Russian Cardiology Bulletin, Год журнала: 2024, Номер 19(4), С. 72 - 72
Опубликована: Янв. 1, 2024
Язык: Английский
Kardiologiia, Год журнала: 2025, Номер 65(2), С. 69 - 76
Опубликована: Фев. 28, 2025
Currently, the diagnosis of amyloid cardiomyopathy (ACM) causes great difficulties both for practicing primary care physicians and specialists. One reasons is variety symptoms in patients with ACM. The most common ACM manifestations include heart failure preserved left ventricular ejection fraction, hypertrophic phenotype cardiomyopathy, thromboembolic complications, valvular apparatus damage. Common are mitral tricuspid valve insufficiency aortic stenosis (AS). Diagnosis particularly difficult AS requiring differentiation between as a degenerative defect origin. According to literature, 4-16% cases older (≥65 years), genesis precisely
Язык: Английский
Процитировано
0
South Russian Journal of Therapeutic Practice, Год журнала: 2025, Номер 6(1), С. 27 - 37
Опубликована: Март 30, 2025
Objective: to study the characteristics of cardiorenal relationships in patients with coronary heart disease (CHD) who have suffered a myocardial infarction combination CKD. Materilas and methods: included 110 had acute (AMI) grade 1–2 hypertension, also CKD stages 1-3. The clinical clarification functional class CHF using 6-minute walk test (TSH), assessment severity on SHOKS scale, electrocardiography (ECG), echocardiography (ECHOCG), daily blood pressure monitoring (SMAD), Holter ECG monitoring. state kidneys was assessed by level glomerular filtration rate (GFR) (formula CKD-EPI), ratio albumin creatinine urine (AU), as well N-acetyl-β-D-glucosaminidase (NAG) urine. Results: exceeding reference NAG values demonstrated close association damage epithelium proximal tubules. In studied group, number more than 3.16 ng/ml 96 (87.3%). It shown that levels AU are closely related (r = 0.86, p 0.001). When analyzing TSH, it found value TSH decreased, increased 0.34, < 0.05). an increase SHOCK score associated decrease GFR -0.44, There no significant correlation between this parameter As left dilates, systolic function decreases hypertrophy progresses, there is statistically GFR. were higher subgroup concentric hypertrophy. During analysis interrelationships SMAD indicators parameters reflecting renal tissue, average SAD noted An variability SAD, index hypertension time morning rise. Changes fewer connections SMAD. results monitoring, decreases, probability detecting cases ischemia (SIM) increases, duration all episodes ischemia. concentration likelihood SIM, pain-free (BBIM). Conclusions: tubular lesions form urine, capacity (decrease GFR) processes remodeling disease, PIC equally, however, high pathological profiles presence At same , occurrence pain–free lesions.
Язык: Английский
Процитировано
0
Kardiologiia, Год журнала: 2025, Номер 65(3), С. 35 - 47
Опубликована: Март 31, 2025
Ischemic heart disease, including previous myocardial infarction (MI), is one of the main causes for development and progression failure (HF). The presence HF before MI or in setting acute coronary catastrophe an extremely unfavorable prognostic factor leading to a multiple increase risk death rehospitalization due post-infarction period. In 2024, results two randomized clinical trials (RCTs) (DAPA-MI EMPACT-MI) were published, which assessed effect sodium-glucose co-transporter type 2 inhibitors (SGLT2i) on outcomes patients with MI. both studies, predetermined primary composite endpoint was not achieved. At same time, it shown that SGLT2i significantly reduced hospitalization (empagliflozin) contributed improvement metabolic (dapagliflozin). Also, safety early initiation period demonstrated. Based available observational working group has substantiated need implementing these RCT into practice proposed algorithm administering SGLT2 Thus, compelling anamnestic criteria diagnosis previously diagnosed diabetes mellitus, and/or chronic kidney HF, continuation timely during index recommended improve cardiovascular renal outcomes. RCTs taking account individual factors discharge may be considered order reduce HF.
Язык: Английский
Процитировано
0
Rational Pharmacotherapy in Cardiology, Год журнала: 2025, Номер 21(1), С. 14 - 21
Опубликована: Фев. 9, 2025
Aim. To find out physicians’ knowledge and perceptions about the possibilities of using therapy affecting prognosis in patients with chronic heart failure reduced ejection fraction (CHFrEF). Material methods. Data an anonymous survey 207 physicians (155 cardiologists, 44 internists, 8 other specialists) who past advanced course professional training spring 2023. Questionnaire contained questions reflecting awareness treatment for improving CHFrEF. Results. The quadruple therapy: sacubitril- valsartan (ARNI)/angiotensin- converting enzyme inhibitor /angiotensin II receptor blocker + beta-blocker (BB) mineralocorticoid antagonist (MRA) sodium- glucose cotransporter type 2 (SGLT2i) was named as optimal CHFrEF by 63.3 % doctors (71.6 cardiologists 36.4 internists). 80 respondents (89 50 internists) correctly pointed indications ARNI, 75.4 (83.9 45.4 — BB, 71.0 (80 36.3 prescribing AMR, 76.8 (86.4 43.1 SGLT2i. 81.7 (89.7 52.3 target dose 45.9 (51 31.8 indicated neuromodulatory 74.3 noted recommended dapagliflozin (p < 0,01 all comparisons between groups Among drugs that are most often used everyday practice to improve symptomatic CHFrEF, BB (66.2 %), MRA (58.5 angiotensin- inhibitor/angiotensin (57 ARNI (37.7 SGLT2i (45.4 %). Cardiologists use 0,01), 0,05) more than internists. Conclusion. Insufficient physicians, especially key provisions clinical guidelines pharmacotherapy can be considered one reasons suboptimal treatment.
Язык: Английский
Процитировано
0
Russian Journal of Cardiology, Год журнала: 2024, Номер 29(6), С. 5940 - 5940
Опубликована: Май 12, 2024
Aim. To assess total, ageand sex-specific survival rate after discharge of patients with heart failure (HF) using real-world electronic health data. Material and methods. This retrospective analysis data from the St. Petersburg Chronic Heart Failure Registry was performed. Hospitalizations aged 18 years a diagnosis code I50.x (International Classification Diseases, 10 th revision) were included in period January 1, 2019 to December 31, 2023. Cases acute myocardial infarction, cerebrovascular accident, coronavirus disease 2019, hospitalization duration >30 days, death during current not included. Results. The study 73450 99 (mean age, 73±12 years; women, 59,1%). During median follow-up 388 16212 (22,1%) died. cumulative probability within one five 16,3% 48,9%. At each time period, higher men when stratified by age as increased. mortality 15,3 (95% confidence interval 15,1 15,6) per 100 patientyears. For all subgroups, highest value recorded first month (50,1 patient-years), reaching maximum subgroup elderly senile (60,7 patient-years). Conclusion. Within 1 year 5 hospital discharge, 48,9% HF die, respectively. risk is typical especially for patients.
Язык: Английский
Процитировано
2
Kardiologiia, Год журнала: 2024, Номер 64(8), С. 68 - 78
Опубликована: Авг. 31, 2024
The burden of heart failure (HF) has been increasing worldwide in recent decades. Early diagnosis HF based on the outpatient measurement natriuretic peptide (NP) concentration will allow timely initiation treatment and reducing incidence adverse outcomes HF. Unfortunately, frequency NP testing remains low worldwide. At online expert meeting held March 15, 2024, features N-terminal pro-brain (NT-proBNP) test (Elecsys proBNP by Roche) were discussed along with interpretation results presentation laboratory reports. experts addressed Elecsys patients suspected various clinical scenarios (chronic acute HF). limits decision for NT-proBNP established depending scenario. Changes comorbidities addressed. suggested ways to optimize format result reports Russian Federation, which accelerate implementation practice management patients.
Язык: Английский
Процитировано
1
Russian Journal of Cardiology, Год журнала: 2024, Номер 29(9), С. 5854 - 5854
Опубликована: Июнь 10, 2024
Heart failure (CHF) is a syndrome characterized by progressive course with varying duration of stability period, frequent episodes clinical deterioration, despite the therapy. HF deterioration often leads to repitalizations and poor prognosis. A possible reduction in rehospitalization rate prognosis improvement early administration optimal therapy modernization non-drug approaches an urgent area research. An integrated approach using scales, algorithms relevant strategies can significantly improve treatment outcomes quality life patients HF.
Язык: Английский
Процитировано
1
Terapevticheskii arkhiv, Год журнала: 2024, Номер 96(7), С. 666 - 674
Опубликована: Июль 30, 2024
To evaluate the impact of a decrease in glomerular filtration rate (GFR) on prognosis patients with chronic heart failure (CHF), to analyze real clinical practice regarding frequency prescribing pathogenetic therapy for CHF, achieving target dosages depending gradation GFR included CHF Register Tyumen region.
Язык: Английский
Процитировано
0
Terapevticheskii arkhiv, Год журнала: 2024, Номер 96(8), С. 771 - 779
Опубликована: Сен. 14, 2024
To evaluate the clinical and economic effectiveness of dapagliflozin in patients with chronic heart failure (CHF) reduced left ventricular ejection fraction (HFrEF) Russian Federation various subgroups standard therapy for CHF.
Язык: Английский
Процитировано
0
CARDIOVASCULAR THERAPY AND PREVENTION, Год журнала: 2024, Номер 23(8), С. 4006 - 4006
Опубликована: Сен. 11, 2024
The prevalence of heart failure with preserved ejection fraction (HFpEF) is relentlessly increasing, especially in women. Therefore, an important task search for novel markers and early predictors the disease. Evaluation association between physiological factors complications pregnancy development both longterm (HF) also a substantial question. younger women cohort particular interest because high HFpEF among Russia. purpose review to assess gender differences HF, as well summarize results studies on adverse outcomes HFpEF. article describes characteristics various HF types. We considered morphofunctional, neurohumoral age associated women, influence leading risk men Particular attention paid role following variants have been identified: (peripartum) late (diagnosed postmenopause). pathophysiological mechanisms impact extragenital are described separately. studying relationship long-term prognosis, most characteristic form postmenopause hypertensive disorders (including preeclampsia eclampsia) gestational diabetes mellitus. A wider study woman’s future necessary identify new its development.
Язык: Английский
Процитировано
0