The impact of sugar diet on humidity preference, survival, and host landing in mosquitoes

Journal of Medical Entomology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 13, 2025

Mosquito-borne diseases have caused more than 1 million deaths each year. There is an urgent need to develop effective way reduce mosquito-host interaction mitigate disease transmission. Sugar diets long been linked abnormal physiology in animals, making them potential candidates for mosquito control. Here, we show the impact of sugar on humidity preference and survival Aedes aegypti (Gainesville) Culex pipiens (Buckeye). Two-choice assays with high low relative (80% 50% RH) that species-specific. In comparison Cx. pipiens, various resulted marked reductions avidity Ae. aegypti, which exhibited significant differences. Among diets, arabinose significantly reduced rate mosquitoes at concentrations. Moreover, found host landing was not impacted by feeding different types. Our study suggests specific treatments could be applied control dampening their reducing lifespan, thus mosquito-borne

Язык: Английский

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Non-nutritive sugar feeding alters the genetic profile of diuretic hormones and their receptors in Drosophila suzukii (Diptera: Drosophilidae)

Annals of the Entomological Society of America, Год журнала: 2025, Номер unknown

Опубликована: Май 8, 2025

Abstract Non-nutritive sugars such as erythritol and sucralose are active ingredients in artificial sweeteners. In the past decade, research has demonstrated insecticidal properties of non-nutritive across several arthropod species. It is now a prospective chemical control option for spotted-wing drosophila, Drosophila suzukii, one most economically important pests small fruits. D. suzukii die quicker, excrete waste large amounts, become desiccated when fed mixture sucralose. The toxicity to fly not clearly elucidated but likely due nutritional physiological failures associated with an excess fluid excretion water imbalance, caused hyperosmotic body. diuretic processes insects primarily regulated by 3 neuropeptides: CAPA hormone, hormone 31 (DH31), 44 (DH44). To explore genetic effects on we investigated regulation key genes—capa, dh31, dh44—and their 7 corresponding receptors under different dietary conditions: + sucrose, Molecular analyses revealed that expression levels capa, dh44, were significantly altered sugar-fed flies compared group only sucrose. Through trials testing synergistic peptide injection sugar consumption, DH44 consistently increased mortality all diet groups. These findings offer molecular insights development novel pest management strategies targeting suzukii.

Язык: Английский

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Re‐evaluation of erythritol (E 968) as a food additive

EFSA Journal, Год журнала: 2023, Номер 21(12)

Опубликована: Дек. 1, 2023

Abstract This opinion addresses the re-evaluation of erythritol (E 968) as food additive and an application for its exemption from laxative warning label requirement established under Regulation (EU) No 1169/2011. Erythritol is a polyol obtained by fermentation with Moniliella pollinis BC or megachiliensis KW3-6, followed purifications drying. readily dose-dependently absorbed in humans can be metabolised to erythronate small extent. then excreted unchanged urine. It does not raise concerns regarding genotoxicity. The dataset evaluated consisted human interventional studies. Panel considered that has potential cause diarrhoea humans, which was adverse because association electrolyte water imbalance. lower bound range no observed effect levels (NOAELs) 0.5 g/kg body weight (bw) identified reference point. appropriate set numerical acceptable daily intake (ADI) at level An ADI bw per day protective immediate well chronic effects, secondary diarrhoea. highest mean 95th percentile exposure children (742 mg/kg day) adolescents (1532 day). Acute maximally 3531 meal 99th percentile. Overall, both dietary assessments overestimation. concluded estimates acute were above ADI, indicating individuals high may risk experiencing effects after single repeated exposure. Concerning new application, available data do support proposal exemption.

Язык: Английский

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Insecticidal Properties of Erythritol on Four Tropical Tephritid Fruit Flies, Zeugodacus cucurbitae, Ceratitis capitata, Bactrocera dorsalis, and B. latifrons (Diptera: Tephritidae)

Insects, Год журнала: 2023, Номер 14(5), С. 472 - 472

Опубликована: Май 16, 2023

Tephritid fruit flies are among the most destructive agricultural pests of fruits and vegetables worldwide can impose trade barriers against movement fresh tropical commodities. Primary pre-harvest control methods for these rely on spraying conventional chemical insecticides or bait sprays. However, resistance to has been reported in flies. Erythritol is a non-nutritive sugar alternative human consumption, which tested confirmed its insecticidal properties various insect pest species. In this study, using laboratory bioassays, we evaluated effect erythritol alone formulations containing sucrose and/or protein four fly species established Hawaii (e.g., melon fly, Mediterranean oriental Malaysian fly). addition, effects other hexose pentose alcohols, such as sorbitol, mannitol, xylitol, were tested. Among different standalone combinatory treatments tested, 1M formulation 2M + 0.5M appeared be detrimental survival all flies, suggesting potential non-toxic management tool tephritid

Язык: Английский

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Erythritol sprays reduce Drosophila suzukii infestation without impacting honey bee visitation nor fruit quality

Pest Management Science, Год журнала: 2023, Номер 79(12), С. 4990 - 5002

Опубликована: Авг. 4, 2023

Abstract BACKGROUND Spotted‐wing drosophila, Drosophila suzukii , is an economic pest of small fruits and cherries. Insecticides primarily control this while alternative controls are in development. Laboratory studies show that erythritol insecticidal to D. other pests approved for human consumption. Moreover, combined with sucrose or non‐caloric sucralose can stimulate feeding quicken mortality. Before growers use erythritol, the impact on crop protection, non‐target insects, fruit quality need evaluation. RESULTS In three blueberry cherry field cage trials, oviposition sprayed erythritol:sucrose erythritol:sucralose formulations was lowered by 59%–81% compared unsprayed controls. Fly infestation (larval adult counts from fruit) 90% lower a greenhouse trial, 49% open trial 2 m : 0.5 sucrose. Infestation also 57% 1.5 erythritol:0.5 Other trials very low pressure frequent rains revealed no differences Field consistently honey bees did not preferentially visit plants either formulation, although yellow jackets visited more frequently. Erythritol led leaf spotting, but there reduction treated blueberries cherries terms mold development, firmness, diameter, epidermal penetration force, Brix° (total soluble solids) at harvest. CONCLUSION Eleven conducted over four years reduce without attracting foraging nor negatively impacting quality. © 2023 Society Chemical Industry. This article has been contributed U.S. Government employees their work public domain USA.

Язык: Английский

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The impact of sugar diet on humidity preference, survival, and host landing in mosquitoes

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Сен. 25, 2024

Mosquito-borne diseases have caused more than one million deaths each year. There is an urgent need to develop effective way reduce mosquito-host interaction mitigate disease transmission. Sugar diets long been linked abnormal physiology in animals, making them potential candidates for mosquito control. Here, we show the impact of sugar on humidity preference and survival

Язык: Английский

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