Antioxidants,
Год журнала:
2023,
Номер
12(4), С. 860 - 860
Опубликована: Апрель 2, 2023
It
is
more
effective
to
maintain
good
health
than
regain
it
after
losing
it.
This
work
focuses
on
the
biochemical
defense
mechanisms
against
free
radicals
and
their
role
in
building
maintaining
antioxidant
shields,
aiming
show
how
balance,
as
much
possible,
situations
which
we
are
exposed
radicals.
To
achieve
this
aim,
foods,
fruits,
marine
algae
with
a
high
content
should
constitute
basis
of
nutritional
elements,
since
natural
products
known
have
significantly
greater
assimilation
efficiency.
review
also
gives
perspective
use
antioxidants
can
extend
life
food
products,
by
protecting
them
from
damage
caused
oxidation
well
additives.
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(3), С. 1989 - 1989
Опубликована: Янв. 19, 2023
The
endocannabinoid
system
(ECS)
is
involved
in
various
processes,
including
brain
plasticity,
learning
and
memory,
neuronal
development,
nociception,
inflammation,
appetite
regulation,
digestion,
metabolism,
energy
balance,
motility,
regulation
of
stress
emotions.
Physical
exercise
(PE)
considered
a
valuable
non-pharmacological
therapy
that
an
immediately
available
cost-effective
method
with
lot
health
benefits,
one
them
being
the
activation
endogenous
cannabinoids.
Endocannabinoids
(eCBs)
are
generated
as
response
to
high-intensity
activities
can
act
short-term
circuit
breakers,
generating
antinociceptive
responses
for
short
variable
period
time.
A
runner's
high
ephemeral
feeling
some
sport
practitioners
experience
during
endurance
activities,
such
running.
release
eCBs
sustained
physical
appears
be
triggering
this
phenomenon.
last
decades
have
been
characterized
by
increased
interest
emotional
state
induced
exercise,
it
believed
alleviate
pain,
induce
mild
sedation,
increase
euphoric
levels,
anxiolytic
effects.
This
review
provides
information
about
current
knowledge
endocannabinoids
effort
also
overview
studies
published
specialized
literature
subject.
Nutrients,
Год журнала:
2023,
Номер
15(10), С. 2371 - 2371
Опубликована: Май 18, 2023
The
role
of
reactive
oxygen
species
and
antioxidant
response
in
training
adaptations
sports
performance
has
been
a
large
issue
investigated
the
last
few
years.
present
review
aims
to
analyze
performance.
For
this
aim,
production
physical
activities,
effect
on
performance,
relationship
between
adaptations,
inflammation,
microbiota,
antioxidants
recovery
strategies
use
supplementations
will
be
discussed.
Finally,
practical
applications
derived
from
information
are
(ROS)
during
activity
greatly
influences
This
concludes
that
ROS
play
critical
processes
adaptation
induced
by
resistance
through
reduction
inflammatory
mediators
oxidative
stress,
as
well
appropriate
molecular
signaling.
Additionally,
it
established
micronutrients
an
important
counteracting
free
radicals,
such
species,
which
cause
effects
recovery,
for
using
supplements,
vitamin
C,
E,
resveratrol,
coenzyme
Q10,
selenium,
curcumin
enhance
mental
well-being.
Male
reproductive
function
is
highly
susceptible
to
oxidative
stress,
which
arises
from
an
imbalance
between
reactive
oxygen
species
(ROS)
production
and
antioxidant
defense
mechanisms.
Oxidative
stress
can
significantly
impair
sperm
quality,
including
count,
motility,
morphology,
DNA
integrity,
leading
male
infertility.
Antioxidants
play
a
crucial
role
in
maintaining
health
by
neutralizing
ROS
protecting
cells
damage.
This
review
article
explores
the
impact
of
on
investigates
potential
benefits
supplementation
mitigating
its
detrimental
effects.
A
comprehensive
literature
search
was
conducted
gather
relevant
studies
examining
effects
fertility
outcomes
supplementation.
The
findings
reveal
that
improve
some
individuals.
However,
conflicting
research
limitations
study
design
highlight
need
for
further
investigation.
Factors
such
as
individual
variations,
underlying
causes
infertility,
dosage,
duration
should
be
carefully
considered.
Lifestyle
modifications,
healthy
diet
exercise,
are
reducing
optimizing
health.
provides
valuable
insights
into
complex
relationship
function,
emphasizing
supportive
strategy.
Further
warranted
establish
optimal
protocols,
identify
specific
subgroups
may
benefit
most,
explore
advancements
therapies
outcomes.
Frontiers in Physiology,
Год журнала:
2024,
Номер
15
Опубликована: Фев. 19, 2024
Obesity
has
become
one
of
the
global
epidemics,
contributing
to
burden
disease
in
society,
increasing
risk
diabetes,
cardiovascular
and
liver
diseases.
Inadequate
energy
balance
resulting
from
excessive
intake
insufficient
physical
activity
(PA)
is
main
factors
incidence
obesity
development
metabolic
syndrome
(MetS).
Treatment
options
for
include
lifestyle
modifications,
pharmacotherapy
bariatric
surgery,
with
latter
being
most
effective
treatment.
Lifestyle
interventions
involving
increased
PA
reduced
caloric
improve
outcomes.
Early
implementation
exercise
leads
improved
fitness,
better
glycemic
control
lipid
profile.
Undertaking
systematic
associated
quality
life,
improves
insulin
sensitivity,
causes
additional
weight
loss,
reduces
its
adverse
effects
on
bone
mass
results
body
composition.
In
this
narrative
review
we
summarized
current
state
knowledge
impact
components
MetS
latest
recommendations
patients
MetS.
Biomolecules,
Год журнала:
2025,
Номер
15(1), С. 151 - 151
Опубликована: Янв. 20, 2025
Quercetin,
a
flavonoid
found
in
vegetables
and
fruits,
has
been
extensively
studied
for
its
health
benefits
disease
management.
Its
role
the
prevention
of
various
pathogenesis
well-documented,
primarily
through
ability
to
inhibit
oxidative
stress,
inflammation,
enhance
endogenous
antioxidant
defense
mechanisms.
Electronic
databases
such
as
Google
Scholar,
Scopus,
PubMed,
Medline,
Web
Science
were
searched
information
regarding
quercetin
pathogeneses.
The
included
literature
comprised
experimental
studies,
randomized
controlled
trials,
epidemiological
studies
related
quercetin,
while
editorials,
case
analyses,
theses,
letters
excluded.
It
reported
have
wide
range
including
hepatoprotective,
antidiabetic,
anti-obesity,
neuroprotective,
cardioprotective,
wound
healing,
antimicrobial,
immunomodulatory
effects,
achieved
modulation
biological
activities.
Additionally,
numerous
vitro
vivo
shown
that
quercetin’s
efficacies
cancer
management
involve
inhibiting
cell
signaling
pathways,
cycle,
angiogenesis,
activating
pathways
tumor
suppressor
genes,
inducing
apoptosis.
This
review
aims
provide
comprehensive
understanding
this
outlines
sources
nanoformulations,
applications
management,
along
with
key
findings
from
important
clinical
trial
studies.
Limited
data
safety
mechanism
action
are
available.
is
conduct
more
trials
gain
deeper
disease-preventive
potential,
mechanisms
action,
safety,
optimal
therapeutic
dosages.
Furthermore,
research
based
on
nanoformulations
should
be
performed
minimize/overcome
hindrance
associated
bioavailability,
rapid
degradation,
toxicity.
Prescribing
physical
exercise
as
part
of
the
clinical
treatment
cancer
patients
has
become
an
important
strategy
in
therapeutic
arsenal
available
main
health
centers
specialized
neoplastic
diseases,
but
there
is
still
uncertainty
regarding
role
regular
activity
modifying
oxidative
stress
markers
and
antioxidants,
high
levels
can
lead
to
development
carcinogens.
Therefore,
we
assessed
effect
versus
absence
on
antioxidants
patients.
We
looked
for
randomized
controlled
trials
that
included
adult
with
any
type
performing
some
compared
them
a
control
group
no
activity.
The
outcomes
interest
collected
were
antioxidants.
Six
databases
used
search
(EMBASE,
Cochrane
Library
(CENTRAL),
US
National
Medicine
(PubMed),
Physiotherapy
Evidence
Database
(PEDro),
Cumulative
Index
Nursing
Allied
Health
(CINAHL)
SPORTDiscus
via
EBSCO)
until
January
31st,
2024.
In
end,
7
included,
totaling
573
participants.
It
was
possible
conduct
meta-analysis
demonstrated
potentially
increases
antioxidant
marker
Trolox,
Taoc,
Gpx,
(SMD
=
1.23,
CI:
0.13
2.34).
However,
these
findings
classified
having
very
low
moderate
GRADE
evidence.
Cancer
who
participated
programs
may
have
exhibited
increased
concentration
Although
overall
quality
evidence
studies
low,
represent
field
research
should
be
guided
by
more
participants
homogeneous
methods
analysis
oxidant
markers.
PROSPERO
CRD42021257815.
