Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association

Circulation, Год журнала: 2023, Номер 147(8)

Опубликована: Янв. 25, 2023

Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs). Methods: through its Epidemiology Prevention Statistics Committee, continuously monitors evaluates sources stroke United States provide current information available annual review published literature year before writing. 2023 is product full year’s worth effort 2022 by dedicated volunteer clinicians scientists, committed government professionals, Association staff members. strives further understand help heal problems inflicted structural racism, public crisis can significantly damage mental perpetuate disparities access education, income, housing, several other vital healthy lives. This edition includes additional COVID-19 (coronavirus 2019) publications, as well monitoring benefits population, an enhanced focus equity across key domains. Results: Each chapters focuses different topic statistics. Conclusions: represents critical resource for lay public, policymakers, media clinicians, care administrators, researchers, advocates, others seeking best these conditions.

Язык: Английский

---

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Circulation, Год журнала: 2022, Номер 145(8)

Опубликована: Янв. 26, 2022

The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs).

Язык: Английский

---

Update: Characteristics of Symptomatic Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status — United States, January 22–October 3, 2020

MMWR Morbidity and Mortality Weekly Report, Год журнала: 2020, Номер 69(44), С. 1641 - 1647

Опубликована: Ноя. 2, 2020

Studies suggest that pregnant women might be at increased risk for severe illness associated with coronavirus disease 2019 (COVID-19) (1,2). This report provides updated information about symptomatic of reproductive age (15-44 years) laboratory-confirmed infection SARS-CoV-2, the virus causes COVID-19. During January 22-October 3, CDC received reports through national COVID-19 case surveillance or National Notifiable Diseases Surveillance System (NNDSS) 1,300,938 aged 15-44 years laboratory results indicative acute SARS-CoV-2. Data on pregnancy status were available 461,825 (35.5%) infection, 409,462 (88.7%) whom symptomatic. Among women, 23,434 (5.7%) reported to pregnant. After adjusting age, race/ethnicity, and underlying medical conditions, significantly more likely than nonpregnant admitted an intensive care unit (ICU) (10.5 versus 3.9 per 1,000 cases; adjusted ratio [aRR] = 3.0; 95% confidence interval [CI] 2.6-3.4), receive invasive ventilation (2.9 1.1 aRR 2.9; CI 2.2-3.8), extracorporeal membrane oxygenation (ECMO) (0.7 0.3 2.4; 1.5-4.0), die (1.5 1.2 1.7; 1.2-2.4). Stratifying these analyses by race/ethnicity highlighted disparities in subgroup. Although absolute risks outcomes low, COVID-19-associated illness. To reduce death from COVID-19, should counseled importance seeking prompt if they have symptoms measures prevent SARS-CoV-2 strongly emphasized their families during all encounters, including prenatal visits. Understanding among is important prevention counseling clinical treatment.

Язык: Английский

---

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation, Год журнала: 2024, Номер 149(8)

Опубликована: Янв. 24, 2024

BACKGROUND: The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep, obesity) factors (cholesterol, blood pressure, glucose control, metabolic syndrome) that contribute health. AHA Disease Stroke Statistical Update presents latest data on a range major clinical circulatory disease conditions (including brain health, complications pregnancy, kidney congenital rhythm disorders, sudden cardiac arrest, subclinical atherosclerosis, coronary cardiomyopathy, failure, valvular venous thromboembolism, peripheral artery disease) associated outcomes quality care, procedures, economic costs). METHODS: AHA, through its Epidemiology Prevention Statistics Committee, continuously monitors evaluates sources stroke United States globally provide current information available annual review published literature year before writing. 2024 is product full year’s worth effort 2023 by dedicated volunteer clinicians scientists, committed government professionals, staff members. strives further understand help heal problems inflicted structural racism, public crisis can significantly damage mental perpetuate disparities access education, income, housing, several other vital healthy lives. This edition includes additional global data, as well monitoring benefits population, an enhanced focus equity across key domains. RESULTS: Each chapters focuses different topic statistics. CONCLUSIONS: represents critical resource for lay public, policymakers, media clinicians, care administrators, researchers, advocates, others seeking best these conditions.

Язык: Английский

---

The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis

Canadian Medical Association Journal, Год журнала: 2021, Номер 193(16), С. E540 - E548

Опубликована: Март 19, 2021

The impact of coronavirus disease 2019 (COVID-19) on maternal and newborn health is unclear. We aimed to evaluate the association between severe acute respiratory syndrome 2 (SARS-CoV-2) infection during pregnancy adverse outcomes.We conducted a systematic review meta-analysis observational studies with comparison data SARS-CoV-2 severity COVID-19 pregnancy. searched for eligible in MEDLINE, Embase, ClinicalTrials.gov, medRxiv Cochrane databases up Jan. 29, 2021, using Medical Subject Headings terms keywords "severe OR COVID-19" AND "pregnancy." evaluated methodologic quality all included Newcastle-Ottawa Scale. Our primary outcomes were preeclampsia preterm birth. Secondary stillbirth, gestational diabetes other outcomes. calculated summary odds ratios (ORs) or weighted mean differences 95% confidence intervals (CI) random-effects meta-analysis.We 42 involving 438 548 people who pregnant. Compared no pregnancy, was associated (OR 1.33, CI 1.03 1.73), birth 1.82, 1.38 2.39) stillbirth 2.11, 1.14 3.90). mild COVID-19, strongly 4.16, 1.55 11.15), 4.29, 2.41 7.63), 1.99, 1.09 3.64) low weight 1.89, 3.12).COVID-19 may be increased risks preeclampsia,

Язык: Английский

---

Disease severity, pregnancy outcomes, and maternal deaths among pregnant patients with severe acute respiratory syndrome coronavirus 2 infection in Washington State

American Journal of Obstetrics and Gynecology, Год журнала: 2021, Номер 225(1), С. 77.e1 - 77.e14

Опубликована: Янв. 27, 2021

Язык: Английский

---

The safety of Covid-19 mRNA vaccines: a review

Patient Safety in Surgery, Год журнала: 2021, Номер 15(1)

Опубликована: Май 1, 2021

Abstract The novel coronavirus disease 2019 (COVID-19) has infected more than 100 million people globally within the first year of pandemic. With a death toll surpassing 500,000 in United States alone, containing pandemic is predicated on achieving herd immunity global scale. This implies that at least 70-80 % population must achieve active against severe acute respiratory syndrome 2 (SARS-CoV-2), either as result previous COVID-19 infection or by vaccination SARS-CoV-2. In December 2020, two vaccines were approved FDA through emergency use authorization States. These are based mRNA vaccine platform and developed Pfizer/BioNTech Moderna. Published safety efficacy trials reported high rates 94-95 after interval doses, conjunction with limited side effects low rate adverse reactions. rapid pace development uncertainty potential long-term raised some level hesitation community. A successful campaign contingent widespread access to under appropriate storage conditions, deployment sufficient number vaccinators, willingness be vaccinated. Thus, it important clarify objective data related safety, including known present review was designed provide an update current state science SARS-CoV-2 vaccines.

Язык: Английский

---

Neurodevelopmental Outcomes at 1 Year in Infants of Mothers Who Tested Positive for SARS-CoV-2 During Pregnancy

JAMA Network Open, Год журнала: 2022, Номер 5(6), С. e2215787 - e2215787

Опубликована: Июнь 9, 2022

Importance

Epidemiologic studies suggest maternal immune activation during pregnancy may be associated with neurodevelopmental effects in offspring.

Objective

To evaluate whether utero exposure to SARS-CoV-2 is risk for disorders the first 12 months after birth.

Design, Setting, and Participants

This retrospective cohort study examined live offspring of all mothers who delivered between March September 2020 at any 6 Massachusetts hospitals across 2 health systems. Statistical analysis was performed from October December 2021.

Exposures

Maternal infection confirmed by a polymerase chain reaction test pregnancy.

Main Outcomes Measures

Neurodevelopmental determined fromInternational Classification Diseases Related Health Problems, Tenth Revision (ICD-10)diagnostic codes over life; sociodemographic clinical features offspring; drawn electronic record.

Results

The included 7772 births (7466 pregnancies, 96% singleton, 222 positive mothers), mean (SD) age 32.9 (5.0) years; were 9.9% Asian (772), 8.4% Black (656), 69.0% White (5363); 15.1% (1134) Hispanic ethnicity. Preterm delivery more likely among exposed mothers: 14.4% (32) vs 8.7% (654) (P = .003). positivity greater rate diagnoses unadjusted models (odds ratio [OR], 2.17 [95% CI, 1.24-3.79];P .006) as well those adjusted race, ethnicity, insurance status, sex, age, preterm status (adjusted OR, 1.86 1.03-3.36];P .04). Third-trimester larger magnitude 2.34 1.23-4.44];P .01).

Conclusions Relevance

found preliminary evidence that sequelae some Prospective longer follow-up duration will required exclude confounding confirm these associations.

Язык: Английский

---

Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2

Nature Communications, Год журнала: 2022, Номер 13(1)

Опубликована: Янв. 18, 2022

Pregnant women represent a high-risk population for severe/critical COVID-19 and mortality. However, the maternal-fetal immune responses initiated by SARS-CoV-2 infection, whether this virus is detectable in placenta, are still under investigation. Here we show that infection during pregnancy primarily induces unique inflammatory at interface, which largely governed maternal T cells fetal stromal cells. also associated with humoral cellular blood, as well mild cytokine response neonatal circulation (i.e., umbilical cord blood), without compromising T-cell repertoire or initiating IgM responses. Importantly, not detected placental tissues, nor sterility of placenta compromised viral infection. This study provides insight into triggered emphasizes rarity

Язык: Английский

---

COVID-19 Vaccination Coverage Among Pregnant Women During Pregnancy — Eight Integrated Health Care Organizations, United States, December 14, 2020–May 8, 2021

MMWR Morbidity and Mortality Weekly Report, Год журнала: 2021, Номер 70(24), С. 895 - 899

Опубликована: Июнь 15, 2021

COVID-19 vaccines are critical for ending the pandemic; however, current data about vaccination coverage and safety in pregnant women limited. Pregnant at increased risk severe illness death from compared with nonpregnant of reproductive age, adverse pregnancy outcomes, such as preterm birth (1-4). eligible can receive any three available United States via Emergency Use Authorization.* Data Vaccine Safety Datalink (VSD), a collaboration between CDC multiple integrated health systems, were analyzed to assess receipt ≥1 dose (first or second Pfizer-BioNTech Moderna single Janssen [Johnson & Johnson] vaccine) vaccine during pregnancy, first 2-dose (initiation), completion 1- series. During December 14, 2020-May 8, 2021, total 135,968 identified, 22,197 (16.3%) whom had received pregnancy. Among these women, 7,154 (5.3%) initiated 15,043 (11.1%) completed Receipt was highest among aged 35-49 years (22.7%) lowest those 18-24 (5.5%), higher non-Hispanic Asian (Asian) (24.7%) White (White) (19.7%) than Hispanic (11.9%) Black (Black) (6.0%). Vaccination all racial ethnic groups over analytic period, likely because eligibility vaccination† availability time. These findings indicate need improved outreach engagement especially minority who might be outcomes (4). In addition, providing accurate timely information care providers, age improve confidence by ensuring optimal shared clinical decision-making.

Язык: Английский

---