Epidemiological Features of Obesity and Type 2 Diabetes Mellitus in the Russian Federation

Epidemiology and Vaccinal Prevention, Год журнала: 2024, Номер 23(4), С. 71 - 86

Опубликована: Сен. 6, 2024

Relevance. Obesity is associated with the risk of developing insulin resistance and type 2 diabetes mellitus (type DM). Over past 40 years, no country in world has seen a decrease incidence either obesity or diabetes. The epidemic growth rates DM world, including Russian Federation, emphasize close relationship these endocrinopathies identify as one determinants development. Aim. To study intensity, dynamics features formation primary morbidity among various population groups, well to correlations between studied parameters groups. Materials methods . A retrospective analysis Russia 2010–2021 was carried out. source analyzed information statistical collections Ministry Health Federation «Morbidity population». parameters, correlation performed calculation Pearson coefficient (r). interpretation closeness on Chaddock scale. Results. number cases amounted 4 428 975, – 3 839 772 2010–2021. entire 253,61 per 100 ths, 220,47 ths population. Siberian FD (377,29 ths) should be singled out an epidemiologically significant district, for Southern (249,34 ths). adults 274,22 while leading positions were taken by Ural (313,56 (308,94 In terms adults, it noted that 359,21 (the excess rate 1,68 times). Among elderly, 1,15 times higher than (247,15 ths), 1,23 (440,9 elderly group, maximum 591,11 ths. children from 0 14 years 370,99 most unfavorable situation North-Western (476,86 exceeding level 1,29 15 17, 697,67 (869,1 (866,43 parallel, also (3,16 teenagers 15–17 old. Positive established 2020 (r = 0,364 weak level) 2021 0,260 very level). Conclusion. association development been confirmed. Russia, parallel obesity, there increase DM. Special attention paid child population, since pronounced trend towards 0–14 old increasing teenagers. statistically obtained

Язык: Английский

Postprandial glycemic response to isocaloric carbohydrate load in men with different types of obesity

Obesity and metabolism, Год журнала: 2024, Номер 21(4), С. 348 - 356

Опубликована: Июнь 17, 2024

BACKGROUND : Carbohydrates exert major impact on postprandial blood glucose levels. Diet therapy for obesity and diabetes mellitus usually implies dietary restrictions the amount, type daily distribution of carbohydrates, wherein timing meals its composition play a significant role. However currently there is insufficient evidence-based data to guide how carbohydrates consumption should be distributed during day in obese men. AIM: To investigate levels response an isocaloric carbohydrate load at main (breakfast, lunch, dinner) individuals with different types obesity.MATERIALS AND METHODS: The study enrolled men aged 25 65 years. total number participants was 43 Group 1 (n=17) consisted subcutaneous fat (SFD) while group 2 (n=16) represented by abdominal (AFD). 3 (comparators) 10 normal body weight (NBW). duration continuous monitoring 5–6 days. Observation period included days usual physical work activity regimens. Glycemic assessed mealtime. During first fifth were instructed eat as without any restrictions. Standard breakfast introduced second standard lunch dinner performed third fourth respectively. RESULTS: Results representing showed that NBW most intense utilization occurs morning breakfast. Glucose tolerance significantly lower all AFD comparing SFD. In SFD relatively than only At time disposition glycemic curve didn’t differ. CONCLUSION: Dividing according phenotypes allows identify features regulation metabolism result reveal risk its’ complications. combination control can increase effectiveness therapeutic interventions offers pathogenetic approach personalized diet

Язык: Английский