Enzymatic Bioremediation of Organophosphate Compounds—Progress and Remaining Challenges DOI Creative Commons
Meghna Thakur, Igor L. Medintz, Scott A. Walper

и другие.

Frontiers in Bioengineering and Biotechnology, Год журнала: 2019, Номер 7

Опубликована: Ноя. 8, 2019

Organophosphate compounds are ubiquitously employed as agricultural pesticides and maintained chemical warfare agents by several nations. These highly toxic, show environmental persistence accumulation, contribute to numerous cases of poisoning death each year. While their use weapons mass destruction is rare, these never fully disappear into obscurity they continue be tools fear control governments terrorist organizations. Beyond weaponization, wide-scale dissemination products has led accumulation intoxication soil water across the globe. Therefore, there a dire need for rapid safe bioremediation, personal decontamination, therapeutic detoxicants. hydrolyzing enzymes emerging appealing targets satisfy decontamination needs owing ability hydrolyze both nerve using biologically-derived materials environment individual. As release genetically modified organisms not widely accepted practice, researchers exploring alternative strategies organophosphate bioremediation that focus on cell-free enzyme systems. In this review, we first discuss more prevalent organophosphorus along with research engineering efforts have an enhancement in activity, substrate tolerance, stability. later half advances achieved through focusing enhancing catalytic activity stability phosphotriesterase, model hydrolase, various approaches such nanoparticle display, DNA scaffolding, outer membrane vesicle encapsulation.

Язык: Английский

Biotechnological basis of microbial consortia for the removal of pesticides from the environment DOI

Pankaj Bhatt,

Kalpana Bhatt,

Anita Sharma

и другие.

Critical Reviews in Biotechnology, Год журнала: 2021, Номер 41(3), С. 317 - 338

Опубликована: Март 17, 2021

The application of microbial strains as axenic cultures has frequently been employed in a diverse range sectors. In the natural environment, microbes exist multispecies and perform better than monocultures. Cell signaling communication pathways play key role engineering consortia, because consortium, microorganisms communicate via diffusible signal molecules. Mixed have gained little attention due to lack proper knowledge about their interactions with each other. Some ideas proposed deal study various when they live together community, for biotechnological purposes. environments, can possess unique metabolic features. Therefore, consortia divide burden among group robustly pesticide degradation. Synthetic desired functions at naturally contaminated sites. this article, special is paid function environment. This review comprehensively discusses recent applications degradation environmental bioremediation. Moreover, future directions synthetic explored. also explores perspectives new platforms these approaches, besides highlighting practical understanding scientific information behind consortia.

Язык: Английский

Процитировано

163

Pesticides impacts on human health and the environment with their mechanisms of action and possible countermeasures DOI Creative Commons
Md Faruque Ahmad,

Fakhruddin Ali Ahmad,

Abdulrahman A. Alsayegh

и другие.

Heliyon, Год журнала: 2024, Номер 10(7), С. e29128 - e29128

Опубликована: Апрель 1, 2024

Pesticides are chemical constituents used to prevent or control pests, including insects, rodents, fungi, weeds, and other unwanted organisms. Despite their advantages in crop production disease management, the use of pesticides poses significant hazards environment public health. Pesticide elements have now perpetually entered our atmosphere subsequently contaminated water, food, soil, leading health threats ranging from acute chronic toxicities. can cause toxicity if a high dose is inhaled, ingested, comes into contact with skin eyes, while prolonged recurrent exposure leads toxicity. produce different types toxicity, for instance, neurotoxicity, mutagenicity, carcinogenicity, teratogenicity, endocrine disruption. The pesticide formulation may depend on specific active ingredient presence synergistic inert compounds that enhance modify its Safety concerns need hour contemporary pesticide-induced hazards. effectiveness implementation current legislature providing ample protection human key concerns. This review explored comprehensive summary regarding updated impacts advanced safety legislation. Implementing regulations, proper training, education help mitigate negative promote safer more sustainable agricultural practices.

Язык: Английский

Процитировано

155

Endophytic Nanotechnology: An Approach to Study Scope and Potential Applications DOI Creative Commons
Mukesh Meena,

Andleeb Zehra,

Prashant Swapnil

и другие.

Frontiers in Chemistry, Год журнала: 2021, Номер 9

Опубликована: Май 25, 2021

Nanotechnology has become a very advanced and popular form of technology with huge potentials. been well explored in the fields electronics, automobiles, construction, medicine, cosmetics, but exploration nanotecnology’s use agriculture is still limited. Due to climate change, each year around 40% crops face abiotic biotic stress; global demand for food increasing, nanotechnology seen as best method mitigate challenges disease management by reducing chemical inputs such herbicides, pesticides, fungicides. The these toxic chemicals potentially harmful humans environment. Therefore, using NPs fungicides/ bactericides or nanofertilizers, due their small size high surface area reactivity, reduces problems plant management. There are several methods that have used synthesize NPs, physical methods. Specially, we need ecofriendly nontoxic synthesis NPs. Some biological organisms like plants, algae, yeast, bacteria, actinomycetes, fungi emerged superlative candidates (also considered green synthesis). Among methods, endophytic microorganisms widely low metallic ions, which opens new possibility on edge nanotechnology. In this review, will discussed different top-down, bottom-up, (specially including microorganisms) mechanisms, forms magnesium oxide nanoparticles (MgO-NPs), copper (Cu-NPs), chitosan (CS-NPs), β-d-glucan (GNPs), engineered (quantum dots, metalloids, nonmetals, carbon nanomaterials, dendrimers, liposomes), molecular approaches various aspects. At level, nanoparticles, mesoporous silica (MSN) RNA-interference molecules, can also be tools carry genetic material during engineering plants. management, biosensors diagnose disease.

Язык: Английский

Процитировано

147

Nano-Enabled Products: Challenges and Opportunities for Sustainable Agriculture DOI Creative Commons
Vishnu D. Rajput, Abhishek Singh, Tatiana Minkina

и другие.

Plants, Год журнала: 2021, Номер 10(12), С. 2727 - 2727

Опубликована: Дек. 11, 2021

Nanotechnology has gained popularity in recent years owing to its established potential for application and implementation various sectors such as medical drugs, medicine, catalysis, energy, material, plant science. Nanoparticles (NPs) are smaller size (1–100 nm) with a larger surface area have many fruitful applications. The extraordinary functions of NPs utilized sustainable agriculture due nano-enabled products, e.g., nano-insecticides, nano-pesticides, nano-fertilizers. lately been suggested an alternate method controlling pests insects, fungi, weeds. Several exhibit antimicrobial properties considered food packaging processes; example, Ag-NPs commonly used purposes. Apart from their properties, Si, Ag, Fe, Cu, Al, Zn, ZnO, TiO2, CeO2, Al2O3, carbon nanotubes also demonstrated negative impacts on growth development. This review examines the field-use products agriculture, future perspectives, growing environmental concerns. remarkable information commercialized allied provided.

Язык: Английский

Процитировано

146

Redox toxicology of environmental chemicals causing oxidative stress DOI Creative Commons
Fuli Zheng, Filipe Marques Gonçalves, Yumi Abiko

и другие.

Redox Biology, Год журнала: 2020, Номер 34, С. 101475 - 101475

Опубликована: Апрель 18, 2020

Living organisms are surrounded with heavy metals such as methylmercury, manganese, cobalt, cadmium, arsenic, well pesticides deltamethrin and paraquat, or atmospheric pollutants quinone. Extensive studies have demonstrated a strong link between environmental human health. Redox toxicity is proposed one of the main mechanisms chemical-induced pathology in humans. Acting both sensor oxidative stress positive regulator antioxidants, nuclear factor erythroid 2-related 2 (NRF2) has attracted recent attention. However, role NRF2 plays pollutant-induced not been systematically addressed. Here, we characterize function response to various pollutants, metals, quinones. related signaling pathways epigenetic regulations also reviewed.

Язык: Английский

Процитировано

144

Microbial degradation of recalcitrant pesticides: a review DOI
Sanchali Bose, P. Senthil Kumar, Dai‐Viet N. Vo

и другие.

Environmental Chemistry Letters, Год журнала: 2021, Номер 19(4), С. 3209 - 3228

Опубликована: Апрель 15, 2021

Язык: Английский

Процитировано

139

Insights into insecticide-resistance mechanisms in invasive species: Challenges and control strategies DOI Creative Commons
Junaid Ali Siddiqui, Ruidong Fan, Hira Naz

и другие.

Frontiers in Physiology, Год журнала: 2023, Номер 13

Опубликована: Янв. 9, 2023

Threatening the global community is a wide variety of potential threats, most notably invasive pest species. Invasive species are non-native organisms that humans have either accidentally or intentionally spread to new regions. One effective and first lines control strategies for controlling pests application insecticides. These toxic chemicals employed get rid pests, but they pose great risks people, animals, plants. Pesticides heavily used in managing current era. Due overuse synthetic chemicals, numerous already developed resistance. The resistance development main reason failure manage Developing pesticide management techniques necessitates thorough understanding mechanisms through which insects acquire insecticide Insects use behavioral, biochemical, physiological, genetic, metabolic methods deal with can lead continuous overexpression detoxifying enzymes. An overabundance enzymes causes resistance, pesticides rendering them ineffective against pests. A key factor amplification certain enzymes, specifically esterases, Glutathione S-transferase, Cytochromes p450 monooxygenase, hydrolyses. Additionally, insect guts offer unique habitats microbial colonization, gut bacteria may serve their hosts useful services. Most importantly, detoxification insecticides leads development. complete knowledge could be very helpful coping challenges effectively developing Integrated Pest Management particularly at lowering risk chemical environmental contaminants resulting health issues, it also ways

Язык: Английский

Процитировано

126

The Versatility in the Applications of Dithiocarbamates DOI Open Access
Timothy O. Ajiboye, Titilope Tinu Ajiboye, Riadh Marzouki

и другие.

International Journal of Molecular Sciences, Год журнала: 2022, Номер 23(3), С. 1317 - 1317

Опубликована: Янв. 24, 2022

Dithiocarbamate ligands have the ability to form stable complexes with transition metals, and this chelating has been utilized in numerous applications. The also used synthesize other useful compounds. Here, up-to-date applications of dithiocarbamate are extensively discussed. Some these their use as enzyme inhibitor treatment HIV diseases. application anticancer, antimicrobial, medical imaging anti-inflammatory agents is examined. Moreover, industry vulcanization accelerator, froth flotation collector, antifouling, coatings, lubricant additives sensors various ways which they employed synthesis compounds highlighted. Finally, agricultural uses remediation heavy metals via comprehensively

Язык: Английский

Процитировано

103

Organophosphate pesticide residues in environmental and biological matrices: Occurrence, distribution and potential remedial approaches DOI Creative Commons
Odunayo T. Ore, Adedapo O. Adeola, Ajibola A. Bayode

и другие.

Environmental Chemistry and Ecotoxicology, Год журнала: 2022, Номер 5, С. 9 - 23

Опубликована: Окт. 25, 2022

The prevalent occurrence of organophosphate pesticides in the environment is widely accompanied by severe adverse impacts on environmental matrices and humans owing to their bioaccumulation food chain or direct exposure. Despite intervention regulatory agencies levels pesticide residues, studies have shown that these congeners are still present human blood serum urine as well soil, sediments, water, air. This, therefore, requires adoption both conventional newly developed methods for total mitigation matrices. ubiquitous nature this group xenobiotics biological matrices, particularly at alarming concentrations reported reviewed studies, responsible its attendant health ecological impacts. Based available evidence, predominant source agricultural application. Although class persistent organic pollutants relatively less than organochlorine counterparts, nevertheless, neurotoxic effects cannot be undermined. Adequate measures must taken regulate storage usage farmlands. It also recommended more eco-friendly sustainable approaches should circumvent distressing pesticides. In review article, special attention given residues This article comprehensively discusses recent advances remediation whilst exploring future perspectives remedial approaches.

Язык: Английский

Процитировано

85

Beyond Human Nutrition of Edible Insects: Health Benefits and Safety Aspects DOI Creative Commons
José E. Aguilar-Toalá, Rosy G. Cruz-Monterrosa, Andrea M. Liceaga

и другие.

Insects, Год журнала: 2022, Номер 13(11), С. 1007 - 1007

Опубликована: Ноя. 1, 2022

Nowadays, edible insects are considered an outstanding source of nutrients, primarily because they contain high-quality protein, amino acids, and vitamins. Insects a promising alternative protein towards alleviating future global food shortage problems due to their production as being more sustainable by using less agricultural land water, well releasing smaller amount greenhouse gas emissions. However, other important aspects consider about the consumption include health benefits some safety aspects, which has been relatively overlooked. In this sense, bioactive compounds that can provide diverse bioactivities, such antioxidant, antihypertensive, anti-inflammatory, antimicrobial, immunomodulatory with positive impact on human health. On hand, nutrient-rich perfect growth medium for microorganisms, possess anti-nutritive factors. These two main could represent concerns consumers. context, recent scientific evidence indicates preservation methods, mainly thermal treatments, utilized in cooking or processing decreased microbial levels factors, suggests do not critical biological risk humans. Besides, have effect gut microbiota, either pre-biotic antimicrobial activity pathogens. Thus, review is focused studies related isolated components, discussion potential issues content factors; will synopsis whether may be safe consumption.

Язык: Английский

Процитировано

82