The ejection fraction and the cardiac index in the perioperative period of coronary artery bypass grafting: what is worth relying on?
Almanac of Clinical Medicine,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 15, 2025
Rationale:
Ejection
fraction
(EF)
has
been
recognized
as
a
key
echocardiographic
parameter
describing
the
systolic
function
of
heart.
Nevertheless,
its
accuracy
for
assessment
hemodynamic
status
in
perioperative
period
cardiac
surgery
remains
debate.
Aim:
To
compare
EF
values
assessed
by
different
techniques
and
to
map
those
against
left
ventricular
parameters
off-pump
coronary
artery
bypass
grafting
(OPCABG).
Methods:
We
performed
post
hoc
analysis
two
consequential
randomized
studies.
was
with
echocardiography
115
patients
OPCABG
changes
over
time
at
following
timepoints:
before
admission
hospital
(EFscreening),
on
day
(EFsimpson)
(transthoracic
approach),
sternotomy,
end
(transesophageal
echocardiography,
TEE),
well
first
postoperative
(POD1)
discharge
from
approach).
Preoperatively
POD1,
were
compared
global
longitudinal
strain
(GLS)
measured
automatically
(EFauto,
QLAB
10.0),
thermodilution
(TD),
such
index
(CI)
stroke
volume
(SVI).
Results:
There
no
EFscreening
EFsimpson
values.
EFauto
decreased
48.4
±
6.4
41.6
7.3%
(p
0.001),
while
EFtee
increased
49.7
[46.0;
57.0]
53.0
[46.1;
58.1]%
=
0.047)
associated
decrease
GLS
-14.6
2.5
-11.7
2.6%
0.001).
The
bias
measurement
POD1
according
Bland-Altman
test
29.3%
34.0%.
correlation
between
preoperatively
(rho
-0.791,
p
0.001)
-0.723,
did
not
show
correlation.
or
CI,
well.
SVItd
SVIecho
11%
0.301,
Conclusion:
does
characterize
heart
reliably
depends
method
measurement.
These
limitations
require
their
critical
evaluation,
including
comparison
variables.
Язык: Английский
Heat shock proteins as potential biomarkers of heart failure
CARDIOVASCULAR THERAPY AND PREVENTION,
Год журнала:
2024,
Номер
23(4), С. 3938 - 3938
Опубликована: Апрель 13, 2024
The
number
of
patients
with
heart
failure
(HF)
has
increased
markedly
over
the
past
decades
and
continues
to
increase.
During
pathological
cardiac
remodeling
in
HF,
vicious
cycles
cellular
stress
are
triggered.
This
review
is
devoted
a
group
heat
shock
proteins
(HSPs)
stimulated
by
stress,
which
make
it
possible
consider
them
as
potential
cardiovascular
biomarkers,
including
for
HF.
presents
features
most
studied
low-molecular-weight
high-molecular-weight
HSPs,
can
complement
range
non-invasive
laboratory
diagnostics
clinical
data
required
when
making
diagnosis.
will
also
help
assessing
prognosis
choosing
therapeutic
strategy
aimed
at
improving
patient's
quality
life
reducing
events
aim
analyze
publications
on
biochemical
studies
HSPs
diagnostic
markers
HF
patients.
Язык: Английский
Associations of cartilage intermediate layer protein 1 and hypoxia-inducible factor-1-alpha with transthoracic echocardiography results in patients with heart failure with preserved ejection fraction
Russian Journal of Cardiology,
Год журнала:
2024,
Номер
29(6), С. 5908 - 5908
Опубликована: Апрель 20, 2024
Aim.
To
evaluate
the
relationship
of
serum
concentrations
myocardial
remodeling
and
cellular
hypoxia
biomarkers
cartilage
intermediate
layer
protein
1
(CILP-1)
hypoxia-inducible
factor-1-alpha
(HIF-1α)
with
paraclinical
parameters
in
patients
heart
failure
preserved
ejection
fraction
(HFpEF)
control
group.
Material
methods.
The
study
included
47
diagnosed
HFpEF,
aged
from
to
79
years,
who
were
treated
May
2018
December
2019
hospital
National
Medical
Research
Center
for
Therapy
Preventive
Medicine.
group
consisted
32
people
without
a
diagnosis
matched
by
sex
age.
All
participants
underwent
transthoracic
echocardiography
assessment
diastolic
function.
Serum
CILP-1
HIF-1α
determined
enzyme
immunoassay
using
standardized
test
systems
(RayBio
Clone-Cloud,
USA).
Results.
In
median
(3,24
ng/ml)
(14,3
pg/ml)
not
significantly
different
values
obtained
(3,6
ng/ml
7,5
pg/ml,
respectively).
Significant
correlations
echocardiographic
indicators
left
ventricular
interstitial
fibrosis
severity
revealed,
while
markers
HFpEF
positively
correlated
level.
Conclusion.
Although
do
differ
depending
on
presence,
it
demonstrates
an
association
number
both
subgroups
controls
body
mass
index.
Язык: Английский
Comparative assessment of venous congestion severity and hospitalization outcomes in patients with acute decompensated heart failure with preserved ejection fraction
Russian Journal of Cardiology,
Год журнала:
2024,
Номер
29(7), С. 5977 - 5977
Опубликована: Авг. 27, 2024
Aim.
To
characterize
the
potental
of
additional
paraclinical
research
methods
(ultrasound,
determination
body
composition)
for
assessing
congestion
severity
in
patients
with
acute
decompensated
heart
failure
preserved
ejection
fraction
(ADHFpEF)
intensive
care
unit.
Material
and
.
We
examined
82
ADHFpEF
aged
from
50
to
85
years,
who
were
hospitalized
unit
Veresaev
City
Clinical
Hospital
(Moscow).
All
underwent
a
standard
clinical
laboratory
examination,
including
NT-proBNP,
as
well
echocardiography,
chest
radiography,
bioimpedance
analysis,
Venous
Excess
Ultrasound
(VExUS),
lung
ultrasound.
Depending
on
degree
visualized
by
VExUS,
divided
into
three
groups.
Results.
The
median
levels
E/A
E/e',
number
B-lines
one
segment,
ECW
TBW,
diuretics'
dose
used
hospital
pa
tients
severe
significantly
higher.
Signs
obtained
result
X-ray
examination
did
not
differ
between
In-hospital
death
was
associated
higher
values
ratio,
IVC
diameter,
TBW.
odds
VExUS
Grade
3
increased
20,9
times
compared
1
(95%
CI:
1,125-387,688).
Conclusion.
Higher
diuretics
hospital,
TBW
severity.
assessed
ECW/TBW
are
positively
inhospital
mortality
Язык: Английский
Markers of heart failure with preserved ejection fraction in patients with unexplained dyspnea
CARDIOVASCULAR THERAPY AND PREVENTION,
Год журнала:
2023,
Номер
22(10), С. 3769 - 3769
Опубликована: Ноя. 29, 2023
Aim.
To
evaluate
the
prevalence
of
clinical,
history,
laboratory
and
ultrasound
markers
heart
failure
with
preserved
ejection
fraction
(HFpEF)
in
patients
unexplained
dyspnea,
as
well
to
identify
structural
myocardial
remodeling
this
group
patients.Material
methods.
This
retrospective
study
included
504
aged
18
84
years
who
were
hospitalized
from
July
1,
2022
March
31,
2023.
Patients
divided
into
two
groups
depending
on
presence
dyspnea.
A
comparative
analysis
parameters
was
carried
out
order
remodeling.Results.
number
associated
conditions
metabolic
disorders,
which
are
known
be
risk
factors
for
HFpEF,
detected
more
often
dyspnea
remodeling.
model
determine
probability
developed.
Two
most
significant
indicators
diabetes.Conclusion.
demonstrated
relationship
between
Identification
certain
clinical
morphological
signs
HFpEF
such
requires
apprehensive
attitude
in-depth
examination
rule
it.
Язык: Английский