative
strengths
modulated
specific
dynamics
characteristics.
Hearing Research,
Год журнала:
2024,
Номер
443, С. 108967 - 108967
Опубликована: Янв. 30, 2024
Hearing
loss
affects
approximately
18%
of
the
population
worldwide.
difficulties
in
noisy
environments
without
accompanying
audiometric
threshold
shifts
likely
affect
an
even
larger
percentage
global
population.
One
potential
causes
hidden
hearing
is
cochlear
synaptopathy,
synapses
between
inner
hair
cells
(IHC)
and
auditory
nerve
fibers
(ANF).
These
are
most
vulnerable
structures
cochlea
to
noise
exposure
or
aging.
The
deafferentation,
i.e.,
afferent
information,
whose
downstream
effect
information
that
sent
higher-order
processing
stages.
Understanding
physiological
perceptual
effects
this
early
deafferentation
might
inform
interventions
prevent
later,
more
severe
loss.
In
past
decade,
a
large
body
work
has
been
devoted
better
understand
loss,
including
their
corresponding
impact
on
pathway,
use
measures
for
clinical
diagnosis
deafferentation.
This
review
synthesizes
findings
from
studies
humans
animals
answer
some
key
questions
field,
it
points
gaps
knowledge
warrant
investigation.
Specifically,
recent
suggest
electrophysiological
have
function
as
indicators
humans,
but
research
needed
these
be
included
part
test
battery.
Human Brain Mapping,
Год журнала:
2024,
Номер
45(1)
Опубликована: Янв. 1, 2024
Abstract
Healthy
aging
leads
to
complex
changes
in
the
functional
network
of
speech
processing
a
noisy
environment.
The
dual‐route
neural
architecture
has
been
applied
study
processing.
Although
evidence
suggests
that
senescent
increases
activity
brain
regions
across
dorsal
and
ventral
stream
offset
reduced
periphery,
regulatory
mechanism
networks
underlying
such
compensation
remains
largely
unknown.
Here,
by
utilizing
near‐infrared
spectroscopy
(fNIRS),
we
investigated
compensatory
connectivity,
its
relationship
with
healthy
using
perception
task
at
varying
signal‐to‐noise
ratios
(SNR)
individuals
(young
adults,
middle‐aged
older
adults).
Results
showed
scores
significant
age‐related
decrease
reduction
SNR.
analysis
results
connection
Wernicke's
area
homolog
were
increases.
Further
clarify
characteristics
networks,
graph‐theoretical
revealed
an
increase
efficiency
differences
nodal
found
both
under
noise
Thus,
might
be
key
hub
maintain
efficient
information
transfer
process
aging.
Moreover,
adults
would
recruit
more
resources
from
homologous
recruitment
provide
means
for
decoding
adverse
listening
Together,
our
characterized
environments
provided
new
insight
theories
how
modulates
networks.
Scientific Reports,
Год журнала:
2022,
Номер
12(1)
Опубликована: Апрель 7, 2022
Abstract
Fluctuating
background
sounds
facilitate
speech
intelligibility
by
providing
‘glimpses’
(masking
release).
Older
adults
benefit
less
from
glimpses,
but
masking
release
is
typically
investigated
using
isolated
sentences.
Recent
work
indicates
that
engaging,
continuous
materials
(e.g.,
spoken
stories)
may
qualitatively
alter
speech-in-noise
listening.
Moreover,
neural
sensitivity
to
different
amplitude
envelope
profiles
(ramped,
damped)
changes
with
age,
whether
this
affects
listening
unknown.
In
three
online
experiments,
we
investigate
how
in
younger
and
older
differs
for
masked
sentences
stories,
varies
masker
profile.
Intelligibility
was
generally
greater
damped
than
ramped
maskers.
Masking
reduced
relative
disconnected
sentences,
stories
a
randomized
sentence
order.
Critically,
when
an
engaging
coherent
narrative,
demonstrated
equal
or
compared
adults.
thus
appear
as
much
as,
more
than,
the
they
are
follows
topical
thread.
Our
results
highlight
importance
of
cognitive
motivational
factors
understanding,
suggest
previous
have
underestimated
speech-listening
abilities
Journal of Neurophysiology,
Год журнала:
2023,
Номер
129(6), С. 1359 - 1377
Опубликована: Апрель 25, 2023
We
observed
age-related
changes
in
cortical
temporal
processing
of
continuous
speech
that
may
be
related
to
older
adults’
difficulty
understanding
noise.
These
occur
both
timing
and
strength
the
representations
at
different
stages
depend
on
noise
condition
selective
attention.
Critically,
their
dependence
dramatically
among
early,
middle,
late
stages,
underscoring
how
aging
differentially
affects
these
stages.
The Journal of the Acoustical Society of America,
Год журнала:
2023,
Номер
153(4), С. 2298 - 2298
Опубликована: Апрель 1, 2023
The
perception
of
amplitude
modulations
(AMs)
has
been
characterized
by
a
frequency-selective
process
in
the
temporal
envelope
domain
and
simulated
computational
auditory
processing
models
using
modulation
filterbank.
Such
AM
argued
to
be
critical
for
complex
sounds,
including
speech.
This
study
aimed
at
investigating
effects
age
on
behavioral
frequency
selectivity
young
(n
=
11,
22–29
years)
versus
older
10,
57–77
listeners
with
normal
hearing,
simultaneous
masking
paradigm
sinusoidal
carrier
(2.8
kHz),
target
frequencies
4,
16,
64,
128
Hz,
narrowband-noise
maskers.
A
reduction
factor
up
2
was
found
listeners.
While
observed
co-varied
unmasked
detection
sensitivity,
age-related
broadening
masked
threshold
patterns
remained
stable
even
when
sensitivity
similar
across
groups
an
extended
stimulus
duration.
results
from
present
might
provide
valuable
basis
further
investigations
exploring
reduced
sound
as
well
interaction
hearing
impairment
perception.
